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3L7F

Structure of IL-13 antibody H2L6, A humanized variant OF C836

Summary for 3L7F
Entry DOI10.2210/pdb3l7f/pdb
Related3L5W 3L5X 3L5Y 3L7E
DescriptorH2L6 LIGHT CHAIN, H2L6 HEAVY CHAIN, SULFATE ION, ... (5 entities in total)
Functional Keywordsimmunoglobulin fold, monoclonal antibody, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains6
Total formula weight143120.60
Authors
Teplyakov, A.,Obmolova, G.,Malia, T.,Gilliland, G.L. (deposition date: 2009-12-28, release date: 2010-11-10, Last modification date: 2023-09-06)
Primary citationFransson, J.,Teplyakov, A.,Raghunathan, G.,Chi, E.,Cordier, W.,Dinh, T.,Feng, Y.,Giles-Komar, J.,Gilliland, G.,Lollo, B.,Malia, T.J.,Nishioka, W.,Obmolova, G.,Zhao, S.,Zhao, Y.,Swanson, R.V.,Almagro, J.C.
Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398:214-231, 2010
Cited by
PubMed: 20226193
DOI: 10.1016/j.jmb.2010.03.004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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