5E2W

Anti-TAU AT8 FAB with triply phosphorylated TAU peptide

Summary for 5E2W

• Entry DOI: 10.2210/pdb5e2w/pdb
• Related: 5E2T 5E2U 5E2V
• Descriptor: AT8 LIGHT CHAIN, AT8 HEAVY CHAIN, TAU-PHOSPHOPEPTIDE, ... (4 entities in total)
• Functional Keywords: immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 50167.49

Authors

Malia, T.,Teplyakov, A. (deposition date: 2015-10-01, release date: 2016-02-24, Last modification date: 2023-09-27)

• Primary citation: Malia, T.J.,Teplyakov, A.,Ernst, R.,Wu, S.J.,Lacy, E.R.,Liu, X.,Vandermeeren, M.,Mercken, M.,Luo, J.,Sweet, R.W.,Gilliland, G.L.; Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.; Proteins, 84:427-434, 2016; PubMed: 26800003; DOI: 10.1002/prot.24988

Experimental method

X-RAY DIFFRACTION (1.5 Å)