Author results

2WZQ
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INSERTION MUTANT E173GP174 OF THE NS3 PROTEASE-HELICASE FROM DENGUE VIRUS
Descriptor:NS3 PROTEASE-HELICASE, CHLORIDE ION, GLYCEROL
Authors:Luo, D., Wei, N., Doan, D., Paradkar, P., Chong, Y., Davidson, A., Kotaka, M., Lescar, J., Vasudevan, S.
Deposit date:2009-12-02
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Flexibility between the Protease and Helicase Domains of the Dengue Virus Ns3 Protein Conferred by the Linker Region and its Functional Implications.
J.Biol.Chem., 285, 2010
2WHX
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A SECOND CONFORMATION OF THE NS3 PROTEASE-HELICASE FROM DENGUE VIRUS
Descriptor:SERINE PROTEASE/NTPASE/HELICASE NS3, SERINE PROTEASE SUBUNIT NS2B, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Luo, D., Lescar, J.
Deposit date:2009-05-07
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Flexibility between the Protease and Helicase Domains of the Dengue Virus Ns3 Protein Conferred by the Linker Region and its Functional Implications.
J.Biol.Chem., 285, 2010
2YKG
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STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I
Descriptor:PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', ZINC ION, ...
Authors:Luo, D., Pyle, A.M.
Deposit date:2011-05-27
Release date:2011-10-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into RNA Recognition by Rig-I.
Cell(Cambridge,Mass.), 147, 2011
4AY2
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CAPTURING 5' TRI-PHOSPHORYLATED RNA DUPLEX BY RIG-I
Descriptor:PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, 5'-R-PPP(GP*GP*CP*GP*CP*GP*GP*CP*UP*UP*CP*GP*GP*CP *CP*GP*CP*GP*CP*C)-3', ZINC ION, ...
Authors:Luo, D., Pyle, A.M.
Deposit date:2012-06-17
Release date:2012-10-03
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I.
Structure, 20, 2012
4BPB
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STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I
Descriptor:PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', ZINC ION, ...
Authors:Luo, D., Pyle, A.M.
Deposit date:2013-05-23
Release date:2013-06-19
Method:X-RAY DIFFRACTION (2.584 Å)
Cite:Structural Insights Into RNA Recognition by Rig-I.
Cell(Cambridge,Mass.), 147, 2011
3ZD6
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SNAPSHOT 1 OF RIG-I SCANNING ON RNA DUPLEX
Descriptor:PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, RNA DUPLEX, ZINC ION
Authors:Luo, D., Pyle, A.M.
Deposit date:2012-11-25
Release date:2013-08-07
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Defining the Functional Determinants for RNA Surveillance by Rig-I.
Embo Rep., 14, 2013
3ZD7
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SNAPSHOT 3 OF RIG-I SCANNING ON RNA DUPLEX
Descriptor:PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, RNA DUPLEX, ZINC ION, ...
Authors:Luo, D., Pyle, A.M.
Deposit date:2012-11-25
Release date:2013-08-07
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Defining the Functional Determinants for RNA Surveillance by Rig-I.
Embo Rep., 14, 2013
1SCZ
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IMPROVED STRUCTURAL MODEL FOR THE CATALYTIC DOMAIN OF E.COLI DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE
Descriptor:Dihydrolipoamide Succinyltransferase
Authors:Schormann, N., Symersky, J., Carson, M., Luo, M., Tsao, J., Johnson, D., Huang, W.-Y., Pruett, P., Lin, G., Li, S., Qiu, S., Arabashi, A., Bunzel, B., Luo, D., Nagy, L., Gray, R., Luan, C.-H., Zhang, Z., Lu, S., DeLucas, L.
Deposit date:2004-02-12
Release date:2004-03-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase
To be Published
1SPX
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CRYSTAL STRUCTURE OF GLUCOSE DEHYDROGENASE OF CAENORHABDITIS ELEGANS IN THE APO-FORM
Descriptor:short-chain reductase family member (5L265)
Authors:Schormann, N., Zhou, J., McCombs, D., Bray, T., Symersky, J., Huang, W.-Y., Luan, C.-H., Gray, R., Luo, D., Arabashi, A., Bunzel, B., Nagy, L., Lu, S., Li, S., Lin, G., Zhang, Y., Qiu, S., Tsao, J., Luo, M., Carson, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-03-17
Release date:2004-03-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Glucose Dehydrogenase of Caenorhabditis Elegans in the Apo-Form: A Member of the SDR-Family
To be Published
1XHL
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CRYSTAL STRUCTURE OF PUTATIVE TROPINONE REDUCTASE-II FROM CAENORHABDITIS ELEGANS WITH COFACTOR AND SUBSTRATE
Descriptor:Short-chain dehydrogenase/reductase family member (5L265), putative Tropinone Reductase-II, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schormann, N., Karpova, E., Zhou, J., Zhang, Y., Symersky, J., Bunzel, R., Huang, W.-Y., Arabshahi, A., Qiu, S., Luan, C.-H., Gray, R., Carson, M., Tsao, J., Luo, M., Johnson, D., Lu, S., Lin, G., Luo, D., Cao, Z., Li, S., McKInstry, A., Shang, Q., Chen, Y.-J., Bray, T., Nagy, L., DeLucas, L., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-20
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate
To be Published
1XKQ
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CRYSTAL STRUCTURE OF SHORT-CHAIN DEHYDROGENASE/REDUCTASE OF UNKNOWN FUNCTION FROM CAENORHABDITIS ELEGANS WITH COFACTOR
Descriptor:short-chain reductase family member (5D234), NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Schormann, N., Zhou, J., Karpova, E., Zhang, Y., Symersky, J., Bunzel, B., Huang, W.-Y., Arabshahi, A., Qiu, S., Luan, C.-H., Gray, R., Carson, M., Tsao, J., Luo, M., Johnson, D., Lu, S., Lin, G., Luo, D., Cao, Z., Li, S., McKinstry, A., Shang, Q., Chen, Y.-J., Bray, T., Nagy, L., DeLucas, L., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-29
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Short-Chain Dehydrogenase/Reductase of unknown Function from Caenorhabditis Elegans with Cofactor
To be Published
1YIS
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: ADENYLOSUCCINATE LYASE
Descriptor:adenylosuccinate lyase, SULFATE ION
Authors:Symersky, J., Schormann, N., Lu, S., Zhang, Y., Karpova, E., Qiu, S., Huang, W., Cao, Z., Zhou, J., Luo, M., Arabshahi, A., McKinstry, A., Luan, C.-H., Luo, D., Johnson, D., An, J., Tsao, J., Delucas, L., Shang, Q., Gray, R., Li, S., Bray, T., Chen, Y.-J., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-01-12
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase
To be Published
2B34
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STRUCTURE OF MAR1 RIBONUCLEASE FROM CAENORHABDITIS ELEGANS
Descriptor:MAR1 Ribonuclease
Authors:Schormann, N., Karpova, E., Li, S., Symersky, J., Zhang, Y., Lu, S., Zhou, Q., Lin, G., Cao, Z., Luo, M., Qiu, S., Luan, C.-H., Luo, D., Huang, W., Shang, Q., McKinstry, A., An, J., Tsao, J., Carson, M., Stinnett, M., Chen, Y., Johnson, D., Gary, R., Arabshahi, A., Bunzel, R., Bray, T., DeLucas, L., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-09-19
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structure of MAR1 Ribonuclease from Caenorhabditis elegans
To be Published
1PZV
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CRYSTAL STRUCTURES OF TWO UBC (E2) ENZYMES OF THE UBIQUITIN-CONJUGATING SYSTEM IN CAENORHABDITIS ELEGANS
Descriptor:Probable ubiquitin-conjugating enzyme E2-19 kDa
Authors:Schormann, N., Lin, G., Li, S., Symersky, J., Qiu, S., Finley, J., Luo, D., Stanton, A., Carson, M., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-07-14
Release date:2003-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans
To be Published
1OOE
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS : DIHYDROPTERIDINE REDUCTASE
Descriptor:Dihydropteridine reductase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Symersky, J., Li, S., Nagy, L., Qiu, S., Lin, G., Tsao, J., Luo, D., Carson, M., DeLucas, L., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-03-03
Release date:2003-03-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural genomics of Caenorhabditis elegans: structure of dihydropteridine reductase.
Proteins, 53, 2003
1Q34
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CRYSTAL STRUCTURES OF TWO UBC (E2) ENZYMES OF THE UBIQUITIN-CONJUGATING SYSTEM IN CAENORHABDITIS ELEGANS
Descriptor:Ubiquitin-conjugating enzyme E2-21.5 kDa
Authors:Schormann, N., Lin, G., Li, S., Symersky, J., Qiu, S., Finley, J., Luo, D., Stanton, A., Carson, M., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-07-28
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of two UBC (E2) enzymes of the ubiquitin-conjugating system in Caenorhabditis elegans
To be Published
1T9F
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: STRUCTURE OF A PROTEIN WITH UNKNOWN FUNCTION
Descriptor:protein 1d10, MALONATE ION
Authors:Symersky, J., Li, S., Bunzel, R., Schormann, N., Luo, D., Huang, W.Y., Qiu, S., Gray, R., Zhang, Y., Arabashi, A., Lu, S., Luan, C.H., Tsao, J., DeLucas, L., Luo, M., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-05-16
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function.
To be Published
1PGV
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STRUCTURAL GENOMICS OF CAENORHABDITIS ELEGANS: TROPOMODULIN C-TERMINAL DOMAIN
Descriptor:tropomodulin TMD-1
Authors:Symersky, J., Lu, S., Li, S., Chen, L., Meehan, E., Luo, M., Qiu, S., Bunzel, R.J., Luo, D., Arabashi, A., Nagy, L.A., Lin, G., Luan, W.C.-H., Carson, M., Gray, R., Huang, W., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-05-28
Release date:2003-06-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural genomics of Caenorhabditis elegans: crystal structure of the tropomodulin C-terminal domain
Proteins, 56, 2004
4DN8
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STRUCTURE OF PORCINE SURFACTANT PROTEIN D NECK AND CARBOHYDRATE RECOGNITION DOMAIN COMPLEXED WITH MANNOSE
Descriptor:Pulmonary surfactant-associated protein D, CALCIUM ION, BETA-D-MANNOSE
Authors:van Eijk, M., Rynkiewicz, M.J., White, M.R., Hartshorn, K.L., Zou, X., Schulten, K., Luo, D., Crouch, E.C., Cafarella, T.M., Head, J.F., Haagsman, H.P., Seaton, B.A.
Deposit date:2012-02-08
Release date:2012-06-20
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Unique Sugar-binding Site Mediates the Distinct Anti-influenza Activity of Pig Surfactant Protein D.
J.Biol.Chem., 287, 2012
5XC6
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DENGUE VIRUS 4 NS3 HELICASE IN COMPLEX WITH SSRNA SLA12
Descriptor:NS3 Helicase, RNA (5'-R(*AP*GP*UP*UP*GP*UP*UP*AP*GP*UP*CP*U)-3'), PHOSPHATE ION
Authors:Swarbrick, C.M.D., Basavannacharya, C., Chan, K.W.K., Chan, S.A., Singh, D., Wei, N., Phoo, W.W., Luo, D., Lescar, J., Vasudevan, S.G.
Deposit date:2017-03-22
Release date:2017-11-08
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
Nucleic Acids Res., 45, 2017
5XC7
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DENGUE VIRUS 4 NS3 HELICASE D290A MUTANT
Descriptor:NS3 Helicase, GLYCEROL, CHLORIDE ION
Authors:Swarbrick, C.M.D., Basavannacharya, C., Chan, K.W.K., Chan, S.A., Singh, D., Wei, N., Phoo, W.W., Luo, D., Lescar, J., Vasudevan, S.G.
Deposit date:2017-03-22
Release date:2017-11-08
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
Nucleic Acids Res., 45, 2017
3OUO
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
Descriptor:Nucleoprotein, NITRITE ION
Authors:Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
Deposit date:2010-09-15
Release date:2011-05-25
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3OV9
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
Descriptor:Nucleoprotein, NITRITE ION, SODIUM ION
Authors:Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
Deposit date:2010-09-16
Release date:2011-05-25
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
4V0Q
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DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH SAH
Descriptor:NS5 POLYMERASE, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Zhao, Y., Soh, S., Zheng, J., Phoo, W.W., Swaminathan, K., Cornvik, T.C., Lim, S.P., Shi, P.-Y., Lescar, J., Vasudevan, S.G., Luo, D.
Deposit date:2014-09-18
Release date:2015-01-28
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
4V0R
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DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
Descriptor:NS5 POLYMERASE, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Zhao, Y., Soh, S., Zheng, J., Phoo, W.W., Swaminathan, K., Cornvik, T.C., Lim, S.P., Shi, P.-Y., Lescar, J., Vasudevan, S.G., Luo, D.
Deposit date:2014-09-18
Release date:2015-01-28
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
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