2WZQ
Insertion Mutant E173GP174 of the NS3 protease-helicase from dengue virus
Summary for 2WZQ
Entry DOI | 10.2210/pdb2wzq/pdb |
Related | 2VBC |
Descriptor | NS3 PROTEASE-HELICASE, CHLORIDE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | virion, hydrolase, transmembrane, envelope protein, nucleotide-binding, capsid protein, domain mobility, rna replication |
Biological source | DENGUE VIRUS More |
Cellular location | Envelope protein E: Virion membrane; Multi- pass membrane protein: Q2TN89 Q2TN89 |
Total number of polymer chains | 2 |
Total formula weight | 72600.85 |
Authors | Luo, D.,Wei, N.,Doan, D.,Paradkar, P.,Chong, Y.,Davidson, A.,Kotaka, M.,Lescar, J.,Vasudevan, S. (deposition date: 2009-12-02, release date: 2010-04-07, Last modification date: 2023-12-20) |
Primary citation | Luo, D.,Wei, N.,Doan, D.N.,Paradkar, P.N.,Chong, Y.,Davidson, A.D.,Kotaka, M.,Lescar, J.,Vasudevan, S.G. Flexibility between the Protease and Helicase Domains of the Dengue Virus Ns3 Protein Conferred by the Linker Region and its Functional Implications. J.Biol.Chem., 285:18817-, 2010 Cited by PubMed: 20375022DOI: 10.1074/JBC.M109.090936 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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