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2WZQ

Insertion Mutant E173GP174 of the NS3 protease-helicase from dengue virus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NS3 PROTEASE-HELICASEpolymer61969576.31UniProt (Q2TN89)
Pfam (PF00949)
Pfam (PF07652)
Pfam (PF20907)
UniProt (by SIFTS) (Q2YHF0)
DENGUE VIRUS
2B
(C)
NS3 PROTEASE-HELICASEpolymer312897.11UniProt (Q2TN89)
UniProt (by SIFTS) (Q2YHF0)
DENGUE VIRUS
3C
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E
(A)
waterwater18.025Chemie (HOH)
Sequence modifications
A: 1 - 173 (UniProt: Q2TN89)
A: 175 - 619 (UniProt: Q2TN89)
PDBExternal DatabaseDetails
Asp 251Glu 1724conflict
A: 174 - 174 (PDB: 2WZQ)
C: 49 - 66 (UniProt: Q2TN89)
PDBExternal DatabaseDetails
Asn 58Ser 1402conflict
Gly 45-expression tag
Ser 46-expression tag
Ala 47-expression tag
Met 48-expression tag
Gly 67-expression tag
Gly 68-expression tag
Gly 69-expression tag
Gly 70-expression tag
Ser 71-expression tag
Gly 72-expression tag
Gly 73-expression tag
Gly 74-expression tag
Gly 75-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight72473.3
Non-Polymers*Number of molecules2
Total formula weight127.5
All*Total formula weight72600.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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