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2AW2
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BU of 2aw2 by Molmil
Crystal structure of the human BTLA-HVEM complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B and T lymphocyte attenuator, NICKEL (II) ION, ...
Authors:Compaan, D.M, Gonzalez, L.C, Tom, I, Loyet, K.M, Eaton, D, Hymowitz, S.G.
Deposit date:2005-08-31
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Attenuating Lymphocyte Activity: the crystal structure of the BTLA-HVEM complex
J.Biol.Chem., 280, 2005
3G6J
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BU of 3g6j by Molmil
C3b in complex with a C3b specific Fab
Descriptor: CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ...
Authors:Wiesmann, C.
Deposit date:2009-02-06
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
J.Biol.Chem., 284, 2009
6VMK
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BU of 6vmk by Molmil
Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12
Descriptor: Complement factor D, Fab Y49R heavy chain, Fab Y49R light chain, ...
Authors:Wu, P, Harris, S.F, Eigenbrot, C.
Deposit date:2020-01-28
Release date:2021-02-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12
To Be Published
6VVU
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BU of 6vvu by Molmil
Anti-Tryptase fab E104.v1 bound to tryptase
Descriptor: CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ...
Authors:Ultsch, M, Koerber, J.T.
Deposit date:2020-02-18
Release date:2020-12-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge.
Nat Commun, 11, 2020
6O1F
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BU of 6o1f by Molmil
Complex between soybean trypsin inhibitor beta1-tryptase and a humanized fab
Descriptor: 1,2-ETHANEDIOL, Heavy Chain hu31A.v11, Light Chain hu31A.v11, ...
Authors:Ultsch, M.H, Yi, T.
Deposit date:2019-02-19
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell, 179, 2019
5D6C
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BU of 5d6c by Molmil
Structure of 4497 Fab bound to synthetic wall teichoic acid fragment
Descriptor: 4-O-[2-acetamido-2-deoxy-beta-D-glucopyranosyl]-5-O-phosphono-D-ribitol, 4497 antibody IgG1 (VH and CH1), 4497 antibody IgK (VL and CL), ...
Authors:Lupardus, P.J, Fong, R.
Deposit date:2015-08-12
Release date:2015-11-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Novel antibody-antibiotic conjugate eliminates intracellular S. aureus.
Nature, 527, 2015
7U5B
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BU of 7u5b by Molmil
Structure of Human KLK5 bound to anti-KLK5 Fab
Descriptor: Kallikrein-5, SULFATE ION, anti-KLK5 Fab Heavy Chain, ...
Authors:Yin, J, Sudhamsu, J.
Deposit date:2022-03-02
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.371 Å)
Cite:Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Sci Transl Med, 14, 2022
6VMJ
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BU of 6vmj by Molmil
Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12
Descriptor: CITRIC ACID, Complement factor D, Fab20D12 Light Chain, ...
Authors:Wu, P, Harris, S.F, Eigenbrot, C.
Deposit date:2020-01-28
Release date:2021-02-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12
To Be Published
7RCO
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BU of 7rco by Molmil
Crystal structure of human TGF-beta-2 bound to 4A11.V2 Fab
Descriptor: 4A11.V2 Fab Heavy Chain, 4A11.V2 Fab Light Chain, Transforming growth factor beta-2
Authors:Yin, J, Lupardus, P.J, Sudhamsu, J.
Deposit date:2021-07-07
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dramatic activation of an antibody by a single amino acid change in framework.
Sci Rep, 11, 2021

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