Author results

1B8C
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PARVALBUMIN
分子名称:PROTEIN (PARVALBUMIN), MAGNESIUM ION
著者Cates, M.S., Berry, M.B., Ho, E.L., Li, Q., Potter, J.D., Phillips Jr., G.N.
登録日1999-01-29
公開日1999-02-02
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin.
Structure Fold.Des., 7, 1999
1B8L
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CALCIUM-BOUND D51A/E101D/F102W TRIPLE MUTANT OF BETA CARP PARVALBUMIN
分子名称:PROTEIN (PARVALBUMIN), CARBONATE ION, CALCIUM ION
著者Cates, M.S., Berry, M.B., Ho, E., Li, Q., Potter, J.D., Phillips Jr., G.N.
登録日1999-02-01
公開日1999-10-05
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin.
Structure Fold.Des., 7, 1999
1B8R
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PARVALBUMIN
分子名称:PROTEIN (PARVALBUMIN), CALCIUM ION
著者Cates, M.S., Berry, M.B., Ho, E.L., Li, Q., Potter, J.D., Phillips Jr., G.N.
登録日1999-02-02
公開日1999-02-09
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin.
Structure Fold.Des., 7, 1999
1B9A
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PARVALBUMIN (MUTATION;D51A, F102W)
分子名称:PROTEIN (PARVALBUMIN), CALCIUM ION
著者Cates, M.S., Berry, M.B., Ho, E.L., Li, Q., Potter, J.D., Phillips Jr., G.N.
登録日1999-02-10
公開日1999-02-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin.
Structure Fold.Des., 7, 1999
1N94
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ARYL TETRAHYDROPYRIDINE INHBITORS OF FARNESYLTRANSFERASE: GLYCINE, PHENYLALANINE AND HISTIDINE DERIVATES
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, ...
著者Gwaltney II, S.L., O'Connor, S.J., Nelson, L.T., Sullivan, G.M., Imade, H., Wang, W., Hasvold, L., Li, Q., Cohen, J., Gu, W.Z.
登録日2002-11-22
公開日2003-01-07
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives.
Bioorg.Med.Chem.Lett., 13, 2003
1N95
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ARYL TETRAHYDROPHYRIDINE INHBITORS OF FARNESYLTRANFERASE: GLYCINE, PHENYLALANINE AND HISTIDINE DERIVATIVES
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Gwaltney II, S.L., O'Conner, S.J., Nelson, L.T., Sullivan, G.M., Imade, H., Wang, W., Hasvold, L., Li, Q., Cohen, J., Gu, W.Z.
登録日2002-11-22
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives.
Bioorg.Med.Chem.Lett., 13, 2003
1N9A
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FARNESYLTRANSFERASE COMPLEX WITH TETRAHYDROPYRIDINE INHIBITORS
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Gwaltney II, S.L., O'Conner, S.J., Nelson, L.T., Sullivan, G.M., Imade, H., Wang, W., Hasvold, L., Li, Q., Cohen, J., Gu, W.Z.
登録日2002-11-22
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency.
Bioorg.Med.Chem.Lett., 13, 2003
1NI1
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IMIDAZOLE AND CYANOPHENYL FARNESYL TRANSFERASE INHIBITORS
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Tong, Y., Lin, N.H., Wang, L., Hasvold, L., Wang, W., Leonard, N., Li, T., Li, Q., Cohen, J., Gu, W.Z., Zhang, H., Stoll, V., Bauch, J., Marsh, K., Rosenberg, S.H., Sham, H.L.
登録日2002-12-20
公開日2004-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
Bioorg.Med.Chem.Lett., 13, 2003
1OR5
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SOLUTION STRUCTURE OF THE HOLO-FORM OF THE FRENOLICIN ACYL CARRIER PROTEIN, MINIMIZED MEAN STRUCTURE
分子名称:acyl carrier protein
著者Li, Q., Khosla, C., Puglisi, J., Liu, C.W.
登録日2003-03-11
公開日2003-07-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure and Backbone Dynamics of the Holo Form of the Frenolicin Acyl Carrier Protein
Biochemistry, 42, 2003
1X81
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FARNESYL TRANSFERASE STRUCTURE OF JANSEN COMPOUND
分子名称:Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Li, Q., Claiborne, A., Li, T., Hasvold, L., Stoll, V.S., Muchmore, S., Jakob, C.G., Gu, W., Cohen, J., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L.
登録日2004-08-16
公開日2004-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
1ZCM
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HUMAN CALPAIN PROTEASE CORE INHIBITED BY ZLLYCH2F
分子名称:Calpain 1, large [catalytic] subunit, CALCIUM ION, ...
著者Li, Q., Hanzlik, R.P., Weaver, R.F., Schonbrunn, E.
登録日2005-04-12
公開日2006-01-31
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core
Biochemistry, 45, 2006
2F7E
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PKA COMPLEXED WITH (S)-2-(1H-INDOL-3-YL)-1-(5-ISOQUINOLIN-6-YL-PYRIDIN-3-YLOXYMETHYL-ETYLAMINE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, PKI inhibitory peptide, ...
著者Stoll, V.S.
登録日2005-11-30
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer.
Bioorg.Med.Chem.Lett., 16, 2006
2F7X
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PROTEIN KINASE A BOUND TO (S)-2-(1H-INDOL-3-YL)-1-[5-((E)-2-PYRIDIN-4-YL-VINYL)-PYRIDIN-3-YLOXYMETHYL]-ETHYLAMINE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, PKI, ...
著者Li, Q., Li, T., Zhu, G.D., Gong, J., Claibone, A., Dalton, C., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Bauch, J.L., Marsh, K.C., Bouska, J.J., Arries, S., De Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L.
登録日2005-12-01
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 16, 2006
2F7Z
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PROTEIN KINASE A BOUND TO (R)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, PKI, ...
著者Li, Q., Woods, K.W., Thomas, S., Zhu, G.D., Packard, G., Fisher, J., Li, T., Gong, J., Dinges, J., Song, X., Abrams, J., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Des Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L.
登録日2005-12-01
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer.
Bioorg.Med.Chem.Lett., 16, 2006
2GHG
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H-CHK1 COMPLEXED WITH A431994
分子名称:Serine/threonine-protein kinase Chk1, 5-{5-[(S)-2-AMINO-3-(1H-INDOL-3-YL)-PROPOXYL]-PYRIDIN-3-YL}-3-[1-(1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE
著者Park, C.
登録日2006-03-27
公開日2007-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers.
Bioorg.Med.Chem.Lett., 16, 2006
2I1J
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MOESIN FROM SPODOPTERA FRUGIPERDA AT 2.1 ANGSTROMS RESOLUTION
分子名称:Moesin, CHLORIDE ION, UREA, ...
著者Li, Q., Nance, M.R., Tesmer, J.J.G.
登録日2006-08-14
公開日2006-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2I1K
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MOESIN FROM SPODOPTERA FRUGIPERDA REVEALS THE COILED-COIL DOMAIN AT 3.0 ANGSTROM RESOLUTION
分子名称:Moesin, CHLORIDE ION, UREA, ...
著者Nance, M.R., Tesmer, J.J.G.
登録日2006-08-14
公開日2006-12-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2KGL
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NMR SOLUTION STRUCTURE OF MESD
分子名称:Mesoderm development candidate 2
著者Chen, J., Wang, J.
登録日2009-03-12
公開日2010-03-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6.
Structure, 19, 2011
2KMI
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MESD(12-155), THE CORE STRUCTURAL DOMAIN OF MESD THAT IS ESSENTIAL FOR PROPER FOLDING OF LRP5/6
分子名称:Mesoderm development candidate 2
著者Chen, J., Wang, J.
登録日2009-07-28
公開日2010-06-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure note: solution structure of the core domain of MESD that is essential for proper folding of LRP5/6.
J.Biomol.Nmr, 47, 2010
2L4R
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NMR SOLUTION STRUCTURE OF THE N-TERMINAL PAS DOMAIN OF HERG
分子名称:Potassium voltage-gated channel subfamily H member 2
著者Gayen, N., Li, Q., Chen, A.S., Huang, Q., Raida, M., Kang, C.
登録日2010-10-13
公開日2010-12-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR solution structure of the N-terminal domain of hERG and its interaction with the S4-S5 linker.
Biochem.Biophys.Res.Commun., 403, 2010
2L7B
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NMR STRUCTURE OF FULL LENGTH APOE3
分子名称:Apolipoprotein E
著者Chen, J., Wang, J.
登録日2010-12-07
公開日2011-08-03
最終更新日2011-09-21
実験手法SOLUTION NMR
主引用文献Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions.
Proc.Natl.Acad.Sci.USA, 108, 2011
2LH0
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NMR STRUCTURE OF THE HISTONE-INTERACTING N-TERMINAL HOMODIMERIC REGION OF RTT106
分子名称:Histone chaperone RTT106
著者Hu, Q., Cui, G., Mer, G.
登録日2011-08-04
公開日2012-02-01
最終更新日2012-03-07
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
2MFR
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SOLUTION STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE INSULIN RECEPTOR IN MICELLES
分子名称:Insulin receptor
著者Li, Q., Wong, Y.L., Kang, C.
登録日2013-10-20
公開日2014-04-02
実験手法SOLUTION NMR
主引用文献Solution structure of the transmembrane domain of the insulin receptor in detergent micelles
Biochim.Biophys.Acta, 1838, 2014
2MHF
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SOLUTION STRUCTURE OF THE CYCLIC-NUCLEOTIDE BINDING HOMOLOGY DOMAIN OF A KCNH CHANNEL
分子名称:Uncharacterized protein
著者Li, Q., Ng, H.
登録日2013-11-21
公開日2014-04-02
実験手法SOLUTION NMR
主引用文献Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
J.Struct.Biol., 2014
2MQW
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SOLUTION STRUCTURE OF A PROTEASOME RELATED SUBUNIT N TERMINAL DOMAIN
分子名称:26S proteasome regulatory subunit RPN9
著者Wu, Y., Hu, Y., Jin, C.
登録日2014-06-30
公開日2015-02-04
最終更新日2017-04-12
実験手法SOLUTION NMR
主引用文献Solution structure of yeast Rpn9: insights into proteasome lid assembly.
J. Biol. Chem., 290, 2015