1BNK
| HUMAN 3-METHYLADENINE DNA GLYCOSYLASE COMPLEXED TO DNA | Descriptor: | DNA (5'-D(*GP*AP*CP*AP*TP*GP*YRRP*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), PROTEIN (3-METHYLADENINE DNA GLYCOSYLASE) | Authors: | Lau, A.Y, Schaerer, O.D, Samson, L, Verdine, G.L, Ellenberger, T. | Deposit date: | 1998-07-29 | Release date: | 1998-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell(Cambridge,Mass.), 95, 1998
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1EWN
| CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH 1,N6-ETHENOADENINE-DNA | Descriptor: | 3-METHYL-ADENINE DNA GLYCOSYLASE, DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDA)P*TP*TP*GP*CP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), ... | Authors: | Lau, A.Y, Wyatt, M.D, Glassner, B.J, Samson, L.D, Ellenberger, T. | Deposit date: | 2000-04-26 | Release date: | 2000-12-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc.Natl.Acad.Sci.USA, 97, 2000
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1F4R
| CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH 1,N6-ETHENOADENINE-DNA | Descriptor: | 3-METHYL-ADENINE DNA GLYCOSYLASE, DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDA)P*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), ... | Authors: | Lau, A.Y, Wyatt, M.D, Glassner, B.J, Samson, L.D, Ellenberger, T. | Deposit date: | 2000-06-08 | Release date: | 2000-12-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc.Natl.Acad.Sci.USA, 97, 2000
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1F6O
| CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH DNA | Descriptor: | 3-METHYL-ADENINE DNA GLYCOSYLASE, DNA (5'-D(*GP*AP*CP*AP*TP*GP*(YRR)P*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), ... | Authors: | Lau, A.Y, Wyatt, M.D, Glassner, B.J, Samson, L.D, Ellenberger, T. | Deposit date: | 2000-06-22 | Release date: | 2000-12-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc.Natl.Acad.Sci.USA, 97, 2000
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4L17
| GluA2-L483Y-A665C ligand-binding domain in complex with the antagonist DNQX | Descriptor: | 6,7-DINITROQUINOXALINE-2,3-DIONE, Glutamate receptor 2, SULFATE ION | Authors: | Lau, A.Y, Blachowicz, L, Roux, B. | Deposit date: | 2013-06-02 | Release date: | 2013-08-14 | Last modified: | 2017-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A conformational intermediate in glutamate receptor activation. Neuron, 79, 2013
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4YU0
| Crystal structure of a tetramer of GluA2 TR mutant ligand binding domains bound with glutamate at 1.26 Angstrom resolution | Descriptor: | DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ... | Authors: | Chebli, M, Salazar, H, Baranovic, J, Carbone, A.L, Ghisi, V, Faelber, K, Lau, A.Y, Daumke, O, Plested, A.J.R. | Deposit date: | 2015-03-18 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Crystal structure of the tetrameric GluA2 ligand-binding domain in complex with glutamate at 1.26 Angstroms resolution To Be Published
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4Z0I
| Crystal structure of a tetramer of GluA2 ligand binding domains bound with glutamate at 1.45 Angstrom resolution | Descriptor: | DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ... | Authors: | Baranovic, J, Chebli, M, Salazar, H, Carbone, A.L, Ghisi, V, Faelber, K, Lau, A.Y, Daumke, O, Plested, A.J.R. | Deposit date: | 2015-03-26 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of the tetrameric wt GluA2 ligand-binding domain bound to glutamate at 1.45 Angstroms resolution To Be Published
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4KCD
| Crystal Structure of the NMDA Receptor GluN3A Ligand Binding Domain Apo State | Descriptor: | GLYCEROL, Glutamate receptor ionotropic, NMDA 3A | Authors: | Yao, Y, Lau, A.Y, Mayer, M.L. | Deposit date: | 2013-04-24 | Release date: | 2013-07-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics. Structure, 21, 2013
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4KCC
| Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State | Descriptor: | Glutamate receptor ionotropic, NMDA 1, PHOSPHATE ION | Authors: | Berger, A.J, Lau, A.Y, Mayer, M.L. | Deposit date: | 2013-04-24 | Release date: | 2013-07-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.894 Å) | Cite: | Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics. Structure, 21, 2013
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8VJ7
| GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 2 | Descriptor: | 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2 | Authors: | Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C. | Deposit date: | 2024-01-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.85 Å) | Cite: | Allosteric competition and inhibition in AMPA receptors. Nat.Struct.Mol.Biol., 2024
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8VJ6
| GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 1 | Descriptor: | 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, Isoform Flip of Glutamate receptor 2 | Authors: | Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C. | Deposit date: | 2024-01-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Allosteric competition and inhibition in AMPA receptors. Nat.Struct.Mol.Biol., 2024
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7K3R
| Cryo-EM structure of AIM2-PYD filament | Descriptor: | Interferon-inducible protein AIM2 | Authors: | Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H. | Deposit date: | 2020-09-12 | Release date: | 2021-05-26 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome. Nat Commun, 12, 2021
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7TE9
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7TES
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7TE4
| Crystal structure of Fab2 anti-GluN2B antibody | Descriptor: | Fab anti-GluN2B antibody, heavy chain, Fab2 anti-GluN2B antibody, ... | Authors: | Tajima, N, Furukawa, H. | Deposit date: | 2022-01-04 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.456 Å) | Cite: | Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
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7TEB
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7TE6
| Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody | Descriptor: | Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... | Authors: | Regan, M, Tajima, N, Furukawa, H. | Deposit date: | 2022-01-04 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (4.55 Å) | Cite: | Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
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7TER
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7TEE
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7TET
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7TEQ
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5CMB
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5CMC
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