1EWN

CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH 1,N6-ETHENOADENINE-DNA

Summary for 1EWN

Related1BNK
DescriptorDNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDA)P*TP*TP*GP*CP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), 3-METHYL-ADENINE DNA GLYCOSYLASE, ... (5 entities in total)
Functional Keywordsdna repair, glycosylase, aag, anpg, mpg, 3-methyladenine dna glycosylase, hydrolase-dna complex, hydrolase/dna
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total molecular weight31683.75
Authors
Lau, A.Y.,Wyatt, M.D.,Glassner, B.J.,Samson, L.D.,Ellenberger, T. (deposition date: 2000-04-26, release date: 2000-12-11, Last modification date: 2011-07-13)
Primary citation
Lau, A.Y.,Wyatt, M.D.,Glassner, B.J.,Samson, L.D.,Ellenberger, T.
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG.
Proc.Natl.Acad.Sci.USA, 97:13573-13578, 2000
PubMed: 11106395 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.97.25.13573
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers13 1.5% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25