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2BAP
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CRYSTAL STRUCTURE OF THE N-TERMINAL MDIA1 ARMADILLO REPEAT REGION AND DIMERISATION DOMAIN IN COMPLEX WITH THE MDIA1 AUTOREGULATORY DOMAIN (DAD)
Descriptor:Diaphanous protein homolog 1
Authors:Lammers, M., Rose, R., Scrima, A., Wittinghofer, A.
Deposit date:2005-10-14
Release date:2006-03-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The regulation of mDia1 by autoinhibition and its release by Rho*GTP.
Embo J., 24, 2005
2X25
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FREE ACETYL-CYPA ORTHORHOMBIC FORM
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-11
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerization.
Nat.Chem.Biol., 6, 2010
2X2A
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FREE ACETYL-CYPA TRIGONAL FORM
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, GLYCEROL, SULFATE ION
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-12
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerization.
Nat.Chem.Biol., 6, 2010
2X2C
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ACETYL-CYPA:CYCLOSPORINE COMPLEX
Descriptor:CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-12
Release date:2010-03-23
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation
Nat.Chem.Biol., 6, 2010
2X2D
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ACETYL-CYPA:HIV-1 N-TERM CAPSID DOMAIN COMPLEX
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, CAPSID PROTEIN P24
Authors:Lammers, M., Neumann, H., Chin, J.W., James, L.C.
Deposit date:2010-01-12
Release date:2010-03-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation
Nat.Chem.Biol., 6, 2010
3EG5
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CRYSTAL STRUCTURE OF MDIA1-TSH GBD-FH3 IN COMPLEX WITH CDC42-GMPPNP
Descriptor:Cell division control protein 42 homolog, Protein diaphanous homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Lammers, M., Meyer, S., Kuehlmann, D., Wittinghofer, A.
Deposit date:2008-09-10
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Specificity of Interactions between mDia Isoforms and Rho Proteins
J.Biol.Chem., 283, 2008
1Z2C
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CRYSTAL STRUCTURE OF MDIA1 GBD-FH3 IN COMPLEX WITH RHOC-GMPPNP
Descriptor:Rho-related GTP-binding protein RhoC, Diaphanous protein homolog 1, MAGNESIUM ION, ...
Authors:Rose, R., Weyand, M., Lammers, M., Ishizaki, T., Ahmadian, M.R., Wittinghofer, A.
Deposit date:2005-03-08
Release date:2005-05-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
Nature, 435, 2005
5FR2
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FARNESYLATED RHOA-GDP IN COMPLEX WITH RHOGDI-ALPHA, LYSINE ACETYLATED AT K178
Descriptor:TRANSFORMING PROTEIN RHOA, RHO GDP-DISSOCIATION INHIBITOR 1, FARNESYL, ...
Authors:Kuhlmann, N., Wroblowski, S., Knyphausen, P., de Boor, S., Brenig, J., Zienert, A.Y., Meyer-Teschendorf, K., Praefcke, G.J.K., Nolte, H., Krueger, M., Schacherl, M., Baumann, U., James, L.C., Chin, J.W., Lammers, M.
Deposit date:2015-12-15
Release date:2016-01-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.
J.Biol.Chem., 291, 2016
5FYQ
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SIRT2 IN COMPLEX WITH A 13-MER TRIFLUOROACETYLATED RAN PEPTIDE
Descriptor:NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, RAN AA 31-43, SULFATE ION, ...
Authors:Knyphausen, P., de Boor, S., Scislowski, L., Extra, A., Baldus, L., Schacherl, M., Baumann, U., Neundorf, I., Lammers, M.
Deposit date:2016-03-09
Release date:2016-05-25
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Insights Into Lysine-Deacetylation of Natively Folded Substrate Proteins by Sirtuins.
J.Biol.Chem., 291, 2016
2WLV
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STRUCTURE OF THE N-TERMINAL CAPSID DOMAIN OF HIV-2
Descriptor:GAG POLYPROTEIN
Authors:Price, A.J., Marzetta, F., Lammers, M., Ylinen, L.M.J., Schaller, T., Wilson, S.J., Towers, G.J., James, L.C.
Deposit date:2009-06-26
Release date:2009-09-22
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Active Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp
Nat.Struct.Mol.Biol., 16, 2009
2WLW
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STRUCTURE OF THE N-TERMINAL CAPSID DOMAIN OF HIV-2
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:Price, A.J., Marzetta, F., Lammers, M., Ylinen, L.M.J., Schaller, T., Wilson, S.J., Towers, G.J., James, L.C.
Deposit date:2009-06-26
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Active Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp
Nat.Struct.Mol.Biol., 16, 2009
4UWX
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STRUCTURE OF LIPRIN-ALPHA3 IN COMPLEX WITH MDIA1 DIAPHANOUS- INHIBITORY DOMAIN
Descriptor:PROTEIN DIAPHANOUS HOMOLOG 1, LIPRIN-ALPHA-3, NICKEL (II) ION, ...
Authors:Brenig, J., de Boor, S., Knyphausen, P., Kuhlmann, N., Wroblowski, S., Baldus, L., Scislowski, L., Artz, O., Trauschies, P., Baumann, U., Neundorf, I., Lammers, M.
Deposit date:2014-08-15
Release date:2015-05-06
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and Biochemical Basis for the Inhibitory Effect of Liprin-Alpha3 on Mouse Diaphanous 1 (Mdia1) Function.
J.Biol.Chem., 290, 2015
5FR1
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DOUBLE ACETYLATED RHOGDI-ALPHA IN COMPLEX WITH RHOA-GDP
Descriptor:TRANSFORMING PROTEIN RHOA, RHO GDP-DISSOCIATION INHIBITOR 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Kuhlmann, N., Wroblowski, S., Lammers, M.
Deposit date:2015-12-15
Release date:2016-01-13
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Rhogdi Alpha Acetylation at K127 and K141 Affects Binding Towards Non-Prenylated Rhoa.
Biochemistry, 55, 2016
6Y9K
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ESTERASE EST8 WITH TRANSACYLASE ACTIVITY
Descriptor:Esterase Est8
Authors:Palm, G.J., Lammers, M., Berndt, L.
Deposit date:2020-03-09
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Sequence-Based Prediction of Promiscuous Acyltransferase Activity in Hydrolases.
Angew.Chem.Int.Ed.Engl., 59, 2020
167518
PDB entries from 2020-08-12