5FYQ

Sirt2 in complex with a 13-mer trifluoroacetylated Ran peptide

Summary for 5FYQ

Entry DOI	10.2210/pdb5fyq/pdb
Descriptor	NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, RAN AA 31-43, SULFATE ION, ... (5 entities in total)
Functional Keywords	hydrolase, sirtuin, kdac, lysine-deacetylase, lysine-acetylation, genetic-code expansion
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus. Isoform 1: Cytoplasm . Isoform 2: Cytoplasm . Isoform 5: Cytoplasm : Q8IXJ6 Nucleus : P62826
Total number of polymer chains	4
Total formula weight	83835.91
Authors	Knyphausen, P.,de Boor, S.,Scislowski, L.,Extra, A.,Baldus, L.,Schacherl, M.,Baumann, U.,Neundorf, I.,Lammers, M. (deposition date: 2016-03-09, release date: 2016-05-25, Last modification date: 2024-01-10)
Primary citation	Knyphausen, P.,De Boor, S.,Kuhlmann, N.,Scislowski, L.,Extra, A.,Baldus, L.,Schacherl, M.,Baumann, U.,Neundorf, I.,Lammers, M. Insights Into Lysine-Deacetylation of Natively Folded Substrate Proteins by Sirtuins. J.Biol.Chem., 291:14677-, 2016 Cited by PubMed: 27226597 DOI: 10.1074/JBC.M116.726307 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation