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5FYQ

Sirt2 in complex with a 13-mer trifluoroacetylated Ran peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2polymer36040160.72UniProt (Q8IXJ6)
Pfam (PF02146)
HOMO SAPIENS (HUMAN)REGULATORY PROTEIN SIR2 HOMOLOG 2, SIR2-LIKE PROTEIN 2
2C, D
(C, D)
RAN AA 31-43polymer131595.72UniProt (P62826)HOMO SAPIENS
3E, G
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
4F, H
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
5I, J, K
(A, B, D)
waterwater18.0176Chemie (HOH)
Sequence modifications
A, B: 1 - 356 (UniProt: Q8IXJ6)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
Gly -1-expression tag
Met 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight83513.0
Non-Polymers*Number of molecules4
Total formula weight322.9
All*Total formula weight83835.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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