7QE8

Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)

Summary for 7QE8

• Entry DOI: 10.2210/pdb7qe8/pdb
• Related: 7QE9
• Descriptor: Trypsin-1, Serine protease inhibitor Kazal-type 1, SULFATE ION, ... (4 entities in total)
• Functional Keywords: try1, spink1, serine protease, protease-inhibitor complex, catalytic triad, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 61038.70

Authors

Nagel, F.,Palm, G.J.,Delcea, M.,Lammers, M. (deposition date: 2021-12-01, release date: 2022-03-30, Last modification date: 2024-05-01)

• Primary citation: Nagel, F.,Palm, G.J.,Geist, N.,McDonnell, T.C.R.,Susemihl, A.,Girbardt, B.,Mayerle, J.,Lerch, M.M.,Lammers, M.,Delcea, M.; Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.; Int J Mol Sci, 23:-, 2022; PubMed: 35408828; DOI: 10.3390/ijms23073468

Experimental method

X-RAY DIFFRACTION (2.9 Å)