7QE8
Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Trypsin-1 | polymer | 224 | 24121.2 | 2 | UniProt (P07477) Pfam (PF00089) | Homo sapiens (human) | Beta-trypsin,Cationic trypsinogen,Serine protease 1,Trypsin I |
| 2 | C, D (C, D) | Serine protease inhibitor Kazal-type 1 | polymer | 56 | 6254.1 | 2 | UniProt (P00995) Pfam (PF00050) | Homo sapiens (human) | Pancreatic secretory trypsin inhibitor,Tumor-associated trypsin inhibitor,TATI |
| 3 | E, F, G (B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | H (B) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 247 (UniProt: P07477)
| PDB | External Database | Details |
|---|---|---|
| Ala 200 | Ser 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60750.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 61038.7 |
