Author results

1A1P
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COMPSTATIN, NMR, 21 STRUCTURES
Descriptor:COMPSTATIN
Authors:Morikis, D., Assa-Munt, N., Sahu, A., Lambris, J.D.
Deposit date:1997-12-12
Release date:1998-04-08
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of Compstatin, a potent complement inhibitor.
Protein Sci., 7, 1998
2I07
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HUMAN COMPLEMENT COMPONENT C3B
Descriptor:Complement C3b, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
Authors:Janssen, B.J.C., Christodoulidou, A., McCarthy, A., Lambris, J.D., Gros, P.
Deposit date:2006-08-10
Release date:2006-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
2QKI
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HUMAN C3C IN COMPLEX WITH THE INHIBITOR COMPSTATIN
Descriptor:Complement C3, compstatin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Janssen, B.J.C., Halff, E.F., Lambris, J.D., Gros, P.
Deposit date:2007-07-11
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
J.Biol.Chem., 282, 2007
2XW9
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CRYSTAL STRUCTURE OF COMPLEMENT FACTOR D MUTANT S183A
Descriptor:COMPLEMENT FACTOR D, GLYCEROL
Authors:Forneris, F., Ricklin, D., Wu, J., Tzekou, A., Wallace, R.S., Lambris, J.D., Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWA
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CRYSTAL STRUCTURE OF COMPLEMENT FACTOR D MUTANT R202A
Descriptor:COMPLEMENT FACTOR D, GLYCEROL
Authors:Forneris, F., Ricklin, D., Wu, J., Tzekou, A., Wallace, R.S., Lambris, J.D., Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWB
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CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTORS B AND D
Descriptor:COMPLEMENT C3B BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR B, ...
Authors:Forneris, F., Ricklin, D., Wu, J., Tzekou, A., Wallace, R.S., Lambris, J.D., Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWJ
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CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTOR B
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT FACTOR B, ...
Authors:Forneris, F., Ricklin, D., Wu, J., Tzekou, A., Wallace, R.S., Lambris, J.D., Gros, P.
Deposit date:2010-11-04
Release date:2011-01-12
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2GOM
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CRYSTAL STRUCTURE OF EFB-C FROM STAPHYLOCOCCUS AUREUS
Descriptor:Fibrinogen-binding protein
Authors:Hammel, M., Geisbrecht, B.V.
Deposit date:2006-04-13
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A structural basis for complement inhibition by Staphylococcus aureus.
Nat.Immunol., 8, 2007
2GOX
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CRYSTAL STRUCTURE OF EFB-C / C3D COMPLEX
Descriptor:Complement C3, Fibrinogen-binding protein
Authors:Hammel, M., Geisbrecht, B.V.
Deposit date:2006-04-14
Release date:2007-03-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A structural basis for complement inhibition by Staphylococcus aureus.
Nat.Immunol., 8, 2007
2NOJ
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CRYSTAL STRUCTURE OF EHP / C3D COMPLEX
Descriptor:Complement C3, Efb homologous protein
Authors:Hammel, M., Geisbrecht, B.V.
Deposit date:2006-10-25
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Characterization of Ehp, a Secreted Complement Inhibitory Protein from Staphylococcus aureus.
J.Biol.Chem., 282, 2007
2WII
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COMPLEMENT C3B IN COMPLEX WITH FACTOR H DOMAINS 1-4
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR H, ...
Authors:Wu, J., Janssen, B.J.C., Gros, P.
Deposit date:2009-05-12
Release date:2009-06-09
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
2WIN
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C3 CONVERTASE (C3BBB) STABILIZED BY SCIN
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR B, ...
Authors:Wu, J., Janssen, B.J., Gros, P.
Deposit date:2009-05-13
Release date:2009-06-09
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat. Immunol., 10, 2009
3D5R
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CRYSTAL STRUCTURE OF EFB-C (N138A) / C3D COMPLEX
Descriptor:Complement C3, Fibrinogen-binding protein
Authors:Geisbrecht, B.V.
Deposit date:2008-05-16
Release date:2008-09-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
3D5S
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CRYSTAL STRUCTURE OF EFB-C (R131A) / C3D COMPLEX
Descriptor:Complement C3, Fibrinogen-binding protein
Authors:Geisbrecht, B.V.
Deposit date:2008-05-16
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
3L3O
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STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT COMPONENT C3C
Descriptor:Complement C3, Staphylococcal complement inhibitor, N-ACETYL-D-GLUCOSAMINE
Authors:Geisbrecht, B.V., Garcia, B.G.
Deposit date:2009-12-17
Release date:2010-08-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.405 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3L5N
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STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT COMPONENT C3B
Descriptor:Complement C3, Staphylococcal complement inhibitor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Geisbrecht, B.V., Garcia, B.L.
Deposit date:2009-12-22
Release date:2010-08-04
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (7.536 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3NMS
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STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) IN COMPLEX WITH HUMAN COMPLEMENT C3C
Descriptor:Complement C3, Staphylococcal complement inhibitor, N-ACETYL-D-GLUCOSAMINE
Authors:Geisbrecht, B.V., Garcia, B.L.
Deposit date:2010-06-22
Release date:2010-08-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3OHX
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MOLECULAR BASIS FOR COMPLEMENT RECOGNITION AND INHIBITION DETERMINED BY CRYSTALLOGRAPHIC STUDIES OF THE STAPHYLOCOCCAL COMPLEMENT INHIBITOR (SCIN) BOUND TO C3C AND C3B
Descriptor:Complement C3, Staphylococcal complement inhibitor, N-ACETYL-D-GLUCOSAMINE
Authors:Geisbrecht, B.V., Garcia, B.L.
Deposit date:2010-08-18
Release date:2010-09-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3T46
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR D (SCIN-D) AT 1.5 ANGSTROM
Descriptor:SCIN-D, SODIUM ION
Authors:Garcia, B.L., Geisbrecht, B.V., Summers, B.J.
Deposit date:2011-07-25
Release date:2011-11-23
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T47
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CRYSTAL STRUCTURE OF TRUNCATED FORM OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR D (SCIN-D) AT 1.3 ANGSTROM
Descriptor:SCIN-D
Authors:Garcia, B.L., Geisbrecht, B.V., Summers, B.J.
Deposit date:2011-07-25
Release date:2011-11-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.301 Å)
Cite:Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T48
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CRYSTAL STRUCTURE OF TRUNCATED FORM OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR D (SCIN-D) AT 1.5 ANGSTROM
Descriptor:SCIN-D
Authors:Garcia, B.L., Geisbrecht, B.V., Summers, B.J.
Deposit date:2011-07-25
Release date:2011-11-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T49
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CRYSTAL STRUCTURE OF TRUNCATED FORM OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR B (SCIN-B) AT 1.5 ANGSTROM
Descriptor:Fibrinogen-binding protein, GLYCEROL, SULFATE ION
Authors:Garcia, B.L., Geisbrecht, B.V., Summers, B.J.
Deposit date:2011-07-25
Release date:2011-11-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
3T4A
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STRUCTURE OF A TRUNCATED FORM OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR B BOUND TO HUMAN C3C AT 3.4 ANGSTROM RESOLUTION
Descriptor:Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ...
Authors:Garcia, B.L., Geisbrecht, B.V., Summers, B.J.
Deposit date:2011-07-25
Release date:2011-11-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
4H6H
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR SCIN-B(4-85)
Descriptor:Fibrinogen-binding protein
Authors:Garcia, B.L., Geisbrecht, B.V.
Deposit date:2012-09-19
Release date:2012-12-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5024 Å)
Cite:A Structurally Dynamic N-terminal Helix Is a Key Functional Determinant in Staphylococcal Complement Inhibitor (SCIN) Proteins.
J.Biol.Chem., 288, 2013
4H6I
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL COMPLEMENT INHIBITOR SCIN-B
Descriptor:Fibrinogen-binding protein
Authors:Garcia, B.L., Geisbrecht, B.V.
Deposit date:2012-09-19
Release date:2012-12-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.091 Å)
Cite:A Structurally Dynamic N-terminal Helix Is a Key Functional Determinant in Staphylococcal Complement Inhibitor (SCIN) Proteins.
J.Biol.Chem., 288, 2013
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