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6N9Y
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ATOMIC STRUCTURE OF NON-STRUCTURAL PROTEIN 1 OF BLUETONGUE VIRUS
Descriptor:Non-structural protein 1
Authors:Kerviel, A., Ge, P., Lai, M., Jih, J., Boyce, M., Zhang, X., Zhou, Z.H., Roy, P.
Deposit date:2018-12-04
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Atomic structure of the translation regulatory protein NS1 of bluetongue virus.
Nat Microbiol, 2019
5T2A
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CRYOEM STRUCTURE OF THE LEISHMANIA DONOVANI 80S RIBOSOME AT 2.9 ANGSTROM RESOLUTION
Descriptor:LSU-alpha, LSU-beta, 5.8S rRNA, ...
Authors:Zhang, X., Lai, M., Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
5T2C
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CRYOEM STRUCTURE OF THE HUMAN RIBOSOME AT 3.6 ANGSTROM RESOLUTION
Descriptor:5S rRNA, 5.8S rRNA, 60S ribosomal protein L8, ...
Authors:Zhang, X., Lai, M., Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
5TC1
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IN SITU STRUCTURES OF THE GENOME AND GENOME-DELIVERY APPARATUS IN SSRNA BACTERIOPHAGE MS2
Descriptor:Capsid protein, Maturation protein, phage MS2 genome
Authors:Dai, X.H., Li, Z.H., Lai, M., Shu, S., Du, Y.S., Zhou, Z.H., Sun, R.
Deposit date:2016-09-13
Release date:2016-12-07
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus.
Nature, 541, 2017
6BP7
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RECOMBINANT MAJOR VAULT PROTEIN [RATTUS NORVEGICUS] STRUCTURE IN SOLUTION: CONFORMATION 2
Descriptor:Major vault protein
Authors:Ding, K., Zhang, X., Mrazek, J., Kickhoefer, V.A., Lai, M., Ng, H.L., Yang, O.O., Rome, L.H., Zhou, Z.H.
Deposit date:2017-11-22
Release date:2018-04-04
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Solution Structures of Engineered Vault Particles.
Structure, 26, 2018
6BP8
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RECOMBINANT MAJOR VAULT PROTEIN [RATTUS NORVEGICUS] STRUCTURE IN SOLUTION: CONFORMATION 1
Descriptor:Major vault protein
Authors:Ding, K., Zhang, X., Mrazek, J., Kickhoefer, V.A., Lai, M., Ng, H.L., Yang, O.O., Rome, L.H., Zhou, Z.H.
Deposit date:2017-11-22
Release date:2018-04-04
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Solution Structures of Engineered Vault Particles.
Structure, 26, 2018
6E10
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PTEX CORE COMPLEX IN THE ENGAGED (EXTENDED) STATE
Descriptor:Heat shock protein 101, Exported protein 2, Translocon component PTEX150, ...
Authors:Ho, C., Lai, M., Zhou, Z.H.
Deposit date:2018-07-08
Release date:2018-08-22
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Malaria parasite translocon structure and mechanism of effector export.
Nature, 561, 2018
6E11
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PTEX CORE COMPLEX IN THE RESETTING (COMPACT) STATE
Descriptor:Unknown (Claw), Heat shock protein 101, Exported protein 2, ...
Authors:Ho, C., Lai, M., Zhou, Z.H.
Deposit date:2018-07-08
Release date:2018-08-22
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Malaria parasite translocon structure and mechanism of effector export.
Nature, 561, 2018
3FKT
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CRYSTAL STRUCTURE OF HUMAN BETA SECRETASE COMPLEXED WITH SPIROPIPERDINE IMINOHYDANTOIN INHIBITOR
Descriptor:Beta-secretase 1, N-(4-{[4-(cyclohexylamino)-1-(3-fluorophenyl)-2-oxo-1,3,8-triazaspiro[4.5]dec-3-en-8-yl]methyl}phenyl)acetamide
Authors:Munshi, S.
Deposit date:2008-12-17
Release date:2009-01-20
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and X-ray Crystallographic Analysis of a Iminohydantoin Inhibitor of beta-Secretase
J.Med.Chem., 51, 2008
6CCY
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CRYSTAL STRUCTURE OF AKT1 IN COMPLEX WITH A SELECTIVE INHIBITOR
Descriptor:RAC-alpha serine/threonine-protein kinase,PIFtide, (5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
Authors:Wang, Y., Stout, S.
Deposit date:2018-02-07
Release date:2018-05-02
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT.
Bioorg. Med. Chem. Lett., 28, 2018
5OSG
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STRUCTURE OF KSRP IN CONTEXT OF LEISHMANIA DONOVANI 80S
Descriptor:RNA binding protein, putative, 18S rRNA, ...
Authors:Brito Querido, J., Mancera-Martinez, E., Vicens, Q., Bochler, A., Chicher, J., Simonetti, A., Hashem, Y.
Deposit date:2017-08-17
Release date:2017-11-15
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Structure, 25, 2017