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1KGY
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CRYSTAL STRUCTURE OF THE EPHB2-EPHRINB2 COMPLEX
Descriptor:EPHRIN TYPE-B RECEPTOR 2, EPHRIN-B2
Authors:Himanen, J.P., Rajashankar, K.R., Lackmann, M., Cowan, C.A., Henkemeyer, M., Nikolov, D.B.
Deposit date:2001-11-28
Release date:2002-05-28
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an Eph receptor-ephrin complex.
Nature, 414, 2001
1SHW
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EPHB2 / EPHRINA5 COMPLEX STRUCTURE
Descriptor:Ephrin-A5, Ephrin type-B receptor 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Himanen, J.P., Chumley, M.J., Lackmann, M., Li, C., Barton, W.A., Jeffrey, P.D., Vearing, C., Geleick, D., Feldheim, D.A., Boyd, A.W.
Deposit date:2004-02-26
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7, 2004
1CWW
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SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1
Descriptor:APOPTOTIC PROTEASE ACTIVATING FACTOR 1
Authors:Day, C.L., Dupont, C., Lackmann, M., Vaux, D.L., Hinds, M.G.
Deposit date:1999-08-26
Release date:2000-01-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1.
Cell Death Differ., 6, 1999
1O0L
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THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY
Descriptor:Apoptosis regulator Bcl-W
Authors:Hinds, M.G., Lackmann, M., Skea, G.L., Harrison, P.J., Huang, D.C.S., Day, C.L.
Deposit date:2003-02-22
Release date:2003-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity
Embo J., 22, 2003
2AO7
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ADAM10 DISINTEGRIN AND CYSTEINE- RICH DOMAIN
Descriptor:ADAM 10, SULFATE ION
Authors:Janes, P.W., Saha, N., Barton, W.A., Kolev, M.V., Wimmer-Kleikamp, S.H., Nievergall, E., Blobel, C.P., Himanen, J.-P., Lackmann, M., Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
3MX0
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CRYSTAL STRUCTURE OF EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN-A5
Descriptor:Ephrin type-A receptor 2, Ephrin-A5, N-ACETYL-D-GLUCOSAMINE
Authors:Himanen, J.P., Yermekbayeva, L., Janes, P.W., Walker, J.R., Xu, K., Atapattu, L., Rajashankar, K.R., Mensinga, A., Lackmann, M., Nikolov, D.B., Dhe-Paganon, S.
Deposit date:2010-05-06
Release date:2010-06-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3FL7
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CRYSTAL STRUCTURE OF THE HUMAN EPHRIN A2 ECTODOMAIN
Descriptor:Ephrin receptor, SODIUM ION, CHLORIDE ION, ...
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-12-18
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
1SHX
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EPHRIN A5 LIGAND STRUCTURE
Descriptor:Ephrin-A5, N-ACETYL-D-GLUCOSAMINE
Authors:Himanen, J.P., Barton, W.A., Nikolov, D.B., Jeffrey, P.D.
Deposit date:2004-02-26
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
J.Biol.Chem., 280, 2005
3CZU
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CRYSTAL STRUCTURE OF THE HUMAN EPHRIN A2- EPHRIN A1 COMPLEX
Descriptor:Ephrin type-A receptor 2, Ephrin-A1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Wikstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-04-30
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
5L0Q
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN ADAM10 D+C DOMAIN AND A CONFORMATION SPECIFIC MAB 8C7.
Descriptor:Disintegrin and metalloproteinase domain-containing protein 10, mAb 8C7 light chain, mAb 8C7 heavy chain, ...
Authors:Xu, K., Saha, N., Nikolov, D.B.
Deposit date:2016-07-28
Release date:2016-11-09
Method:X-RAY DIFFRACTION (2.759 Å)
Cite:An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016
3C8X
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE
Descriptor:Ephrin type-A receptor 2
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-02-14
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MBW
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CRYSTAL STRUCTURE OF THE HUMAN EPHRIN A2 LBD AND CRD DOMAINS IN COMPLEX WITH EPHRIN A1
Descriptor:Ephrin type-A receptor 2, Ephrin-A1, UNKNOWN ATOM OR ION, ...
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2010-03-26
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3GXU
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CRYSTAL STRUCTURE OF EPH RECEPTOR AND EPHRIN COMPLEX
Descriptor:Ephrin type-A receptor 4, Ephrin-B2
Authors:Qin, H.N., Song, J.X.
Deposit date:2009-04-03
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity
J.Biol.Chem., 2009