Author results

4X34
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CRYSTAL STRUCTURE OF THE 53BP1 TANDEM TUDOR DOMAIN IN COMPLEX WITH P53K381ACK382ME2
Descriptor:Tumor suppressor p53-binding protein 1, THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS
Authors:Tong, Q., Kutateladze, T.G.
Deposit date:2014-11-27
Release date:2015-03-04
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
6MIL
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CRYSTAL STRUCTURE OF AF9 YEATS DOMAIN IN COMPLEX WITH HISTONE H3K9BU
Descriptor:Protein AF-9, Histone H3K9bu, DI(HYDROXYETHYL)ETHER, ...
Authors:Vann, K.R., Klein, B.J., Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIM
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CRYSTAL STRUCTURE OF AF9 YEATS DOMAIN Y78W MUTANT IN COMPLEX WITH HISTONE H3K9CR
Descriptor:Protein AF-9, Histone H3K9cr
Authors:Vann, K.R., Klein, B.J., Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Method:X-RAY DIFFRACTION (2.525 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIN
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CRYSTAL STRUCTURE OF TAF14 YEATS DOMAIN G82A MUTANT IN COMPLEX WITH HISTONE H3K9CR
Descriptor:Transcription initiation factor TFIID subunit 14, Histone H3K9cr
Authors:Klein, B.J., Andrews, F.H., Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIO
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CRYSTAL STRUCTURE OF TAF14 YEATS DOMAIN IN COMPLEX WITH HISTONE H3K9PR
Descriptor:Transcription initiation factor TFIID subunit 14, Histone H3K9pr
Authors:Klein, B.J., Andrews, F.H., Vann, K.R., Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIP
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CRYSTAL STRUCTURE OF TAF14 YEATS DOMAIN G82A MUTANT
Descriptor:Transcription initiation factor TFIID subunit 14, DI(HYDROXYETHYL)ETHER
Authors:Klein, B.J., Andrews, F.H., Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIQ
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CRYSTAL STRUCTURE OF TAF14 YEATS DOMAIN IN COMPLEX WITH HISTONE H3K9BU
Descriptor:Transcription initiation factor TFIID subunit 14, Histone H3K9bu
Authors:Klein, B.J., Andrews, F.H., Vann, K.R., Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
1R48
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SOLUTION STRUCTURE OF THE C-TERMINAL CYTOPLASMIC DOMAIN RESIDUES 468-497 OF ESCHERICHIA COLI PROTEIN PROP
Descriptor:Proline/betaine transporter
Authors:Zoetewey, D.L., Tripet, B.P., Kutateladze, T.G., Overduin, M.J., Wood, J.M., Hodges, R.S.
Deposit date:2003-10-03
Release date:2003-12-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
2G6Q
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CRYSTAL STRUCTURE OF ING2 PHD FINGER IN COMPLEX WITH H3K4ME3 PEPTIDE
Descriptor:Inhibitor of growth protein 2, H3K4Me3 peptide, ZINC ION
Authors:Pena, P.V., Zhao, R., Kutateladze, T.G.
Deposit date:2006-02-24
Release date:2006-07-11
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2.
Nature, 442, 2006
2GP3
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF JMJD2A
Descriptor:Jumonji domain-containing protein 2A, ZINC ION, FE (II) ION
Authors:Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
Deposit date:2006-04-16
Release date:2006-05-23
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2GP5
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CRYSTAL STRUCTURE OF CATALYTIC CORE DOMAIN OF JMJD2A COMPLEXED WITH ALPHA-KETOGLUTARATE
Descriptor:Jumonji domain-containing protein 2A, ZINC ION, FE (II) ION, ...
Authors:Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
Deposit date:2006-04-16
Release date:2006-05-23
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2PNX
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THE PHD FINGER OF ING4 IN COMPLEX WITH AN H3K4ME3 HISTONE PEPTIDE
Descriptor:Inhibitor of growth protein 4, H3K4Me3 peptide, ZINC ION
Authors:Champagne, K.S., Johnson, K., Kutateladze, T.G.
Deposit date:2007-04-25
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
Mol.Cell, 33, 2009
2QIC
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CRYSTAL STRUCTURE OF THE ING1 PHD FINGER IN COMPLEX WITH A HISTONE H3K4ME3 PEPTIDE
Descriptor:Inhibitor of growth protein 1, H3K4ME3 PEPTIDE, ZINC ION
Authors:Pena, P.V., Champagne, K., Zhao, R., Kutateladze, T.G.
Deposit date:2007-07-03
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
J.Mol.Biol., 380, 2008
3C6W
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CRYSTAL STRUCTURE OF THE ING5 PHD FINGER IN COMPLEX WITH H3K4ME3 PEPTIDE
Descriptor:Inhibitor of growth protein 5, H3K4me3 histone peptide, ZINC ION
Authors:Champagne, K.S., Pena, P.V., Johnson, K., Kutateladze, T.G.
Deposit date:2008-02-05
Release date:2008-06-03
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.
Proteins, 72, 2008
3LGF
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CRYSTAL STRUCTURE OF THE 53BP1 TANDEM TUDOR DOMAIN IN COMPLEX WITH P53K370ME2
Descriptor:Tumor suppressor p53-binding protein 1, DIMETHYLATED p53 Lysine 370 PEPTIDE, TRIETHYLENE GLYCOL, ...
Authors:Roy, S., Kutateladze, T.G.
Deposit date:2010-01-20
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGL
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CRYSTAL STRUCTURE OF THE 53BP1 TANDEM TUDOR DOMAIN IN COMPLEX WITH P53K382ME2
Descriptor:Tumor suppressor p53-binding protein 1, DIMETHYLATED p53 LYSINE 382 PEPTIDE, TRIETHYLENE GLYCOL, ...
Authors:Roy, S., Kutateladze, T.G.
Deposit date:2010-01-20
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LH0
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CRYSTAL STRUCTURE OF THE 53BP1 TANDEM TUDOR DOMAIN IN COMPLEX WITH P53K372ME2
Descriptor:Tumor suppressor p53-binding protein 1, DIMETHYLATED p53 LYSINE 372 PEPTIDE, TRIETHYLENE GLYCOL, ...
Authors:Roy, S., Kutateladze, T.G.
Deposit date:2010-01-21
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3MDF
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CRYSTAL STRUCTURE OF THE RRM DOMAIN OF CYCLOPHILIN 33
Descriptor:Peptidyl-prolyl cis-trans isomerase E
Authors:Hom, R.A., Chang, P.Y., Roy, S., Mussleman, C.A., Glass, K.C., Seleznevia, A.I., Gozani, O., Ismagilov, R.F., Cleary, M.L., Kutateladze, T.G.
Deposit date:2010-03-30
Release date:2010-05-12
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.
J.Mol.Biol., 400, 2010
3RCP
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CRYSTAL STRUCTURE OF THE FAPP1 PLECKSTRIN HOMOLOGY DOMAIN
Descriptor:Pleckstrin homology domain-containing family A member 3, GLYCEROL
Authors:Roy, S., He, J., Kutateladze, T.G.
Deposit date:2011-03-31
Release date:2011-04-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain.
J.Biol.Chem., 286, 2011
4HCZ
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PHF1 TUDOR IN COMPLEX WITH H3K36ME3
Descriptor:PHD finger protein 1, H3L-like histone
Authors:Musselman, C.A., Roy, S., Nunez, J., Kutateladze, T.G.
Deposit date:2012-10-01
Release date:2012-11-14
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
4L58
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CRYSTAL STRUCTURE OF THE MLL5 PHD FINGER IN COMPLEX WITH H3K4ME3
Descriptor:Histone-lysine N-methyltransferase MLL5, Histone H3 peptide, ZINC ION
Authors:Tong, Q., Ali, M., Kutateladze, T.G.
Deposit date:2013-06-10
Release date:2013-06-26
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Molecular basis for chromatin binding and regulation of MLL5.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L7X
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CRYSTAL STRUCTURE OF THE DIDO PHD FINGER IN COMPLEX WITH H3K4ME3
Descriptor:Death-inducer obliterator 1, Histone H3 peptide, ZINC ION
Authors:Tong, Q., Gatchalian, J., Kutateladze, T.G.
Deposit date:2013-06-14
Release date:2013-07-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Dido3 PHD Modulates Cell Differentiation and Division.
Cell Rep, 4, 2013
4OUF
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CRYSTAL STRUCTURE OF CBP BROMODOMAIN
Descriptor:CREB-binding protein, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL
Authors:Roy, S., Das, C., Tyler, J.K., Kutateladze, T.G.
Deposit date:2014-02-17
Release date:2014-03-12
Last modified:2014-04-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
5D7E
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CRYSTAL STRUCTURE OF TAF14 YEATS DOMAIN IN COMPLEX WITH H3K9AC
Descriptor:Transcription initiation factor TFIID subunit 14, H3K9ac, DI(HYDROXYETHYL)ETHER, ...
Authors:Andrews, F.H., Shanle, E.K., Strahl, B.D., Kutateladze, T.G.
Deposit date:2015-08-13
Release date:2015-09-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.
Genes Dev., 29, 2015
5ERC
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X-RAY CRYSTAL STRUCTURE OF BRPF1 PZP DOMAIN
Descriptor:Peregrin, ZINC ION, CALCIUM ION
Authors:Klein, B.J., Andrews, F.H., Kutateladze, T.G.
Deposit date:2015-11-13
Release date:2015-12-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Nucleic Acids Res., 44, 2016
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