2TPR
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1MBC
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1TRB
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1J3D
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1J3C
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1J3X
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3KK9
| CaMKII Substrate Complex B | Descriptor: | Calcium/calmodulin dependent protein kinase II | Authors: | Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H. | Deposit date: | 2009-11-04 | Release date: | 2010-02-09 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (3.206 Å) | Cite: | Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat.Struct.Mol.Biol., 17, 2010
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3KK8
| CaMKII Substrate Complex A | Descriptor: | Calcium/calmodulin dependent protein kinase II, MAGNESIUM ION | Authors: | Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H. | Deposit date: | 2009-11-04 | Release date: | 2010-02-09 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat.Struct.Mol.Biol., 17, 2010
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3KL8
| CaMKIINtide Inhibitor Complex | Descriptor: | Calcium/calmodulin dependent protein kinase II, Calcium/calmodulin-dependent protein kinase II inhibitor 1 | Authors: | Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H. | Deposit date: | 2009-11-06 | Release date: | 2010-02-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.372 Å) | Cite: | Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat.Struct.Mol.Biol., 17, 2010
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1A06
| CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT | Descriptor: | CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE | Authors: | Kuriyan, J, Goldberg, J. | Deposit date: | 1997-12-09 | Release date: | 1998-04-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I. Cell(Cambridge,Mass.), 84, 1996
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2MA2
| Solution structure of RasGRP2 EF hands bound to calcium | Descriptor: | RAS guanyl-releasing protein 2 | Authors: | Kuriyan, J, Iwig, J, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J, Wemmer, D, Roose, J. | Deposit date: | 2013-06-24 | Release date: | 2013-08-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife, 2, 2013
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1BF5
| TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX | Descriptor: | DNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA | Authors: | Kuriyan, J, Zhao, Y, Chen, X, Vinkemeier, U, Jeruzalmi, D, Darnell Jr, J.E. | Deposit date: | 1998-05-27 | Release date: | 1998-08-12 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell(Cambridge,Mass.), 93, 1998
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7WJ3
| Crystal structure of HLA-C*1402 complexed with 4-mer lipopeptide | Descriptor: | 1,2-ETHANEDIOL, 4-mer lipopeptide, Beta-2-microglobulin, ... | Authors: | Kuroha, J, Morita, D, Asa, M, Sugita, M. | Deposit date: | 2022-01-05 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.56343615 Å) | Cite: | Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding. J.Biol.Chem., 298, 2022
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7WJ2
| Crystal structure of HLA-C*1402 complexed with 8-mer HIV gag peptide | Descriptor: | 1,2-ETHANEDIOL, 8-mer peptide, ACETATE ION, ... | Authors: | Kuroha, J, Morita, D, Asa, M, Sugita, M. | Deposit date: | 2022-01-05 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding. J.Biol.Chem., 298, 2022
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3HP4
| Crystal structure of psychrotrophic esterase EstA from Pseudoalteromonas sp. 643A inhibited by monoethylphosphonate | Descriptor: | GDSL-esterase | Authors: | Brzuszkiewicz, A, Nowak, E, Dauter, Z, Dauter, M, Cieslinski, H, Kur, J. | Deposit date: | 2009-06-03 | Release date: | 2009-06-30 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of EstA esterase from psychrotrophic Pseudoalteromonas sp. 643A covalently inhibited by monoethylphosphonate. Acta Crystallogr.,Sect.F, 65, 2009
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4GS3
| Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tencongensis solved ab initio | Descriptor: | Single-stranded DNA-binding protein | Authors: | Liebschner, D, Brzezinski, K, Dauter, M, Dauter, Z, Nowak, M, Kur, J, Olszewski, M. | Deposit date: | 2012-08-27 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tengcongensis solved ab initio. Acta Crystallogr.,Sect.D, 68, 2012
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2AXW
| Structure of DraD invasin from uropathogenic Escherichia coli | Descriptor: | CHLORIDE ION, DraD invasin, GLYCEROL | Authors: | Jedrzejczak, R, Dauter, Z, Dauter, M, Piatek, R, Zalewska, B, Mroz, M, Bury, K, Nowicki, B, Kur, J. | Deposit date: | 2005-09-06 | Release date: | 2005-11-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Structure of DraD invasin from uropathogenic Escherichia coli: a dimer with swapped beta-tails. Acta Crystallogr.,Sect.D, 62, 2006
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7SA7
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6W69
| The structure of F64, S172A Keap1-BTB domain | Descriptor: | Kelch-like ECH-associated protein 1 | Authors: | Mena, E.L, Gee, C.L, Kuriyan, J, Rape, M. | Deposit date: | 2020-03-16 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural basis for dimerization quality control. Nature, 586, 2020
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6W68
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3KEX
| Crystal structure of the catalytically inactive kinase domain of the human epidermal growth factor receptor 3 (HER3) | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Receptor tyrosine-protein kinase erbB-3 | Authors: | Jura, N, Shan, Y, Cao, X, Shaw, D.E, Kuriyan, J. | Deposit date: | 2009-10-26 | Release date: | 2009-12-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3. Proc.Natl.Acad.Sci.USA, 106, 2009
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4XZ0
| ZAP-70-tSH2:compound-A complex | Descriptor: | 1-(3-{5-[(3-chlorobenzyl)sulfonyl]-1H-tetrazol-1-yl}phenyl)ethanone, SULFATE ION, Tyrosine-protein kinase ZAP-70 | Authors: | Barros, T, Kuriyan, J, Visperas, P.R, Winger, J.A. | Deposit date: | 2015-02-03 | Release date: | 2015-06-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. Biochem. J., 465, 2015
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4XZ1
| ZAP-70-tSH2:Compound-B adduct | Descriptor: | 2-[(7-chloro-4-nitro-2,1,3-benzoxadiazol-5-yl)amino]ethanol, Tyrosine-protein kinase ZAP-70, doubly phosphorylated ITAM peptide | Authors: | Barros, T, Kuriyan, J, Winger, J.A, Visperas, P.R. | Deposit date: | 2015-02-03 | Release date: | 2015-07-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. Biochem. J., 465, 2015
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4XEY
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4XUF
| Crystal structure of the FLT3 kinase domain bound to the inhibitor quizartinib (AC220) | Descriptor: | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea, Receptor-type tyrosine-protein kinase FLT3 | Authors: | Zorn, J.A, Wang, Q, Fujimura, E, Barros, T, Kuriyan, J. | Deposit date: | 2015-01-25 | Release date: | 2015-04-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure of the FLT3 Kinase Domain Bound to the Inhibitor Quizartinib (AC220). Plos One, 10, 2015
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