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3SEC
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CRYSTAL STRUCTURE OF METHANOTHERMOBACTER THERMAUTOTROPHICUS OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH PYRAZOFURIN MONOPHOSPHATE
分子名称:Orotidine 5'-phosphate decarboxylase, GLYCEROL, (1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2011-06-10
公開日2012-04-25
最終更新日2012-05-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of methanococcus thermolithotrophicus orotidine 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
To be Published
1E3U
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MAD STRUCTURE OF OXA10 CLASS D BETA-LACTAMASE
分子名称:BETA-LACTAMASE OXA-10, GOLD (I) CYANIDE ION, SULFATE ION, ...
著者Maveyraud, L., Golemi, D., Kotra, L.P., Tranier, S., Vakulenko, S., Mobashery, S., Samama, J.P.
登録日2000-06-23
公開日2001-01-12
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Insights Into Class D Beta-Lactamases are Revealed by the Crystal Structure of the Oxa10 Enzyme from Pseudomonas Aeruginosa
Structure, 8, 2000
1E4D
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STRUCTURE OF OXA10 BETA-LACTAMASE AT PH 8.3
分子名称:BETA-LACTAMASE OXA-10, SULFATE ION, 1,2-ETHANEDIOL
著者Maveyraud, L., Golemi, D., Kotra, L.P., Tranier, S., Vakulenko, S., Mobashery, S., Samama, J.P.
登録日2000-07-03
公開日2001-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights Into Class D Beta-Lactamases are Revealed by the Crystal Structure of the Oxa10 Enzyme from Pseudomonas Aeruginosa
Structure, 8, 2000
1EWZ
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CRYSTAL STRUCTURE OF THE OXA-10 BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA
分子名称:BETA LACTAMASE OXA-10
著者Golemi, D., Maveyraud, L., Vakulenko, S., Tranier, S., Ishiwata, A., Kotra, L.P., Samama, J.P., Mobashery, S.
登録日2000-04-28
公開日2000-11-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The First Structural and Mechanistic Insights for Class D beta-Lactamases: Evidence for a Novel Catalytic Process for Turnover of beta-Lactam Antibiotics
J.Am.Chem.Soc., 122, 2000
1X1Z
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OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE (ODCASE) COMPLEXED WITH BMP (PRODUCED FROM 6-CYANOUMP)
分子名称:Orotidine 5'-phosphate decarboxylase, 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL
著者Fujihashi, M., Bello, A.M., Poduch, E., Wei, L., Annedi, S.C., Pai, E.F., Kotra, L.P.
登録日2005-04-15
公開日2005-12-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献An unprecedented twist to ODCase catalytic activity
J.Am.Chem.Soc., 127, 2005
2E6Y
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COVALENT COMPLEX OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE (ODCASE) WITH 6-IODO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE, GLYCEROL
著者Fujihashi, M., Bello, A.M., Kotra, L.P., Pai, E.F.
登録日2007-01-05
公開日2007-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Potent, Covalent Inhibitor of Orotidine 5'-Monophosphate Decarboxylase with Antimalarial Activity.
J.Med.Chem., 50, 2007
2Q8Z
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM OROTIDINE 5'-PHOSPHATE DECARBOXYLASE COMPLEXED WITH 6-AMINO-UMP
分子名称:Orotidine-monophosphate-decarboxylase, SULFATE ION, 6-AMINOURIDINE 5'-MONOPHOSPHATE, ...
著者Liu, Y., Lau, W., Bello, A.M., Kotra, L.P., Hui, R., Pai, E.F.
登録日2007-06-12
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase.
J.Med.Chem., 51, 2008
2QAF
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM OROTIDINE 5'-PHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 6-IODO-UMP
分子名称:Orotidine 5' monophosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE, SULFATE ION
著者Liu, Y., Lau, W., Bello, A.M., Kotra, L.P., Hui, R., Pai, E.F.
登録日2007-06-15
公開日2008-04-29
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase
J.Med.Chem., 51, 2008
3BAR
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM OROTIDINE 5'-PHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 6-AZIDO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE
著者Liu, Y., Bello, A.M., Poduch, E., Lau, W., Kotra, L.P., Pai, E.F.
登録日2007-11-08
公開日2008-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase.
J.Med.Chem., 51, 2008
3BGG
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH BMP
分子名称:Uridine 5'-monophosphate synthase, 6-HYDROXYURIDINE-5'-PHOSPHATE
著者Liu, Y., Tang, H.L., Wang, X.Y., Kotra, L.P., Pai, E.F.
登録日2007-11-26
公開日2007-12-11
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of Human Orotidine 5'-monophosphate Decarboxylase complexed with BMP
To be Published
3BGJ
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 6-IODO-UMP
分子名称:Uridine 5'-monophosphate synthase, URIDINE-5'-MONOPHOSPHATE, GLYCEROL
著者Liu, Y., Tang, H.L., Bello, A.M., Devalla, S., Kotra, L.P., Pai, E.F.
登録日2007-11-26
公開日2008-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP
To be Published
3BK0
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-CN-UMP
分子名称:Uridine 5'-monophosphate synthase, SULFATE ION, 5-CYANO-URIDINE-5'-MONOPHOSPHATE, ...
著者Liu, Y., Tang, H.L., Avina, M.E.M., Kotra, L.P., Pai, E.F.
登録日2007-12-05
公開日2008-11-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with 5-CN-UMP
To be Published
3DBP
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 6-NH2-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, SULFATE ION, 6-AMINOURIDINE 5'-MONOPHOSPHATE
著者Liu, Y., To, T., Bello, A.M., Kotra, L.P., Pai, E.F.
登録日2008-06-02
公開日2009-06-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP
To be Published
3G3M
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 5-FLUORO-6-IODO-UMP
分子名称:Uridine 5'-monophosphate synthase, 5-FLUORO-URIDINE-5'-MONOPHOSPHATE
著者Liu, Y., Tang, H.L., Bello, A.M., Poduch, E., Kotra, L.P., Pai, E.F.
登録日2009-02-02
公開日2009-03-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
J.Med.Chem., 52, 2009
3MI2
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH PYRAZOFURIN MONOPHOSPHATE
分子名称:Uridine 5'-monophosphate synthase, (1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol
著者Liu, Y., To, T., Kotra, L.P., Pai, E.F.
登録日2010-04-09
公開日2010-05-26
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase.
Bioorg.Med.Chem., 18, 2010
3MO7
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 2'-FLUORO-6-IODO-UMP
分子名称:Uridine 5'-monophosphate synthase, 2'-deoxy-2'-fluorouridine 5'-(dihydrogen phosphate), GLYCEROL
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2010-04-22
公開日2011-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Novel interactions of fluorinated nucleotide derivatives targeting orotidine 5'-monophosphate decarboxylase.
J.Med.Chem., 54, 2011
3MW7
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CRYSTAL STRUCTURE OF HUMAN OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-FLUORO-UMP(PRODUCED FROM 5-FLUORO-6-AMINO-UMP)
分子名称:Uridine 5'-monophosphate synthase, 5-FLUORO-URIDINE-5'-MONOPHOSPHATE
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2010-05-05
公開日2011-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-UMP(produced from 5-fluoro-6-amino-UMP)
To be Published
3MWA
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 2-PRIME-FLUORO-6-IODO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, 2'-deoxy-2'-fluorouridine 5'-(dihydrogen phosphate), DI(HYDROXYETHYL)ETHER, ...
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2010-05-05
公開日2011-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase covalently modified by 2-prime-fluoro-6-iodo-UMP
To be Published
3N2M
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-FLUORO-6-AMINO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2010-05-18
公開日2011-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP
To be Published
3N34
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-FLUORO-6-AMINO-UMP, PRODUCED FROM 5-FLUORO-6-AZIDO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), TRIETHYLENE GLYCOL, ...
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2010-05-19
公開日2011-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP
To be Published
3N3M
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 6-AMINO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, TRIETHYLENE GLYCOL, 1,2-ETHANEDIOL, ...
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2010-05-20
公開日2011-04-06
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 6-amino-UMP
To be Published
3S9Y
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CRYSTAL STRUCTURE OF P. FALCIPARUM OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-FLUORO-6-AMINO-UMP IN SPACE GROUP P21, PRODUCED FROM 5-FLUORO-6-AZIDO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), SULFATE ION, ...
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2011-06-02
公開日2012-04-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
J.Med.Chem., 52, 2009
3SGU
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CRYSTAL STRUCTURE OF METHANOTHERMOBACTER THERMAUTOTROPHICUS OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 5-FLUORO-6-IODO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, 5-FLUORO-URIDINE-5'-MONOPHOSPHATE
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2011-06-15
公開日2012-05-02
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase covalently modified by 5-fluoro-6-iodo-UMP
To be Published
3SSJ
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CRYSTAL STRUCTURE OF METHANOTHERMOBACTER THERMAUTOTROPHICUS OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 5-FLUORO-6-AMINO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), GLYCEROL
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2011-07-08
公開日2012-05-02
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP
To be Published
3SW6
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CRYSTAL STRUCTURE OF METHANOTHERMOBACTER THERMAUTOTROPHICUS OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE COVALENTLY MODIFIED BY 5-FLUORO-6-AZIDO-UMP
分子名称:Orotidine 5'-phosphate decarboxylase, 5-FLUORO-URIDINE-5'-MONOPHOSPHATE
著者Liu, Y., Kotra, L.P., Pai, E.F.
登録日2011-07-13
公開日2012-05-02
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase covalently modified by 5-fluoro-6-azido-UMP
To be Published
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