4XZR
 
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8EOE
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8EOF
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8EOS
 | | M. tuberculosis RNAP elongation complex with NusG and CMPCPP | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (36-MER), DNA (38-MER), ... | | Authors: | Vishwakarma, R.K, Murakami, K.S. | | Deposit date: | 2022-10-04 | | Release date: | 2023-02-01 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EXY
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8EHQ
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8EJ3
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8EOT
 | | M. tuberculosis RNAP elongation complex with NusG | | Descriptor: | DNA (31-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Vishwakarma, R.K, Murakami, K.S. | | Deposit date: | 2022-10-04 | | Release date: | 2023-02-01 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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5JJ3
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5JJ1
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4PVZ
 | | Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 | | Descriptor: | Importin subunit alpha, Inner nuclear membrane protein HEH2 | | Authors: | Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C. | | Deposit date: | 2014-03-18 | | Release date: | 2015-08-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
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7UXE
 | | Pseudomonas phage E217 small terminase (TerS) | | Descriptor: | Small terminase | | Authors: | Lokareddy, R.K, Hou, C.-F.D, Doll, S.G, Li, F, Gillilan, R, Forti, F, Briani, F, Cingolani, G. | | Deposit date: | 2022-05-05 | | Release date: | 2022-09-28 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Terminase Subunits from the Pseudomonas-Phage E217.
J.Mol.Biol., 434, 2022
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3GZ2
 | | Crystal structure of IpgC in complex with an IpaB peptide | | Descriptor: | Chaperone protein ipgC, GLYCEROL, IMIDAZOLE, ... | | Authors: | Lokareddy, R.K, Lunelli, M, Kolbe, M. | | Deposit date: | 2009-04-06 | | Release date: | 2010-04-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Combination of two separate binding domains defines stoichiometry between type III secretion system chaperone IpgC and translocator protein IpaB
J.Biol.Chem., 285, 2010
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4HRF
 | | Atomic structure of DUSP26 | | Descriptor: | Dual specificity protein phosphatase 26 | | Authors: | Lokareddy, R.K, Bhardwaj, A, Cingolani, G. | | Deposit date: | 2012-10-27 | | Release date: | 2013-01-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.
Biochemistry, 52, 2013
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4YI0
 | | Structure of mouse importin a1 bound to Pom121NLS | | Descriptor: | Importin subunit alpha-1, Nuclear envelope pore membrane protein POM 121 | | Authors: | Lokareddy, R.K, Cingolani, G. | | Deposit date: | 2015-02-27 | | Release date: | 2016-01-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.806 Å) | | Cite: | Mammalian Pom121 and yeast Heh2 share IBB-like NLSs that support targeting to the inner nuclear membrane
To Be Published
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6KH9
 | | Solution structure of bovine insulin amyloid intermediate-1 | | Descriptor: | Insulin A chain, Insulin B chain | | Authors: | Ratha, B.N, Kar, R.K, Brender, J.B, Bhunia, A. | | Deposit date: | 2019-07-14 | | Release date: | 2020-08-12 | | Last modified: | 2020-11-18 | | Method: | SOLUTION NMR | | Cite: | High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
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6KH8
 | | Solution structure of Zn free Bovine Pancreatic Insulin in 20% acetic acid-d4 (pH 1.9) | | Descriptor: | Insulin A Chain, Insulin B chain | | Authors: | Bhunia, A, Ratha, B.N, Kar, R.K, Brender, J.R. | | Deposit date: | 2019-07-14 | | Release date: | 2020-10-07 | | Last modified: | 2020-11-18 | | Method: | SOLUTION NMR | | Cite: | High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
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6KHA
 | | Solution structure of bovine insulin amyloid intermediate-2 | | Descriptor: | Insulin A chain, Insulin B chain | | Authors: | Ratha, B.N, Kar, R.K, Brender, J.B, Bhunia, A. | | Deposit date: | 2019-07-14 | | Release date: | 2020-08-12 | | Last modified: | 2020-11-18 | | Method: | SOLUTION NMR | | Cite: | High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
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6K59
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2M2C
 | | Solution structure of Duplex DNA | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*TP*AP*GP*CP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*AP*TP*GP*CP*TP*AP*CP*GP*CP*G)-3') | | Authors: | Ghosh, A, Kar, R.K, Chatterjee, S, Bhunia, A. | | Deposit date: | 2012-12-18 | | Release date: | 2013-01-23 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Indolicidin targets duplex DNA: structural and mechanistic insight through a combination of spectroscopy and microscopy.
Chemmedchem, 9, 2014
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4MBB
 | | Cubic crystal form of PIR1 dual specificity phosphatase core | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | | Authors: | Sankhala, R.S, Lokareddy, R.K, Cingolani, G. | | Deposit date: | 2013-08-19 | | Release date: | 2013-12-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.849 Å) | | Cite: | Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
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5T94
 | | Crystal structure of Kap60 bound to yeast RCC1 (Prp20) | | Descriptor: | Guanine nucleotide exchange factor SRM1, Importin subunit alpha | | Authors: | Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G. | | Deposit date: | 2016-09-09 | | Release date: | 2017-09-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.631 Å) | | Cite: | Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
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5V5O
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5V5P
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5TBK
 | | Crystal structure of human importin a3 bound to RCC1 | | Descriptor: | Importin subunit alpha-3, Regulator of chromosome condensation | | Authors: | Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G. | | Deposit date: | 2016-09-12 | | Release date: | 2017-09-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
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