8EOS
M. tuberculosis RNAP elongation complex with NusG and CMPCPP
Summary for 8EOS
| Entry DOI | 10.2210/pdb8eos/pdb |
| EMDB information | 28466 |
| Descriptor | DNA-directed RNA polymerase subunit alpha, MAGNESIUM ION, ZINC ION, ... (11 entities in total) |
| Functional Keywords | transcription elongation rna polymerase pausing nusg cryo-em, transcription |
| Biological source | Mycobacterium tuberculosis H37Rv More |
| Total number of polymer chains | 9 |
| Total formula weight | 421508.37 |
| Authors | Vishwakarma, R.K.,Murakami, K.S. (deposition date: 2022-10-04, release date: 2023-02-01, Last modification date: 2024-06-19) |
| Primary citation | Vishwakarma, R.K.,Qayyum, M.Z.,Babitzke, P.,Murakami, K.S. Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase. Proc.Natl.Acad.Sci.USA, 120:e2218516120-e2218516120, 2023 Cited by PubMed: 36745813DOI: 10.1073/pnas.2218516120 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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