8EOS
M. tuberculosis RNAP elongation complex with NusG and CMPCPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA-directed RNA polymerase subunit alpha | polymer | 347 | 37745.3 | 2 | UniProt (P9WGZ1) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB | Mycobacterium tuberculosis H37Rv | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C | DNA-directed RNA polymerase subunit beta | polymer | 1178 | 130018.8 | 1 | UniProt (P9WGY9) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB | Mycobacterium tuberculosis H37Rv | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D | DNA-directed RNA polymerase subunit beta' | polymer | 1316 | 146969.0 | 1 | UniProt (P9WGY7) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Mycobacterium tuberculosis H37Rv | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E | DNA-directed RNA polymerase subunit omega | polymer | 110 | 11851.1 | 1 | UniProt (P9WGY5) Pfam (PF01192) In PDB | Mycobacterium tuberculosis H37Rv | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | G | Transcription termination/antitermination protein NusG | polymer | 238 | 25471.5 | 1 | UniProt (P9WIU9) Pfam (PF02357) In PDB | Mycobacterium tuberculosis H37Rv | |
| 6 | T | DNA (38-MER) | polymer | 40 | 12211.8 | 1 | synthetic construct | ||
| 7 | N | DNA (36-MER) | polymer | 40 | 12324.9 | 1 | synthetic construct | ||
| 8 | R | RNA (5'-R(P*AP*AP*GP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3') | polymer | 20 | 6510.0 | 1 | synthetic construct | ||
| 9 | C | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine | non-polymer | 481.2 | 1 | Chemie (2TM) | |||
| 10 | D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 11 | D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 420847.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 660.6 | |
| All* | Total formula weight | 421508.4 |
