8EOT
M. tuberculosis RNAP elongation complex with NusG
Summary for 8EOT
Entry DOI | 10.2210/pdb8eot/pdb |
EMDB information | 28467 |
Descriptor | DNA-directed RNA polymerase subunit alpha, ZINC ION, DNA-directed RNA polymerase subunit beta', ... (10 entities in total) |
Functional Keywords | transcription elongation rna polymerase pausing nusg cryo-em, transcription |
Biological source | Mycobacterium tuberculosis H37Rv More |
Total number of polymer chains | 9 |
Total formula weight | 421002.88 |
Authors | Vishwakarma, R.K.,Murakami, K.S. (deposition date: 2022-10-04, release date: 2023-02-01, Last modification date: 2024-06-19) |
Primary citation | Vishwakarma, R.K.,Qayyum, M.Z.,Babitzke, P.,Murakami, K.S. Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase. Proc.Natl.Acad.Sci.USA, 120:e2218516120-e2218516120, 2023 Cited by PubMed: 36745813DOI: 10.1073/pnas.2218516120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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