8EOT

M. tuberculosis RNAP elongation complex with NusG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DNA-directed RNA polymerase subunit alpha	polymer	347	37745.3	2	UniProt (P9WGZ1) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB	Mycobacterium tuberculosis H37Rv	RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2	D	DNA-directed RNA polymerase subunit beta'	polymer	1316	146969.0	1	UniProt (P9WGY7) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB	Mycobacterium tuberculosis H37Rv	RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
3	E	DNA-directed RNA polymerase subunit omega	polymer	110	11851.1	1	UniProt (P9WGY5) Pfam (PF01192) In PDB	Mycobacterium tuberculosis H37Rv	RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
4	T	DNA (33-MER)	polymer	40	12211.8	1		synthetic construct
5	N	DNA (31-MER)	polymer	40	12324.9	1		synthetic construct
6	R	RNA (5'-R(P*AP*AP*GP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3')	polymer	20	6510.0	1		synthetic construct
7	G	Transcription termination/antitermination protein NusG	polymer	238	25471.5	1	UniProt (P9WIU9) Pfam (PF02357) In PDB	Mycobacterium tuberculosis H37Rv
8	C	DNA-directed RNA polymerase subunit beta	polymer	1178	130018.8	1	UniProt (P9WGY9) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB	Mycobacterium tuberculosis H37Rv	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
9	D	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
10	D	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	420847.8
Non-Polymers*	Number of molecules	3
	Total formula weight	155.1
All*	Total formula weight	421002.9

*Water molecules are not included.