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4RV0
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CRYSTAL STRUCTURE OF TN COMPLEX
Descriptor:Transitional endoplasmic reticulum ATPase TER94, Nuclear protein localization protein 4 homolog, SULFATE ION
Authors:Hao, Q., Jiao, S., Shi, Z.B., Zhou, Z.C.
Deposit date:2014-11-23
Release date:2015-11-25
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Crystal structure of TN complex
To be Published
4LN0
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CRYSTAL STRUCTURE OF THE VGLL4-TEAD4 COMPLEX
Descriptor:Transcriptional enhancer factor TEF-3, Transcription cofactor vestigial-like protein 4, DI(HYDROXYETHYL)ETHER, ...
Authors:Wang, H., Shi, Z., Zhou, Z.
Deposit date:2013-07-11
Release date:2014-02-26
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer.
Cancer Cell, 25, 2014
4FI9
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STRUCTURE OF HUMAN SUN-KASH COMPLEX
Descriptor:SUN domain-containing protein 2, Nesprin-2
Authors:Wang, W.J., Shi, Z.B.
Deposit date:2012-06-08
Release date:2012-07-18
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into SUN-KASH complexes across the nuclear envelope.
Cell Res., 22, 2012
4FZA
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CRYSTAL STRUCTURE OF MST4-MO25 COMPLEX
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase MST4, GLYCEROL
Authors:Shi, Z.B., Zhou, Z.C.
Deposit date:2012-07-06
Release date:2013-03-06
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism
Structure, 21, 2013
4FZD
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CRYSTAL STRUCTURE OF MST4-MO25 COMPLEX WITH WSF MOTIF
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase MST4, C-terminal peptide from Serine/threonine-protein kinase MST4, ...
Authors:Shi, Z.B., Zhou, Z.C.
Deposit date:2012-07-06
Release date:2013-03-06
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism
Structure, 21, 2013
4FZF
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CRYSTAL STRUCTURE OF MST4-MO25 COMPLEX WITH DKI
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase MST4, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE
Authors:Shi, Z.B., Zhou, Z.C.
Deposit date:2012-07-06
Release date:2013-03-06
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism
Structure, 21, 2013
4GEH
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CRYSTAL STRUCTURE OF MST4 DIMERIZATION DOMAIN COMPLEX WITH PDCD10
Descriptor:Programmed cell death protein 10, Serine/threonine-protein kinase MST4
Authors:Zhang, M., Shi, Z.B., Zhou, Z.C.
Deposit date:2012-08-02
Release date:2013-04-17
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural mechanism of CCM3 heterodimerization with GCKIII kinases
Structure, 21, 2013
4N6J
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CRYSTAL STRUCTURE OF HUMAN STRIATIN-3 COILED COIL DOMAIN
Descriptor:Striatin-3
Authors:Chen, C.C., Shi, Z.B., Zhou, Z.C.
Deposit date:2013-10-13
Release date:2014-02-26
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Striatins Contain a Noncanonical Coiled Coil That Binds PP2A A to Form a 2:2 Heterotetrameric Core of Striatin-interacting Phosphatase and Kinase (STRIPAK) Complex
J.Biol.Chem., 2014
4NZW
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CRYSTAL STRUCTURE OF STK25-MO25 COMPLEX
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase 25, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE
Authors:Feng, M., Hao, Q., Zhou, Z.C.
Deposit date:2013-12-13
Release date:2014-12-03
Method:X-RAY DIFFRACTION (3.583 Å)
Cite:Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
J.Struct.Biol., 186, 2014
4O27
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CRYSTAL STRUCTURE OF MST3-MO25 COMPLEX WITH WIF MOTIF
Descriptor:Calcium-binding protein 39, Serine/threonine-protein kinase 24, 5-mer peptide from serine/threonine-protein kinase 24, ...
Authors:Hao, Q., Feng, M., Zhou, Z.C.
Deposit date:2013-12-16
Release date:2014-12-03
Method:X-RAY DIFFRACTION (3.185 Å)
Cite:Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
J.Struct.Biol., 186, 2014
4Z8M
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CRYSTAL STRUCTURE OF THE MAVS-TRAF6 COMPLEX
Descriptor:TNF receptor-associated factor 6, Peptide from Mitochondrial antiviral-signaling protein
Authors:Shi, Z.B., Zhou, Z.
Deposit date:2015-04-09
Release date:2015-09-23
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Insights into Mitochondrial Antiviral Signaling Protein (MAVS)-Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Signaling
J.Biol.Chem., 290, 2015
5GZB
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CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR TEAD4 IN COMPLEX WITH M-CAT DNA
Descriptor:Transcriptional enhancer factor TEF-3, DNA (5'-D(*TP*TP*GP*CP*AP*TP*TP*CP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*GP*AP*AP*TP*GP*CP*AP*A)-3'), ...
Authors:He, F., Shi, Z.B., Zhou, Z.C.
Deposit date:2016-09-28
Release date:2017-04-19
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:DNA-binding mechanism of the Hippo pathway transcription factor TEAD4
Oncogene, 36, 2017
5YF4
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A KINASE COMPLEX MST4-MOB4
Descriptor:MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION
Authors:Chen, M., Zhou, Z.C.
Deposit date:2017-09-20
Release date:2018-08-15
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.
J. Biol. Chem., 293, 2018
6AKK
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CRYSTAL STRUCTURE OF THE SECOND COILED-COIL DOMAIN OF SIKE1
Descriptor:Suppressor of IKBKE 1, GLYCEROL
Authors:Zhou, L., Chen, M., Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
6AKL
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CRYSTAL STRUCTURE OF STRIATIN3 IN COMPLEX WITH SIKE1 COILED-COIL DOMAIN
Descriptor:Suppressor of IKBKE 1, Striatin-3
Authors:Zhou, L., Chen, M., Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
6AKM
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CRYSTAL STRUCTURE OF SLMAP-SIKE1 COMPLEX
Descriptor:Suppressor of IKBKE 1, Sarcolemmal membrane-associated protein, GLYCEROL
Authors:Ma, J., Chen, M., Zhou, Z.C.
Deposit date:2018-09-02
Release date:2019-01-16
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019