4GEH

Crystal structure of MST4 dimerization domain complex with PDCD10

Summary for 4GEH

DescriptorProgrammed cell death protein 10, Serine/threonine-protein kinase MST4 (3 entities in total)
Functional Keywordsalpha helix-rich protein, serine/threonine-protein kinase, protein binding, cell proliferation, cell growth, protein binding-transferase complex, protein binding/transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q9BUL8 Q9P289
Total number of polymer chains4
Total molecular weight67930.2
Authors
Zhang, M.,Shi, Z.B.,Zhou, Z.C. (deposition date: 2012-08-02, release date: 2013-04-17, Last modification date: 2013-07-17)
Primary citation
Zhang, M.,Dong, L.,Shi, Z.,Jiao, S.,Zhang, Z.,Zhang, W.,Liu, G.,Chen, C.,Feng, M.,Hao, Q.,Wang, W.,Yin, M.,Zhao, Y.,Zhang, L.,Zhou, Z.
Structural mechanism of CCM3 heterodimerization with GCKIII kinases
Structure, 21:680-688, 2013
PubMed: 23541896 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2013.02.015
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26330.2%2.0%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 4geh
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Molmil generated image of 4geh
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Molmil generated image of 4geh
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4geh.pdb1.gz [45.95 KB])
Coordinate files for Biological unit (4geh.pdb2.gz [45.65 KB])