4GEH

Crystal structure of MST4 dimerization domain complex with PDCD10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Programmed cell death protein 10	polymer	207	23953.6	2	UniProt (Q9BUL8) Pfam (PF20929) Pfam (PF06840)	Homo sapiens (human)	Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15
2	B, D (B, D)	Serine/threonine-protein kinase MST4	polymer	91	10011.5	2	UniProt (Q9P289) Pfam (PF20929)	Homo sapiens (human)	Mammalian STE20-like protein kinase 4, MST-4, Mst3 and SOK1-related kinase, STE20-like kinase MST4, Serine/threonine-protein kinase MASK
3	E, F, G, H (A, B, C, D)	water	water		18.0	174	Chemie (HOH)

Sequence modifications

A, C: 9 - 212 (UniProt: Q9BUL8)

PDB	External Database	Details
Gly 6	-	expression tag
Met 7	-	expression tag
Ala 8	-	expression tag

B, D: 325 - 413 (UniProt: Q9P289)

PDB	External Database	Details
Met 323	-	expression tag
Gly 324	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	67930.2
All*	Total formula weight	67930.2

*Water molecules are not included.