4LN0

Crystal structure of the VGLL4-TEAD4 complex

Summary for 4LN0

Entry DOI	10.2210/pdb4ln0/pdb
Descriptor	Transcriptional enhancer factor TEF-3, Transcription cofactor vestigial-like protein 4, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywords	tea/atts domain family, vestigial/tondu family, transcription factor, transcription cofactor, development, transcription
Biological source	Mus musculus (mouse) More
Cellular location	Nucleus: Q62296 Nucleus (By similarity): Q80V24
Total number of polymer chains	3
Total formula weight	58678.17
Authors	Wang, H.,Shi, Z.,Zhou, Z. (deposition date: 2013-07-11, release date: 2014-02-26, Last modification date: 2023-11-08)
Primary citation	Jiao, S.,Wang, H.,Shi, Z.,Dong, A.,Zhang, W.,Song, X.,He, F.,Wang, Y.,Zhang, Z.,Wang, W.,Wang, X.,Guo, T.,Li, P.,Zhao, Y.,Ji, H.,Zhang, L.,Zhou, Z. A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer. Cancer Cell, 25:166-180, 2014 Cited by PubMed: 24525233 DOI: 10.1016/j.ccr.2014.01.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.896 Å)

Structure validation