Author results

1E6U
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE
Descriptor:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
Authors:Rosano, C., Izzo, G., Bolognesi, M.
Deposit date:2000-08-23
Release date:2000-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
1E7Q
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE S107A
Descriptor:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
Authors:Rosano, C., Izzo, G., Bolognesi, M.
Deposit date:2000-09-07
Release date:2000-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
1E7R
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE Y136E
Descriptor:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
Authors:Rosano, C., Izzo, G., Bolognesi, M.
Deposit date:2000-09-07
Release date:2000-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
1E7S
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE K140R
Descriptor:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
Authors:Rosano, C., Zuccotti, S., Izzo, G., Bolognesi, M.
Deposit date:2000-09-07
Release date:2000-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
2BMC
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AURORA-2 T287D T288D COMPLEXED WITH PHA-680632
Descriptor:SERINE THREONINE-PROTEIN KINASE 6, (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE
Authors:Cameron, A.D., Izzo, G., Sagliano, A., Rusconi, L., Storici, P., Fancelli, D., Berta, D., Bindi, S., Catana, C., Forte, B., Giordano, P., Mantegani, S., Meroni, M., Moll, J., Pittala, V., Severino, D., Tonani, R., Varasi, M., Vulpetti, A., Vianello, P.
Deposit date:2005-03-11
Release date:2005-03-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition.
J.Med.Chem., 48, 2005
2J4Z
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STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-680626
Descriptor:SERINE THREONINE-PROTEIN KINASE 6, 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ARSENIC
Authors:Cameron, A.D., Izzo, G., Storici, P., Rusconi, L., Fancelli, D., Varasi, M., Berta, D., Bindi, S., Forte, B., Severino, D., Tonani, R., Vianello, P.
Deposit date:2006-09-08
Release date:2006-11-06
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
J. Med. Chem., 49, 2006
2J50
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STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-739358
Descriptor:SERINE/THREONINE-PROTEIN KINASE 6, N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, SULFATE ION
Authors:Cameron, A.D., Izzo, G., Storici, P., Rusconi, L., Fancelli, D., Varasi, M., Berta, D., Bindi, S., Forte, B., Severino, D., Tonani, R., Vianello, P.
Deposit date:2006-09-08
Release date:2006-11-06
Last modified:2015-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile.
J.Med.Chem., 49, 2006
1P82
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NMR STRUCTURE OF 1-25 FRAGMENT OF MYCOBACTERIUM TUBERCULOSIS CPN10
Descriptor:10 kDa chaperonin
Authors:Ciutti, A., Spiga, O., Giannozzi, E., Scarselli, M., Di Maro, D., Calamandrei, D., Niccolai, N., Bernini, A.
Deposit date:2003-05-06
Release date:2003-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of 1-25 fragment of Cpn10 from Mycobacterium Tuberculosis
To be Published
1P83
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NMR STRUCTURE OF 1-25 FRAGMENT OF MYCOBACTERIUM TUBERCULOSIS CPN10
Descriptor:10 kDa chaperonin
Authors:Ciutti, A., Spiga, O., Giannozzi, E., Scarselli, M., Di Maro, D., Calamandrei, D., Niccolai, N., Bernini, A.
Deposit date:2003-05-06
Release date:2003-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of 1-25 fragment of Cpn10 from Mycobacterium Tuberculosis
To be Published
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