3P0F

Structure of hUPP2 in an inactive conformation with bound 5-benzylacyclouridine

Summary for 3P0F

Entry DOI	10.2210/pdb3p0f/pdb
Related	3P0E
Descriptor	Uridine phosphorylase 2, 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, COBALT (II) ION, ... (5 entities in total)
Functional Keywords	uridine phosphorylase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	33651.07
Authors	Roosild, T.P.,Castronovo, S.,Villoso, A. (deposition date: 2010-09-28, release date: 2011-09-07, Last modification date: 2023-09-06)
Primary citation	Roosild, T.P.,Castronovo, S.,Villoso, A.,Ziemba, A.,Pizzorno, G. A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity. J.Struct.Biol., 176:229-237, 2011 Cited by PubMed: 21855639 DOI: 10.1016/j.jsb.2011.08.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation