Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3EUE

Crystal structure of ligand-free human uridine phosphorylase 1 (hUPP1)

Summary for 3EUE
Entry DOI10.2210/pdb3eue/pdb
Related3EUF
DescriptorUridine phosphorylase 1, MAGNESIUM ION, SULFATE ION, ... (4 entities in total)
Functional Keywordsnucleoside phosphorylase, uridine rescue, alternative splicing, glycosyltransferase, transferase
Biological sourceHomo sapiens
Total number of polymer chains1
Total formula weight36170.99
Authors
Roosild, T.P. (deposition date: 2008-10-09, release date: 2009-03-31, Last modification date: 2023-09-06)
Primary citationRoosild, T.P.,Castronovo, S.,Fabbiani, M.,Pizzorno, G.
Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy.
Bmc Struct.Biol., 9:14-14, 2009
Cited by
PubMed: 19291308
DOI: 10.1186/1472-6807-9-14
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

218500

PDB entries from 2024-04-17

PDB statisticsPDBj update infoContact PDBjnumon