3EUF

Crystal structure of BAU-bound human uridine phosphorylase 1

Summary for 3EUF

Entry DOI	10.2210/pdb3euf/pdb
Related	3EUE
Descriptor	Uridine phosphorylase 1, 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	nucleoside phosphorylase, uridine rescue, 5-benzylacyclouridine, alternative splicing, glycosyltransferase, transferase
Biological source	Homo sapiens
Total number of polymer chains	4
Total formula weight	145687.50
Authors	Roosild, T.P. (deposition date: 2008-10-10, release date: 2009-03-31, Last modification date: 2023-09-06)
Primary citation	Roosild, T.P.,Castronovo, S.,Fabbiani, M.,Pizzorno, G. Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy. Bmc Struct.Biol., 9:14-14, 2009 Cited by PubMed: 19291308 DOI: 10.1186/1472-6807-9-14 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation