Author results

1CH8
  • Download 1ch8
  • View 1ch8
Molmil generated image of 1ch8
STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH A STRINGENT EFFECTOR, PPG2':3'P
分子名称:PROTEIN (ADENYLOSUCCINATE SYNTHETASE), NITRATE ION, MAGNESIUM ION, ...
著者Hou, Z., Cashel, M., Fromm, H.J., Honzatko, R.B.
登録日1999-03-31
公開日1999-12-29
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.
J.Biol.Chem., 274, 1999
1CIB
  • Download 1cib
  • View 1cib
Molmil generated image of 1cib
STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH GDP, IMP, HADACIDIN, AND NO3
分子名称:ADENYLOSUCCINATE SYNTHETASE, NITRATE ION, MAGNESIUM ION, ...
著者Hou, Z., Cashel, M., Fromm, H.J., Honzatko, R.B.
登録日1999-03-31
公開日2000-04-05
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.
J.Biol.Chem., 274, 1999
1KJX
  • Download 1kjx
  • View 1kjx
Molmil generated image of 1kjx
IMP COMPLEX OF E. COLI ADENYLOSUCCINATE SYNTHETASE
分子名称:Adenylosuccinate Synthetase, INOSINIC ACID
著者Hou, Z., Wang, W., Fromm, H.J., Honzatko, R.B.
登録日2001-12-05
公開日2002-03-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
1KKB
  • Download 1kkb
  • View 1kkb
Molmil generated image of 1kkb
COMPLEX OF ESCHERICHIA COLI ADENYLOSUCCINATE SYNTHETASE WITH IMP AND HADACIDIN
分子名称:Adenylosuccinate Synthetase, HADACIDIN, INOSINIC ACID
著者Hou, Z., Wang, W., Fromm, H.J., Honzatko, R.B.
登録日2001-12-06
公開日2002-03-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
1KKF
  • Download 1kkf
  • View 1kkf
Molmil generated image of 1kkf
COMPLEX OF E. COLI ADENYLOSUCCINATE SYNTHETASE WITH IMP, HADACIDIN, PYROPHOSPHATE, AND MG
分子名称:Adenylosuccinate Synthetase, MAGNESIUM ION, DIPHOSPHATE, ...
著者Hou, Z., Wang, W., Fromm, H.J., Honzatko, R.B.
登録日2001-12-07
公開日2002-03-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
1Z1A
  • Download 1z1a
  • View 1z1a
Molmil generated image of 1z1a
S. CEREVISIAE SIR1 ORC-INTERACTION DOMAIN
分子名称:Regulatory protein SIR1
著者Hou, Z., Bernstein, D.A., Fox, C.A., Keck, J.L.
登録日2005-03-03
公開日2005-06-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZHI
  • Download 1zhi
  • View 1zhi
Molmil generated image of 1zhi
COMPLEX OF THE S. CEREVISIAE ORC1 AND SIR1 INTERACTING DOMAINS
分子名称:Origin recognition complex subunit 1, Regulatory protein SIR1
著者Hou, Z., Bernstein, D.A., Fox, C.A., Keck, J.L.
登録日2005-04-25
公開日2005-06-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3VAY
  • Download 3vay
  • View 3vay
Molmil generated image of 3vay
CRYSTAL STRUCTURE OF 2-HALOACID DEHALOGENASE FROM PSEUDOMONAS SYRINGAE PV. TOMATO DC3000
分子名称:HAD-superfamily hydrolase, MAGNESIUM ION, IODIDE ION
著者Hou, Z., Zhang, H., Li, M., Chang, W.
登録日2011-12-30
公開日2013-01-02
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.979 Å)
主引用文献Structure of 2-haloacid dehalogenase from Pseudomonas syringae pv. tomato DC3000
Acta Crystallogr.,Sect.D, 69, 2013
5VJI
  • Download 5vji
  • View 5vji
Molmil generated image of 5vji
CRYSTAL STRUCTURE OF THE CLOCK TRANSCRIPTION DOMAIN EXON19 IN COMPLEX WITH A REPRESSOR
分子名称:Circadian locomoter output cycles protein kaput, CLOCK-interacting pacemaker
著者Hou, Z., Su, L., Pei, J., Grishin, N.V., Zhang, H.
登録日2017-04-19
公開日2017-06-07
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
5VJX
  • Download 5vjx
  • View 5vjx
Molmil generated image of 5vjx
CRYSTAL STRUCTURE OF THE CLOCK TRANSCRIPTION DOMAIN EXON19 IN COMPLEX WITH A REPRESSOR
分子名称:CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput
著者Hou, Z., Su, L., Pei, J., Grishin, N.V., Zhang, H.
登録日2017-04-20
公開日2017-12-06
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
2FL7
  • Download 2fl7
  • View 2fl7
Molmil generated image of 2fl7
S. CEREVISIAE SIR3 BAH DOMAIN
分子名称:Regulatory protein SIR3
著者Keck, J.L., Hou, Z., Daner, J.R., Fox, C.A.
登録日2006-01-05
公開日2006-05-09
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 A resolution.
Protein Sci., 15, 2006
1HON
  • Download 1hon
  • View 1hon
Molmil generated image of 1hon
STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREE CELSIUS
分子名称:ADENYLOSUCCINATE SYNTHETASE, AMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Poland, B.W., Hou, Z., Bruns, C., Fromm, H.J., Honzatko, R.B.
登録日1996-04-26
公開日1996-11-08
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli.
J.Biol.Chem., 271, 1996
1HOO
  • Download 1hoo
  • View 1hoo
Molmil generated image of 1hoo
STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI AT PH 6.5 AND 25 DEGREES CELSIUS
分子名称:ADENYLOSUCCINATE SYNTHETASE, AMINOPHOSPHONIC ACID-GUANYLATE ESTER, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Poland, B.W., Hou, Z., Bruns, C., Fromm, H.J., Honzatko, R.B.
登録日1996-04-26
公開日1997-02-12
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli.
J.Biol.Chem., 271, 1996
1HOP
  • Download 1hop
  • View 1hop
Molmil generated image of 1hop
STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREES CELSIUS
分子名称:ADENYLOSUCCINATE SYNTHETASE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Poland, B.W., Hou, Z., Bruns, C., Fromm, H.J., Honzatko, R.B.
登録日1996-04-26
公開日1996-11-08
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli.
J.Biol.Chem., 271, 1996
3AXW
  • Download 3axw
  • View 3axw
Molmil generated image of 3axw
CRYSTAL STRUCTURE OF HUMAN CK2ALPHA COMPLEXED WITH A POTENT INHIBITOR
分子名称:Casein kinase II subunit alpha, 4-(5-amino-1,3,4-thiadiazol-2-yl)benzoic acid
著者Kinoshita, T., Nakanishi, I.
登録日2011-04-18
公開日2012-04-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Design of Novel Potent Protein Kinase CK2 (CK2) Inhibitors with Phenyl-azole Scaffolds
J.Med.Chem., 55, 2012
1MD2
  • Download 1md2
  • View 1md2
Molmil generated image of 1md2
CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013
分子名称:CHOLERA TOXIN B SUBUNIT, [5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLCARBAMOYL)-PENTYL]-CARBAMIC ACID METHYL ESTER, 3-ETHYLAMINO-4-METHYLAMINO-CYCLOBUTANE-1,2-DIONE, ...
著者Zhang, Z., Merritt, E.A., Ahn, M., Roach, C., Hol, W.G.J., Fan, E.
登録日2002-08-06
公開日2002-12-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin.
J.Am.Chem.Soc., 124, 2002
4QLI
  • Download 4qli
  • View 4qli
Molmil generated image of 4qli
A NOVEL PHOSPHO-SWITCH IN THE LINKER REGION OF THE SNAIL ZINC FINGER PROTEIN WHICH REGULATES 14-3-3 ASSOCIATION, DNA BINDING AND EPITHELIAL-MESENCHYMAL DIFFERENTIATION
分子名称:14-3-3 protein sigma, Zinc finger protein SNAI1, MAGNESIUM ION, ...
著者Bier, D., Ottmann, C.
登録日2014-06-12
公開日2015-06-17
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
To be Published
4ZYT
  • Download 4zyt
  • View 4zyt
Molmil generated image of 4zyt
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND N-{4-[4-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)BENZYL]BENZOYL}-L-GLUTAMIC ACID (AGF23)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, N-{4-[4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]benzoyl}-L-glutamic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZYU
  • Download 4zyu
  • View 4zyu
Molmil generated image of 4zyu
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND N-{4-[4-(2-AMINO-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDIN-6-YL)-BUTYL]BENZOYL}-L-GLUTAMIC ACID (AGF50)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, N-{4-[4-(2-amino-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]benzoyl}-L-glutamic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZYV
  • Download 4zyv
  • View 4zyv
Molmil generated image of 4zyv
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND N-({5-[(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)BUTYL]THIOPHEN-2-YL}CARBONYL)-L-GLUTAMIC ACID (AGF71)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, N-({5-[4-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophen-2-yl}carbonyl)-L-glutamic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.053 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZYW
  • Download 4zyw
  • View 4zyw
Molmil generated image of 4zyw
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND N-({5-[(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)PROPYL]THIOPHEN-2-YL}CARBONYL)-L-GLUTAMIC ACID (AGF94)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, N-({5-[3-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophen-2-yl}carbonyl)-L-glutamic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZYX
  • Download 4zyx
  • View 4zyx
Molmil generated image of 4zyx
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({4-[4-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]-PYRIMIDIN-6-YL)BUTYL]THIOPHENE-2-CARBONYL}AMINO)PENTANEDIOIC ACID (AGF117)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, N-({4-[4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophen-2-yl}carbonyl)-L-glutamic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZYY
  • Download 4zyy
  • View 4zyy
Molmil generated image of 4zyy
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({5-[4-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]-PYRIMIDIN-6-YL)BUTYL]THIOPHENE-3-CARBONYL}AMINO)PENTANEDIOIC ACID (AGF118)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, (S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)butyl]thiophene-3-carbonyl}amino)pentanedioic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZYZ
  • Download 4zyz
  • View 4zyz
Molmil generated image of 4zyz
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-(7-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)HEPTANAMIDO)PENTANEDIOIC ACID (AGF145)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, (S)-2-(7-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)heptanamido)pentanedioic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
4ZZ0
  • Download 4zz0
  • View 4zz0
Molmil generated image of 4zz0
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-(8-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)OCTANAMIDO)PENTANEDIOIC ACID (AGF147)
分子名称:Trifunctional purine biosynthetic protein adenosine-3, GLYCINAMIDE RIBONUCLEOTIDE, (S)-2-(8-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)octanamido)pentanedioic acid
著者Deis, S.M., Dann III, C.E.
登録日2015-05-22
公開日2016-04-20
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.
Biochemistry, 55, 2016
<12>