1CH8

STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH A STRINGENT EFFECTOR, PPG2':3'P

Summary for 1CH8

Entry DOI	10.2210/pdb1ch8/pdb
Descriptor	PROTEIN (ADENYLOSUCCINATE SYNTHETASE), NITRATE ION, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	ligase, adenylosuccinate synthetase, gtp-hydrolysing enzymes, purine 2 nucleotide biosynthesis, ppgpp, ppg2':3'p, stringent effector
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0A7D4
Total number of polymer chains	1
Total formula weight	48328.35
Authors	Hou, Z.,Cashel, M.,Fromm, H.J.,Honzatko, R.B. (deposition date: 1999-03-31, release date: 1999-12-29, Last modification date: 2023-08-09)
Primary citation	Hou, Z.,Cashel, M.,Fromm, H.J.,Honzatko, R.B. Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase. J.Biol.Chem., 274:17505-17510, 1999 Cited by PubMed: 10364182 DOI: 10.1074/jbc.274.25.17505 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation