6VVI
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6VVH
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7MDS
| Crystal structure of AtDHDPS1 in complex with MBDTA-2 | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ... | Authors: | Hall, C.J, Soares da Costa, T.P, Panjikar, S. | Deposit date: | 2021-04-06 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants. Elife, 10, 2021
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6P90
| Crystal structure of PaDHDPS2-H56Q mutant | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, GLYCEROL | Authors: | Impey, R.E, Panjikar, S, Hall, C.J, Bock, L.J, Sutton, J.M, Perugini, M.A, Soares da Costa, T.P. | Deposit date: | 2019-06-08 | Release date: | 2019-08-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation. Febs J., 287, 2020
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2KH2
| Solution structure of a scFv-IL-1B complex | Descriptor: | Interleukin-1 beta, scFv | Authors: | Wilkinson, I.C, Hall, C.J, Veverka, V, Muskett, F.W, Stephens, P.E, Taylor, R.J, Henry, A.J, Carr, M.D. | Deposit date: | 2009-03-23 | Release date: | 2009-09-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development. J.Biol.Chem., 284, 2009
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7UJB
| N-terminal domain deletion variant of Eta | Descriptor: | DEAD/DEAH box RNA helicase | Authors: | Qayyum, M.Z, Murakami, K.S. | Deposit date: | 2022-03-30 | Release date: | 2022-08-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.12 Å) | Cite: | The structure and activities of the archaeal transcription termination factor Eta detail vulnerabilities of the transcription elongation complex. Proc.Natl.Acad.Sci.USA, 119, 2022
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1UWH
| The complex of wild type B-RAF and BAY439006. | Descriptor: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, CHLORIDE ION | Authors: | Barford, D, Roe, S.M, Wan, P.T.C, Cancer Genome Project | Deposit date: | 2004-02-05 | Release date: | 2004-03-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf Cell(Cambridge,Mass.), 116, 2004
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1UWJ
| The complex of mutant V599E B-RAF and BAY439006. | Descriptor: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE | Authors: | Barford, D, Roe, S.M, Wan, P.T.C, Cancer Genome Project | Deposit date: | 2004-02-05 | Release date: | 2004-03-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf Cell(Cambridge,Mass.), 116, 2004
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1EAG
| Secreted aspartic proteinase (SAP2) from Candida albicans complexed with A70450 | Descriptor: | ASPARTIC PROTEINASE (SAP2 GENE PRODUCT), N-ethyl-N-[(4-methylpiperazin-1-yl)carbonyl]-D-phenylalanyl-N-[(1S,2S,4R)-4-(butylcarbamoyl)-1-(cyclohexylmethyl)-2-hydroxy-5-methylhexyl]-L-norleucinamide | Authors: | Cutfield, J.F, Cutfield, S.M. | Deposit date: | 1996-05-31 | Release date: | 1996-12-23 | Last modified: | 2012-01-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of a major secreted aspartic proteinase from Candida albicans in complexes with two inhibitors. Structure, 3, 1995
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2WMN
| Structure of the complex between DOCK9 and Cdc42-GDP. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GUANOSINE-5'-DIPHOSPHATE | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-07-02 | Release date: | 2009-09-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.391 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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2WM9
| Structure of the complex between DOCK9 and Cdc42. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GLYCEROL | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-06-30 | Release date: | 2009-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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2WMO
| Structure of the complex between DOCK9 and Cdc42. | Descriptor: | CELL DIVISION CONTROL PROTEIN 42 HOMOLOG, DEDICATOR OF CYTOKINESIS PROTEIN 9, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yang, J, Roe, S.M, Barford, D. | Deposit date: | 2009-07-02 | Release date: | 2009-09-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activation of Rho Gtpases by Dock Exchange Factors is Mediated by a Nucleotide Sensor. Science, 325, 2009
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1ZAP
| SECRETED ASPARTIC PROTEASE FROM C. ALBICANS | Descriptor: | N-ethyl-N-[(4-methylpiperazin-1-yl)carbonyl]-D-phenylalanyl-N-[(1S,2S,4R)-4-(butylcarbamoyl)-1-(cyclohexylmethyl)-2-hydroxy-5-methylhexyl]-L-norleucinamide, SECRETED ASPARTIC PROTEINASE, ZINC ION | Authors: | Abad-Zapatero, C, Muchmore, S.W. | Deposit date: | 1996-01-16 | Release date: | 1997-04-21 | Last modified: | 2012-01-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a secreted aspartic protease from C. albicans complexed with a potent inhibitor: implications for the design of antifungal agents. Protein Sci., 5, 1996
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