5HWI
| Crystal structure of selenomethionine labelled gama glutamyl cyclotransferease specific to glutathione from yeast | Descriptor: | GLYCEROL, Glutathione-specific gamma-glutamylcyclotransferase, SUCCINIC ACID | Authors: | Kaur, A, Gautam, R, Srivastava, R, Chandel, A, Kumar, A, Karthikeyan, S, Bachhawat, A.K. | Deposit date: | 2016-01-29 | Release date: | 2016-12-14 | Last modified: | 2017-01-25 | Method: | X-RAY DIFFRACTION (1.755 Å) | Cite: | ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione J. Biol. Chem., 292, 2017
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5HWK
| Crystal structure of gama glutamyl cyclotransferease specific to glutathione from yeast | Descriptor: | BENZOIC ACID, Glutathione-specific gamma-glutamylcyclotransferase, PHOSPHATE ION | Authors: | Kaur, A, Gautam, R, Srivastava, R, Chandel, A, Kumar, A, Karthikeyan, S, Bachhawat, A.K. | Deposit date: | 2016-01-29 | Release date: | 2016-12-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.344 Å) | Cite: | ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione J. Biol. Chem., 292, 2017
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4I14
| Crystal Structure of Mtb-ribA2 (Rv1415) | Descriptor: | Riboflavin biosynthesis protein RibBA, SULFATE ION, ZINC ION | Authors: | Singh, M, Kumar, P, Yadav, S, Gautam, R, Sharma, N, Karthikeyan, S. | Deposit date: | 2012-11-20 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis Acta Crystallogr.,Sect.D, 69, 2013
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3LS6
| Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate synthase in complex with sulfate and zinc | Descriptor: | 3,4-Dihydroxy-2-butanone 4-phosphate synthase, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kumar, P, Karthikeyan, S. | Deposit date: | 2010-02-12 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Potential anti-bacterial drug target: structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2. Proteins, 78, 2010
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3LQU
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3LRJ
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6ORO
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ... | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2019-04-30 | Release date: | 2019-06-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
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6ORQ
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ... | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2019-04-30 | Release date: | 2019-06-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
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6ORN
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 | Descriptor: | 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2019-04-30 | Release date: | 2019-06-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
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6ORP
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ... | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2019-04-30 | Release date: | 2019-06-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
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7RYV
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7RYU
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7KDE
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7TFN
| Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ... | Authors: | Yang, Z, Bjorkman, P.J. | Deposit date: | 2022-01-06 | Release date: | 2022-01-19 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
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7TFO
| Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ... | Authors: | Yang, Z, Bjorkman, P.J. | Deposit date: | 2022-01-06 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13, 2022
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7MXE
| Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ... | Authors: | Abernathy, M.E, Bjorkman, P.J. | Deposit date: | 2021-05-19 | Release date: | 2021-10-27 | Last modified: | 2021-11-03 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope. Npj Vaccines, 6, 2021
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