Author results

1A1R
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HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX
分子名称:NS3 PROTEIN, NS4A PROTEIN, ZINC ION
著者Kim, J.L., Morgenstern, K.A., Lin, C., Fox, T., Dwyer, M.D., Landro, J.A., Chambers, S.P., Markland, W., Lepre, C.A., O'Malley, E.T., Harbeson, S.L., Rice, C.M., Murcko, M.A., Caron, P.R., Thomson, J.A.
登録日1997-12-15
公開日1998-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide.
Cell(Cambridge,Mass.), 87, 1996
1CM8
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PHOSPHORYLATED MAP KINASE P38-GAMMA
分子名称:PHOSPHORYLATED MAP KINASE P38-GAMMA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Bellon, S., Fitzgibbon, M.J., Fox, T., Hsiao, H.M., Wilson, K.P.
登録日1999-05-17
公開日2000-05-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation.
Structure Fold.Des., 7, 1999
2AHT
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SOLUTION STRUCTURE OF DOMAIN 6 FROM THE AI5(GAMMA)GROUP II INTRON
分子名称:27-MER
著者Erat, M.C., Zerbe, O., Fox, T., Sigel, R.K.O.
登録日2005-07-28
公開日2006-10-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of domain 6 from a self-splicing group II intron ribozyme: a Mg(2+) binding site is located close to the stacked branch adenosine.
Chembiochem, 8, 2007
2L61
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PROTEIN AND METAL CLUSTER STRUCTURE OF THE WHEAT METALLOTHIONEIN DOMAIN G-EC-1. THE SECOND PART OF THE PUZZLE.
分子名称:EC protein I/II, CADMIUM ION
著者Loebus, J., Peroza, E.A., Bluethgen, N., Fox, T., Meyer-Klaucke, W., Zerbe, O., Freisinger, E.
登録日2010-11-12
公開日2011-05-25
最終更新日2013-06-19
実験手法SOLUTION NMR
主引用文献Protein and metal cluster structure of the wheat metallothionein domain gamma-E(c)-1: the second part of the puzzle.
J.Biol.Inorg.Chem., 16, 2011
2L62
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PROTEIN AND METAL CLUSTER STRUCTURE OF THE WHEAT METALLOTHIONEIN DOMAIN G-EC-1. THE SECOND PART OF THE PUZZLE.
分子名称:EC protein I/II, ZINC ION
著者Loebus, J., Peroza, E.A., Bluethgen, N., Fox, T., Meyer-Klaucke, W., Zerbe, O., Freisinger, E.
登録日2010-11-12
公開日2011-05-25
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Protein and metal cluster structure of the wheat metallothionein domain gamma-E(c)-1: the second part of the puzzle.
J.Biol.Inorg.Chem., 16, 2011
6B44
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND TARGET DSDNA
分子名称:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
最終更新日2017-12-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B45
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX
分子名称:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B46
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF1
分子名称:CRISPR-associated protein Csy3, Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B47
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF2
分子名称:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B48
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CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF10
分子名称:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6EBK
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THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS
分子名称:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
登録日2018-08-06
公開日2018-08-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBL
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THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS, CYTOSOLIC DOMAIN
分子名称:Voltage-gated potassium channel subunit beta-2, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
登録日2018-08-06
公開日2018-08-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6EBM
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THE VOLTAGE-ACTIVATED KV1.2-2.1 PADDLE CHIMERA CHANNEL IN LIPID NANODISCS, TRANSMEMBRANE DOMAIN OF SUBUNIT ALPHA
分子名称:Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera
著者Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.
登録日2018-08-06
公開日2018-08-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
6N7V
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STRUCTURE OF BACTERIOPHAGE T7 GP4 (HELICASE-PRIMASE, E343Q MUTANT) IN COMPLEX WITH SSDNA, DTTP, AC DINUCLEOTIDE, AND CTP (FROM MULTIPLE LEAD COMPLEXES)
分子名称:DNA primase/helicase, DNA (93-MER), THYMIDINE-5'-TRIPHOSPHATE, ...
著者Gao, Y., Fox, T., Val, N., Yang, W.
登録日2018-11-28
公開日2019-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6N7W
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STRUCTURE OF BACTERIOPHAGE T7 LEADING-STRAND DNA POLYMERASE (D5A/E7A)/TRX IN COMPLEX WITH A DNA FORK AND INCOMING DTTP (FROM MULTIPLE LEAD COMPLEXES)
分子名称:DNA-directed DNA polymerase, TrxA, DNA (25-MER), ...
著者Gao, Y., Fox, T., Val, N., Yang, W.
登録日2018-11-28
公開日2019-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6N9U
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STRUCTURE OF BACTERIOPHAGE T7 LAGGING-STRAND DNA POLYMERASE (D5A/E7A) INTERACTING WITH PRIMASE DOMAINS OF TWO GP4 SUBUNITS BOUND TO AN RNA/DNA HYBRID AND DTTP (FROM LAGS1)
分子名称:DNA primase/helicase, DNA-directed DNA polymerase, RNA (5'-R(*AP*CP*CP*AP*G)-D(P*(DOC))-3'), ...
著者Gao, Y., Fox, T., Val, N., Yang, W.
登録日2018-12-04
公開日2019-03-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6N9V
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STRUCTURE OF BACTERIOPHAGE T7 LAGGING-STRAND DNA POLYMERASE (D5A/E7A) AND GP4 (HELICASE/PRIMASE) BOUND TO DNA INCLUDING RNA/DNA HYBRID, AND AN INCOMING DTTP (LAGS1)
分子名称:DNA primase/helicase, DNA-directed DNA polymerase, Primer, ...
著者Gao, Y., Fox, T., Val, N., Yang, W.
登録日2018-12-04
公開日2019-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6N9X
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STRUCTURE OF BACTERIOPHAGE T7 LAGGING-STRAND DNA POLYMERASE (D5A/E7A) AND GP4 (HELICASE/PRIMASE) BOUND TO DNA INCLUDING RNA/DNA HYBRID, AND AN INCOMING DTTP (LAGS3)
分子名称:DNA primase/helicase, DNA-directed DNA polymerase, Primer, ...
著者Gao, Y., Fox, T., Val, N., Yang, W.
登録日2018-12-04
公開日2019-03-06
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
1PME
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STRUCTURE OF PENTA MUTANT HUMAN ERK2 MAP KINASE COMPLEXED WITH A SPECIFIC INHIBITOR OF HUMAN P38 MAP KINASE
分子名称:ERK2, SULFATE ION, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
著者Xie, X.
登録日1998-06-08
公開日1999-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase.
Protein Sci., 7, 1998
1BT7
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THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES
分子名称:NS3 SERINE PROTEASE, ZINC ION
著者Barbato, G., Cicero, D.O., Nardi, M.C., Steinkuhler, C., Cortese, R., De Francesco, R., Bazzo, R.
登録日1998-09-01
公開日1999-06-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism.
J.Mol.Biol., 289, 1999
1F1J
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CRYSTAL STRUCTURE OF CASPASE-7 IN COMPLEX WITH ACETYL-ASP-GLU-VAL-ASP-CHO
分子名称:CASPASE-7 PROTEASE, ACE-ASP-GLU-VAL-ASP-CHO, SULFATE ION
著者Wei, Y., Charifson, P.S.
登録日2000-05-19
公開日2001-05-23
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity.
Chem.Biol., 7, 2000
1JNK
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THE C-JUN N-TERMINAL KINASE (JNK3S) COMPLEXED WITH MGAMP-PNP
分子名称:C-JUN N-TERMINAL KINASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Xie, X., Su, M.S.-S.
登録日1998-06-03
公開日1999-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.
Structure, 6, 1998
6ANV
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF1
分子名称:anti-CRISPR protein AcrF1 fused with C-terminal MBP tag, MALTOTETRAOSE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Yang, H., Patel, D.J.
登録日2017-08-14
公開日2017-10-25
実験手法X-RAY DIFFRACTION (2.265 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6ANW
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CRYSTAL STRUCTURE OF ANTI-CRISPR PROTEIN ACRF10
分子名称:anti-CRISPR protein AcrF10
著者Yang, H., Patel, D.J.
登録日2017-08-14
公開日2017-10-25
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6HMA
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IMPROVED MODEL DERIVED FROM CRYO-EM MAP OF STAPHYLOCOCCUS AUREUS LARGE RIBOSOMAL SUBUNIT
分子名称:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
著者Eyal, Z., Cimicata, G., Matzov, D., Fox, T., de Val, N., Zimmerman, E., Bashan, A., Yonath, A.
登録日2018-09-12
公開日2018-11-14
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit
To Be Published
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