6N9U

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)

Summary for 6N9U

• Entry DOI: 10.2210/pdb6n9u/pdb
• Related: 6N7I 6N7N 6N7S 6N7T 6N7V 6N7W 6N9V 6N9W 6N9X
• EMDB information: 0379 0380 0381 0382
• Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, RNA (5'-R(*AP*CP*CP*AP*G)-D(P*(DOC))-3'), ... (7 entities in total)
• Functional Keywords: dna polymerase, primase, helicase, dna replication, replisome, hydrolase, transferase-dna complex, transferase/dna
• Biological source: Enterobacteria phage T7; More
• Total number of polymer chains: 5
• Total formula weight: 221115.45

Authors

Gao, Y.,Fox, T.,Val, N.,Yang, W. (deposition date: 2018-12-04, release date: 2019-03-06, Last modification date: 2019-12-18)

• Primary citation: Gao, Y.,Cui, Y.,Fox, T.,Lin, S.,Wang, H.,de Val, N.,Zhou, Z.H.,Yang, W.; Structures and operating principles of the replisome.; Science, 363:-, 2019; PubMed: 30679383; DOI: 10.1126/science.aav7003

Experimental method

ELECTRON MICROSCOPY (3.7 Å)