3LBF | | CRYSTAL STRUCTURE OF PROTEIN L-ISOASPARTYL METHYLTRANSFERASE FROM ESCHERICHIA COLI | | Descriptor: | Protein-L-isoaspartate O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, PHOSPHATE ION, ... | | Authors: | Fang, P., Li, X., Wang, J., Niu, L., Teng, M. | | Deposit date: | 2010-01-08 | | Release date: | 2010-09-08 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the protein L-isoaspartyl methyltransferase from Escherichia coli
Cell Biochem.Biophys., 58, 2010
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3MNM | | CRYSTAL STRUCTURE OF GAE DOMAIN OF GGA2P FROM SACCHAROMYCES CEREVISIAE | | Descriptor: | ADP-ribosylation factor-binding protein GGA2, SULFATE ION, GLYCEROL | | Authors: | Fang, P., Wang, J., Li, X., Niu, L., Teng, M. | | Deposit date: | 2010-04-21 | | Release date: | 2010-09-08 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Structural basis for the specificity of the GAE domain of yGGA2 for its accessory proteins Ent3 and Ent5
Biochemistry, 49, 2010
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4P3N | | STRUCTURAL BASIS FOR FULL-SPECTRUM INHIBITION OF THREONYL-TRNA SYNTHETASE BY BORRELIDIN 1 | | Descriptor: | Threonine--tRNA ligase, cytoplasmic, (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, ... | | Authors: | Fang, P., Yu, X., Chen, K., Chen, X., Guo, M. | | Deposit date: | 2014-03-09 | | Release date: | 2015-03-11 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015
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4P3O | | STRUCTURAL BASIS FOR FULL-SPECTRUM INHIBITION OF THREONYL-TRNA SYNTHETASE BY BORRELIDIN 2 | | Descriptor: | Threonine--tRNA ligase, ZINC ION, (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, ... | | Authors: | Fang, P., Yu, X., Chen, K., Chen, X., Guo, M. | | Deposit date: | 2014-03-09 | | Release date: | 2015-03-11 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.505 Å) | | Cite: | Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015
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4P3P | | STRUCTURAL BASIS FOR FULL-SPECTRUM INHIBITION OF THREONYL-TRNA SYNTHETASE BY BORRELIDIN 3 | | Descriptor: | Threonine--tRNA ligase, ZINC ION, (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, ... | | Authors: | Fang, P., Yu, X., Chen, K., Chen, X., Guo, M. | | Deposit date: | 2014-03-09 | | Release date: | 2015-03-11 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015
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4YCU | | CRYSTAL STRUCTURE OF CLADOSPORIN IN COMPLEX WITH HUMAN LYSYL-TRNA SYNTHETASE | | Descriptor: | Lysine--tRNA ligase, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, cladosporin, ... | | Authors: | Fang, P., Wang, J., Guo, M. | | Deposit date: | 2015-02-20 | | Release date: | 2015-06-10 | | Last modified: | 2018-10-10 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor.
Chem. Biol., 22, 2015
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4YCV | |
4YCW | | CRYSTAL STRUCTURE OF CLADOSPORIN IN COMPLEX WITH PLASMODIUM LIKE HUMAN LYSYL-TRNA SYNTHETASE MUTANT | | Descriptor: | Lysine--tRNA ligase, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, ... | | Authors: | Fang, P., Wang, J., Guo, M. | | Deposit date: | 2015-02-20 | | Release date: | 2015-06-10 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Basis for Specific Inhibition of tRNA Synthetase by ATP Competitive Inhibitor
Chem.Biol., 22, 2015
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4DPG | | CRYSTAL STRUCTURE OF HUMAN LYSRS: P38/AIMP2 COMPLEX I | | Descriptor: | Lysine--tRNA ligase, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, ... | | Authors: | Fang, P., Wang, J., Bennett, S.P., Guo, M. | | Deposit date: | 2012-02-13 | | Release date: | 2013-02-13 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.844 Å) | | Cite: | Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription.
Mol.Cell, 49, 2013
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4TTV | | CRYSTAL STRUCTURE OF HUMAN THRRS COMPLEXING WITH A BIOENGINEERED MACROLIDE BC194 | | Descriptor: | Threonine--tRNA ligase, cytoplasmic, (1R,2R)-2-[(2S,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadec-6-en-2-yl]cyclobutanecarboxylic acid, ... | | Authors: | Fang, P., Guo, M. | | Deposit date: | 2014-06-23 | | Release date: | 2015-09-30 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor.
Sci Rep, 5, 2015
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5YZX | | CRYSTAL STRUCTURE OF E.COLI LYSU T146D MUTANT | | Descriptor: | Lysine--tRNA ligase, heat inducible, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, ... | | Authors: | Fang, P., Guo, M. | | Deposit date: | 2017-12-16 | | Release date: | 2018-12-19 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | A proposed role for MSC to reserve the canonical function in high eukaryotes prior to stimuli
To Be Published
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4EQE | |
4EQG | |
4EQH | |
2EXU | | CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE TRANSCRIPTION ELONGATION FACTORS SPT4-SPT5NGN DOMAIN | | Descriptor: | Transcription initiation protein SPT4/SPT5, ZINC ION, ETHANOL, ... | | Authors: | Xu, F., Guo, M., Fang, P., Teng, M., Niu, L. | | Deposit date: | 2005-11-08 | | Release date: | 2006-11-08 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Crystal Structure of Saccharomyces cerevisiae transcription elongation factors Spt4-Spt5NGN domain
To be published
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2JZY | |
3N9T | | CRYATAL STRUCTURE OF HYDROXYQUINOL 1,2-DIOXYGENASE FROM PSEUDOMONAS PUTIDA DLL-E4 | | Descriptor: | PnpC, 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, CITRATE ANION, ... | | Authors: | Liu, W., Shen, W., Fang, P., Li, J., Cui, Z. | | Deposit date: | 2010-05-31 | | Release date: | 2010-08-04 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4
To be Published
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3ONJ | |
3ONK | | YEAST ENT3_ENTH DOMAIN | | Descriptor: | Epsin-3 | | Authors: | Wang, J., Fang, P., Niu, L., Teng, M. | | Deposit date: | 2010-08-29 | | Release date: | 2011-07-20 | | Last modified: | 2011-12-21 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
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3ONL | | YEAST ENT3_ENTH-VTI1P_HABC COMPLEX STRUCTURE | | Descriptor: | Epsin-3, t-SNARE VTI1 | | Authors: | Wang, J., Fang, P., Niu, L., Teng, M. | | Deposit date: | 2010-08-29 | | Release date: | 2011-07-20 | | Last modified: | 2014-04-02 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Epsin N-terminal homology domains bind on opposite sides of two SNAREs
Proc.Natl.Acad.Sci.USA, 108, 2011
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4DKT | | CRYSTAL STRUCTURE OF HUMAN PEPTIDYLARGININE DEIMINASE 4 IN COMPLEX WITH N-ACETYL-L-THREONYL-L-ALPHA-ASPARTYL-N5-[(1E)-2-FLUOROETHANIMIDOYL]-L-ORNITHINAMIDE | | Descriptor: | Protein-arginine deiminase type-4, Thr-Asp-F-amidine, CALCIUM ION, ... | | Authors: | Jones, J.E., Slack, J.L., Fang, P., Zhang, X., Subramanian, V., Causey, C.P., Coonrod, S.A., Guo, M., Thompson, P.R. | | Deposit date: | 2012-02-04 | | Release date: | 2012-02-29 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Synthesis and Screening of a Haloacetamidine Containing Library To Identify PAD4 Selective Inhibitors.
Acs Chem.Biol., 7, 2012
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4N20 | | CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (0 MM CA2+) | | Descriptor: | Protein-arginine deiminase type-2, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | | Authors: | Slade, D.J., Zhang, X., Fang, P., Dreyton, C.J., Zhang, Y., Gross, M.L., Guo, M., Coonrod, S.A., Thompson, P.R. | | Deposit date: | 2013-10-04 | | Release date: | 2015-02-04 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.657 Å) | | Cite: | Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
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4N22 | | CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (50 UM CA2+) | | Descriptor: | Protein-arginine deiminase type-2, ACETATE ION, GLYCEROL, ... | | Authors: | Slade, D.J., Zhang, X., Fang, P., Dreyton, C.J., Zhang, Y., Gross, M.L., Guo, M., Coonrod, S.A., Thompson, P.R. | | Deposit date: | 2013-10-04 | | Release date: | 2015-02-04 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.889 Å) | | Cite: | Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
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4N24 | | CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (100 UM CA2+) | | Descriptor: | Protein-arginine deiminase type-2, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | | Authors: | Slade, D.J., Zhang, X., Fang, P., Dreyton, C.J., Zhang, Y., Gross, M.L., Guo, M., Coonrod, S.A., Thompson, P.R. | | Deposit date: | 2013-10-04 | | Release date: | 2015-02-04 | | Last modified: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (1.968 Å) | | Cite: | Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
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4N25 | | CRYSTAL STRUCTURE OF PROTEIN ARGININE DEIMINASE 2 (250 UM CA2+) | | Descriptor: | Protein-arginine deiminase type-2, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | | Authors: | Slade, D.J., Zhang, X., Fang, P., Dreyton, C.J., Zhang, Y., Gross, M.L., Guo, M., Coonrod, S.A., Thompson, P.R. | | Deposit date: | 2013-10-04 | | Release date: | 2015-02-04 | | Last modified: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (1.931 Å) | | Cite: | Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.
Acs Chem.Biol., 10, 2015
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