4DPG
Crystal Structure of Human LysRS: P38/AIMP2 Complex I
Summary for 4DPG
Entry DOI | 10.2210/pdb4dpg/pdb |
Related | 4DPJ |
Descriptor | Lysine--tRNA ligase, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, ... (7 entities in total) |
Functional Keywords | lysyl-trna synthetase, lysrs, p38, aimp2, multi trna synthetase complex sub-complex, ligase-apoptosis complex, ligase/apoptosis |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform Cytoplasmic: Cytoplasm, cytosol . Isoform Mitochondrial: Mitochondrion : Q15046 Cytoplasm, cytosol : Q13155 |
Total number of polymer chains | 12 |
Total formula weight | 503812.56 |
Authors | Fang, P.,Wang, J.,Bennett, S.P.,Guo, M. (deposition date: 2012-02-13, release date: 2013-02-13, Last modification date: 2024-02-28) |
Primary citation | Ofir-Birin, Y.,Fang, P.,Bennett, S.P.,Zhang, H.M.,Wang, J.,Rachmin, I.,Shapiro, R.,Song, J.,Dagan, A.,Pozo, J.,Kim, S.,Marshall, A.G.,Schimmel, P.,Yang, X.L.,Nechushtan, H.,Razin, E.,Guo, M. Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription. Mol.Cell, 49:30-42, 2013 Cited by PubMed: 23159739DOI: 10.1016/j.molcel.2012.10.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.844 Å) |
Structure validation
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