Author results

2PZE
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MINIMAL HUMAN CFTR FIRST NUCLEOTIDE BINDING DOMAIN AS A HEAD-TO-TAIL DIMER
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Atwell, S., Conners, K., Emtage, S., Gheyi, T., Glenn, N.R., Hendle, J., Lewis, H.A., Lu, F., Rodgers, L.A., Romero, R., Sauder, J.M., Smith, D., Tien, H., Wasserman, S.R., Zhao, X.
Deposit date:2007-05-17
Release date:2007-10-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23, 2010
2PZF
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MINIMAL HUMAN CFTR FIRST NUCLEOTIDE BINDING DOMAIN AS A HEAD-TO-TAIL DIMER WITH DELTA F508
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Atwell, S., Conners, K., Emtage, S., Gheyi, T., Glenn, N.R., Hendle, J., Lewis, H.A., Lu, F., Rodgers, L.A., Romero, R., Sauder, J.M., Smith, D., Tien, H., Wasserman, S.R., Zhao, X.
Deposit date:2007-05-18
Release date:2007-10-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23, 2010
2PZG
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MINIMAL HUMAN CFTR FIRST NUCLEOTIDE BINDING DOMAIN AS A MONOMER
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Atwell, S., Conners, K., Emtage, S., Gheyi, T., Glenn, N.R., Hendle, J., Lewis, H.A., Lu, F., Rodgers, L.A., Romero, R., Sauder, J.M., Smith, D., Tien, H., Wasserman, S.R., Zhao, X.
Deposit date:2007-05-18
Release date:2007-10-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23, 2010
2GDQ
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CRYSTAL STRUCTURE OF MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME FROM BACILLUS SUBTILIS AT 1.8 A RESOLUTION
Descriptor:yitF
Authors:Malashkevich, V.N., Toro, R., Sauder, J.M., Schwinn, K.D., Emtage, S., Thompson, D.A., Rutter, M.E., Dickey, M., Groshong, C., Bain, K.T., Adams, J.M., Reyes, C., Rooney, I., Powell, A., Boice, A., Gheyi, T., Ozyurt, S., Atwell, S., Wasserman, S.R., Burley, S.K., Sali, A., Babbitt, P., Pieper, U., Gerlt, J.A., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-03-16
Release date:2006-04-04
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of mandelate racemase/muconate lactonizing enzyme from Bacillus subtilis at 1.8 A resolution
To be Published
2GGE
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CRYSTAL STRUCTURE OF MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME FROM BACILLUS SUBTILIS COMPLEXED WITH MG++ AT 1.8 A
Descriptor:yitF, MAGNESIUM ION, CHLORIDE ION
Authors:Malashkevich, V.N., Sauder, J.M., Schwinn, K.D., Emtage, S., Thompson, D.A., Rutter, M.E., Dickey, M., Groshong, C., Bain, K.T., Adams, J.M., Reyes, C., Rooney, I., Powell, A., Boice, A., Gheyi, T., Ozyurt, S., Atwell, S., Wasserman, S.R., Burley, S.K., Sali, A., Babbitt, P., Pieper, U., Gerlt, J.A., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-03-23
Release date:2006-04-18
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal Structure of Mandelate Racemase/Muconate Lactonizing Enzyme from Bacillus Subtilis complexed with MG++ at 1.8 A
To be Published
2HHL
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CRYSTAL STRUCTURE OF THE HUMAN SMALL CTD PHOSPHATASE 3 ISOFORM 1
Descriptor:CTD small phosphatase-like protein, 12-TUNGSTOPHOSPHATE
Authors:Malashkevich, V.N., Toro, R., Ramagopal, U., Sauder, J.M., Schwinn, K.D., Thompson, D.A., Rutter, M.E., Dickey, M., Groshong, C., Bain, K.T., Adams, J.M., Reyes, C., Rooney, I., Powell, A., Boice, A., Gheyi, T., Ozyurt, S., Atwell, S., Wasserman, S.R., Emtage, S., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-06-28
Release date:2006-08-29
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
2IJQ
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CRYSTAL STRUCTURE OF PROTEIN RRNAC1037 FROM HALOARCULA MARISMORTUI, PFAM DUF309
Descriptor:Hypothetical protein
Authors:Malashkevich, V.N., Toro, R., Sauder, J.M., Schwinn, K.D., Thompson, D.A., Rutter, M.E., Dickey, M., Groshong, C., Bain, K.T., Adams, J.M., Reyes, C., Rooney, I., Powell, A., Boice, A., Gheyi, T., Ozyurt, S., Atwell, S., Wasserman, S.R., Emtage, S., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-09-30
Release date:2006-10-24
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of the hypothetical Protein from Haloarcula marismortui
To be Published
2O34
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CRYSTAL STRUCTURE OF PROTEIN DVU1097 FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH, PFAM DUF375
Descriptor:Hypothetical protein, SODIUM ION
Authors:Malashkevich, V.N., Toro, R., Sauder, J.M., Schwinn, K.D., Thompson, D.A., Rutter, M.E., Dickey, M., Groshong, C., Bain, K.T., Adams, J.M., Reyes, C., Rooney, I., Powell, A., Boice, A., Gheyi, T., Ozyurt, S., Atwell, S., Wasserman, S.R., Emtage, S., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-11-30
Release date:2006-12-12
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the Hypothetical Protein from Desulfovibrio vulgaris Hildenborough
To be Published
3GD7
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CRYSTAL STRUCTURE OF HUMAN NBD2 COMPLEXED WITH N6-PHENYLETHYL-ATP (P-ATP)
Descriptor:Fusion complex of Cystic fibrosis transmembrane conductance regulator, residues 1193-1427 and Maltose/maltodextrin import ATP-binding protein malK, residues 219-371, ...
Authors:Atwell, S., Antonysamy, S., Conners, K., Emtage, S., Gheyi, T., Lewis, H.A., Lu, F., Sauder, J.M., Wasserman, S.R., Zhao, X.
Deposit date:2009-02-23
Release date:2010-03-02
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human NBD2 complexed with N6-Phenylethyl-ATP (P-ATP)
To be Published
4WUY
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CRYSTAL STRUCTURE OF PROTEIN LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH LLY-507, A CELL-ACTIVE, POTENT AND SELECTIVE INHIBITOR
Descriptor:N-lysine methyltransferase SMYD2, 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Nguyen, H., Allali-Hassani, A., Antonysamy, S., Chang, S., Chen, L.H., Curtis, C., Emtage, S., Fan, L., Gheyi, T., Li, F., Liu, S., Martin, J.R., Mendel, D., Olsen, J.B., Pelletier, L., Shatseva, T., Wu, S., Zhang, F.F., Arrowsmith, C.H., Brown, P.J., Campbell, R.M., Garcia, B.A., Barsyte-Lovejoy, D., Mader, M., Vedadi, M.
Deposit date:2014-11-04
Release date:2015-04-08
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.
J.Biol.Chem., 290, 2015
3RU0
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COCRYSTAL STRUCTURE OF HUMAN SMYD3 WITH INHIBITOR SINEFUNGIN BOUND
Descriptor:SET and MYND domain-containing protein 3, SINEFUNGIN, ZINC ION
Authors:Foreman, K.W., Brown, M., Park, F., Emtage, S., Harriss, J., Das, C., Zhu, L., Crew, A., Arnold, L., Shaaban, S., Tucker, P.
Deposit date:2011-05-04
Release date:2011-05-18
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3.
Plos One, 6, 2011
4GQB
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CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX
Descriptor:Protein arginine N-methyltransferase 5, Methylosome protein 50, Histone H4 peptide, ...
Authors:Antonysamy, S., Bonday, Z., Campbell, R., Doyle, B., Druzina, Z., Gheyi, T., Han, B., Jungheim, L.N., Qian, Y., Rauch, C., Russell, M., Sauder, J.M., Wasserman, S.R., Weichert, K., Willard, F.S., Zhang, A., Emtage, S.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
1XMI
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CRYSTAL STRUCTURE OF HUMAN F508A NBD1 DOMAIN WITH ATP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lewis, H.A., Zhao, X., Wang, C., Sauder, J.M., Rooney, I., Noland, B.W., Lorimer, D., Kearins, M.C., Conners, K., Condon, B., Maloney, P.C., Guggino, W.B., Hunt, J.F., Emtage, S., Structural GenomiX
Deposit date:2004-10-02
Release date:2004-11-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure
J.Biol.Chem., 280, 2005
1XMJ
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CRYSTAL STRUCTURE OF HUMAN DELTAF508 HUMAN NBD1 DOMAIN WITH ATP
Descriptor:Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lewis, H.A., Zhao, X., Wang, C., Sauder, J.M., Rooney, I., Noland, B.W., Lorimer, D., Kearins, M.C., Conners, K., Condon, B., Maloney, P.C., Guggino, W.B., Hunt, J.F., Emtage, S., Structural GenomiX
Deposit date:2004-10-02
Release date:2004-11-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure
J.Biol.Chem., 280, 2005
2OX7
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CRYSTAL STRUCTURE OF PROTEIN EF1440 FROM ENTEROCOCCUS FAECALIS
Descriptor:Hypothetical protein
Authors:Malashkevich, V.N., Toro, R., Sauder, J.M., Schwinn, K.D., Thompson, D.A., Bain, K.T., Adams, J.M., Reyes, C., Lau, C., Gilmore, J., Rooney, I., Gheyi, T., Wasserman, S.R., Emtage, S., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-02-19
Release date:2007-03-06
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.777 Å)
Cite:Crystal structure of the hypothetical protein from Enterococcus faecalis
To be Published
2P84
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CRYSTAL STRUCTURE OF ORF041 FROM BACTERIOPHAGE 37
Descriptor:ORF041
Authors:Malashkevich, V.N., Toro, R., Sauder, J.M., Schwinn, K.D., Thompson, D.A., Bain, K.T., Adams, J.M., Reyes, C., Lau, C., Gilmore, J., Rooney, I., Wasserman, T., Gheyi, S.R., Emtage, S., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-03-21
Release date:2007-04-03
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the hypothetical protein from Staphylococcus phage 37
To be Published
2FH7
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CRYSTAL STRUCTURE OF THE PHOSPHATASE DOMAINS OF HUMAN PTP SIGMA
Descriptor:Receptor-type tyrosine-protein phosphatase S
Authors:Alvarado, J., Udupi, R., Smith, D., Koss, J., Wasserman, S.R., Ozyurt, S., Atwell, S., Powell, A., Kearins, M.C., Rooney, I., Maletic, M., Bain, K.T., Freeman, J.C., Russell, M., Thompson, D.A., Sauder, J.M., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-12-23
Release date:2006-01-10
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
2HXP
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CRYSTAL STRUCTURE OF THE HUMAN PHOSPHATASE (DUSP9)
Descriptor:Dual specificity protein phosphatase 9, PHOSPHATE ION
Authors:Madegowda, M., Eswaramoorthy, S., Burley, S.K., Swaminathan, S., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-03
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
2I1Y
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CRYSTAL STRUCTURE OF THE PHOSPHATASE DOMAIN OF HUMAN PTP IA-2
Descriptor:Receptor-type tyrosine-protein phosphatase, GLYCEROL
Authors:Faber-Barata, J., Patskovsky, Y., Alvarado, J., Smith, D., Koss, J., Wasserman, S.R., Ozyurt, S., Atwell, S., Powell, A., Kearins, M.C., Maletic, M., Rooney, I., Bain, K.T., Freeman, M., Russell, J.C., Thompson, D.A., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-15
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural genomics of protein phosphatases
J.STRUCT.FUNCT.GENOM., 8, 2007
2I44
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CRYSTAL STRUCTURE OF SERINE-THREONINE PHOSPHATASE 2C FROM TOXOPLASMA GONDII
Descriptor:Serine-threonine phosphatase 2C, CALCIUM ION
Authors:Eswaramoorthy, S., Burley, S.K., Swamianthan, S., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-21
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
1O60
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CRYSTAL STRUCTURE OF KDO-8-PHOSPHATE SYNTHASE
Descriptor:2-dehydro-3-deoxyphosphooctonate aldolase
Authors:Structural GenomiX
Deposit date:2003-10-23
Release date:2003-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1O61
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CRYSTAL STRUCTURE OF A PLP-DEPENDENT ENZYME WITH PLP
Descriptor:aminotransferase, ACETATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Structural GenomiX
Deposit date:2003-10-23
Release date:2003-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1O62
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CRYSTAL STRUCTURE OF THE APO FORM OF A PLP-DEPENDENT ENZYME
Descriptor:aminotransferase, ACETATE ION, BETA-MERCAPTOETHANOL
Authors:Structural GenomiX
Deposit date:2003-10-23
Release date:2003-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project.
Proteins, 60, 2005
1O63
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CRYSTAL STRUCTURE OF AN ATP PHOSPHORIBOSYLTRANSFERASE
Descriptor:ATP phosphoribosyltransferase
Authors:Structural GenomiX
Deposit date:2003-10-23
Release date:2003-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1O64
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CRYSTAL STRUCTURE OF AN ATP PHOSPHORIBOSYLTRANSFERASE
Descriptor:ATP phosphoribosyltransferase, PHOSPHATE ION
Authors:Structural GenomiX
Deposit date:2003-10-23
Release date:2003-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005