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4GQB
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CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX
分子名称:Protein arginine N-methyltransferase 5, Methylosome protein 50, Histone H4 peptide, ...
著者Antonysamy, S., Bonday, Z., Campbell, R., Doyle, B., Druzina, Z., Gheyi, T., Han, B., Jungheim, L.N., Qian, Y., Rauch, C., Russell, M., Sauder, J.M., Wasserman, S.R., Weichert, K., Willard, F.S., Zhang, A., Emtage, S.
登録日2012-08-22
公開日2012-10-17
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
4MI5
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CRYSTAL STRUCTURE OF THE EZH2 SET DOMAIN
分子名称:Histone-lysine N-methyltransferase EZH2, SULFATE ION, ZINC ION
著者Antonysamy, S., Condon, B., Druzina, Z., Bonanno, J., Gheyi, T., Macewan, I., Zhang, A., Ashok, S., Russell, M., Luz, J.G.
登録日2013-08-30
公開日2014-01-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET Domain.
Plos One, 8, 2013
5KN5
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TGFALPHA/EPIREGULIN COMPLEX WITH NEUTRALIZING ANTIBODY LY3016859
分子名称:Epiregulin Antibody LY3016859 Fab Heavy Chain, Epiregulin Antibody LY3016859 Fab Light Chain, Protransforming growth factor alpha, ...
著者Atwell, S., Boyles, J.S., Clawson, D.K., Druzina, Z., Josef, G.H., Weichert, K., Witcher, D.R.
登録日2016-06-27
公開日2016-08-31
最終更新日2016-11-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of selectivity and neutralizing activity of a TGF alpha /epiregulin specific antibody.
Protein Sci., 25, 2016