4E17 | | ALPHA-E-CATENIN IS AN AUTOINHIBITED MOLECULE THAT CO-ACTIVATES VINCULIN | | Descriptor: | Vinculin, Catenin alpha-1 | | Authors: | Choi, H.-J., Pokutta, S., Cadwell, G.W., Bankston, L.A., Liddington, R.C., Weis, W.I. | | Deposit date: | 2012-03-05 | | Release date: | 2012-05-16 | | Method: | X-RAY DIFFRACTION (2.304 Å) | | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
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4E18 | | ALPHA-E-CATENIN IS AN AUTOINHIBITED MOLECULE THAT CO-ACTIVATES VINCULIN | | Descriptor: | Vinculin, Catenin alpha-1 | | Authors: | Choi, H.-J., Pokutta, S., Cadwell, G.W., Bankston, L.A., Liddington, R.C., Weis, W.I. | | Deposit date: | 2012-03-05 | | Release date: | 2012-05-16 | | Method: | X-RAY DIFFRACTION (2.403 Å) | | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
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1PRX | | HORF6 A NOVEL HUMAN PEROXIDASE ENZYME | | Descriptor: | HORF6 | | Authors: | Choi, H.-J., Kang, S.W., Yang, C.-H., Rhee, S.G., Ryu, S.-E. | | Deposit date: | 1998-04-03 | | Release date: | 1998-06-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution.
Nat.Struct.Biol., 5, 1998
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3IFQ | | INTERCTION OF PLAKOGLOBIN AND BETA-CATENIN WITH DESMOSOMAL CADHERINS | | Descriptor: | plakoglobin, E-cadherin, SULFATE ION | | Authors: | Choi, H.-J., Gross, J.C., Pokutta, S., Weis, W.I. | | Deposit date: | 2009-07-24 | | Release date: | 2009-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
J.Biol.Chem., 284, 2009
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3R6N | | CRYSTAL STRUCTURE OF A RIGID FOUR SPECTRIN REPEAT FRAGMENT OF THE HUMAN DESMOPLAKIN PLAKIN DOMAIN | | Descriptor: | Desmoplakin, (4S,5S)-1,2-DITHIANE-4,5-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE | | Authors: | Choi, H.-J., Weis, W.I. | | Deposit date: | 2011-03-22 | | Release date: | 2011-05-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal structure of a rigid four-spectrin-repeat fragment of the human desmoplakin plakin domain.
J.Mol.Biol., 409, 2011
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4R0Z | | A CONSERVED PHOSPHORYLATION SWITCH CONTROLS THE INTERACTION BETWEEN CADHERIN AND BETA-CATENIN IN VITRO AND IN VIVO | | Descriptor: | Protein humpback-2, FORMIC ACID | | Authors: | Choi, H.-J., Loveless, T., Lynch, A., Bang, I., Hardin, J., Weis, W.I. | | Deposit date: | 2014-08-03 | | Release date: | 2015-04-29 | | Method: | X-RAY DIFFRACTION (2.005 Å) | | Cite: | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
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4R10 | | A CONSERVED PHOSPHORYLATION SWITCH CONTROLS THE INTERACTION BETWEEN CADHERIN AND BETA-CATENIN IN VITRO AND IN VIVO | | Descriptor: | Protein humpback-2, Cadherin-related hmr-1, SULFATE ION, ... | | Authors: | Choi, H.-J., Loveless, T., Lynch, A., Bang, I., Hardin, J., Weis, W.I. | | Deposit date: | 2014-08-03 | | Release date: | 2015-04-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
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4R11 | | A CONSERVED PHOSPHORYLATION SWITCH CONTROLS THE INTERACTION BETWEEN CADHERIN AND BETA-CATENIN IN VITRO AND IN VIVO | | Descriptor: | Protein humpback-2, Cadherin-related hmr-1, IODIDE ION | | Authors: | Choi, H.-J., Loveless, T., Lynch, A., Bang, I., Hardin, J., Weis, W.I. | | Deposit date: | 2014-08-03 | | Release date: | 2015-04-29 | | Method: | X-RAY DIFFRACTION (2.789 Å) | | Cite: | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
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5DZZ | |
1ATU | | UNCLEAVED ALPHA-1-ANTITRYPSIN | | Descriptor: | ALPHA-1-ANTITRYPSIN | | Authors: | Ryu, S.-E., Choi, H.-J. | | Deposit date: | 1997-05-11 | | Release date: | 1997-08-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
Structure, 4, 1996
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3KJ6 | | CRYSTAL STRUCTURE OF A METHYLATED BETA2 ADRENERGIC RECEPTOR-FAB COMPLEX | | Descriptor: | Beta-2 adrenergic receptor, Fab light chain, Fab heavy chain, ... | | Authors: | Bokoch, M.P., Zou, Y., Rasmussen, S.G.F., Liu, C.W., Nygaard, R., Rosenbaum, D.M., Fung, J.J., Choi, H.-J., Thian, F.S., Kobilka, T.S., Puglisi, J.D., Weis, W.I., Pardo, L., Prosser, S., Mueller, L., Kobilka, B.K. | | Deposit date: | 2009-11-02 | | Release date: | 2010-02-16 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
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3P0G | | STRUCTURE OF A NANOBODY-STABILIZED ACTIVE STATE OF THE BETA2 ADRENOCEPTOR | | Descriptor: | Beta-2 adrenergic receptor, Lysozyme, Camelid Antibody Fragment, ... | | Authors: | Rasmussen, S.G.F., Choi, H.-J., Fung, J.J., Pardon, E., Casarosa, P., Chae, P.S., DeVree, B.T., Rosenbaum, D.M., Thian, F.S., Kobilka, T.S., Schnapp, A., Konetzki, I., Sunahara, R.K., Gellman, S.H., Pautsch, A., Steyaert, J., Weis, W.I., Kobilka, B.K. | | Deposit date: | 2010-09-28 | | Release date: | 2011-01-19 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
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3PDS | | IRREVERSIBLE AGONIST-BETA2 ADRENOCEPTOR COMPLEX | | Descriptor: | Fusion protein Beta-2 adrenergic receptor/Lysozyme, 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, ... | | Authors: | Rosenbaum, D.M., Zhang, C., Lyons, J.A., Holl, R., Aragao, D., Arlow, D.H., Rasmussen, S.G.F., Choi, H.-J., DeVree, B.T., Sunahara, R.K., Chae, P.S., Gellman, S.H., Dror, R.O., Shaw, D.E., Weis, W.I., Caffrey, M., Gmeiner, P., Kobilka, B.K. | | Deposit date: | 2010-10-24 | | Release date: | 2011-01-12 | | Last modified: | 2017-07-26 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
Nature, 469, 2011
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3S2K | | STRUCTURAL BASIS OF WNT SIGNALING INHIBITION BY DICKKOPF BINDING TO LRP5/6. | | Descriptor: | Low-density lipoprotein receptor-related protein 6, Dickkopf-related protein 1, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Ahn, V.E., Chu, M.L.-H., Choi, H.-J., Tran, D., Abo, A., Weis, W.I. | | Deposit date: | 2011-05-16 | | Release date: | 2011-11-02 | | Last modified: | 2011-12-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6.
Dev.Cell, 21, 2011
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4KRR | | CRYSTAL STRUCTURE OF DROSOPHILA WNTD N-TERMINAL DOMAIN-LINKER (RESIDUES 31-240) | | Descriptor: | Wnt inhibitor of Dorsal protein, GLYCEROL, SODIUM ION | | Authors: | Chu, M.L.-H., Choi, H.-J., Ahn, V.E., Daniels, D.L., Nusse, R., Weis, W.I. | | Deposit date: | 2013-05-16 | | Release date: | 2013-07-10 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (2.124 Å) | | Cite: | Structural Studies of Wnts and Identification of an LRP6 Binding Site.
Structure, 21, 2013
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4ONS | | STRUCTURAL AND THERMODYNAMIC CHARACTERIZATION OF CADHERIN-BETA-CATENIN-ALPHA-CATENIN COMPLEX FORMATION | | Descriptor: | Catenin alpha-2, Catenin beta-1 | | Authors: | Pokutta, S., Choi, H.-J., Ahlsen, G., Hansen, S.D., Weis, W.I. | | Deposit date: | 2014-01-29 | | Release date: | 2014-04-09 | | Last modified: | 2014-05-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and Thermodynamic Characterization of Cadherin beta-Catenin alpha-Catenin Complex Formation.
J.Biol.Chem., 289, 2014
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5ZJD | | LACTATE DEHYDROGENASE WITH NADH AND MLA | | Descriptor: | L-lactate dehydrogenase A chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MALONATE ION | | Authors: | Han, C.W., Jang, S.B. | | Deposit date: | 2018-03-20 | | Release date: | 2019-07-24 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.394 Å) | | Cite: | Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
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5ZJE | | LDHA-MLA | | Descriptor: | L-lactate dehydrogenase A chain, MALONATE ION | | Authors: | Han, C.W., Jang, S.B. | | Deposit date: | 2018-03-20 | | Release date: | 2019-07-24 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.929 Å) | | Cite: | Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
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5ZJF | | LDHA-MA | | Descriptor: | L-lactate dehydrogenase A chain, 5,5'-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2H-1,3-benzodioxole) | | Authors: | Han, C.W., Jang, S.B. | | Deposit date: | 2018-03-20 | | Release date: | 2019-07-24 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
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