4E17
 
 | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | Descriptor: | Catenin alpha-1, Vinculin | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | Deposit date: | 2012-03-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin To be Published
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4E18
 
 | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | Descriptor: | Catenin alpha-1, Vinculin | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | Deposit date: | 2012-03-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin To be Published
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6L6R
 
 | Crystal structure of LRP6 E1E2-SOST complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Choi, H.-J, Kim, J. | Deposit date: | 2019-10-29 | Release date: | 2020-10-28 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains. Nat Commun, 11, 2020
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5DZZ
 
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3R6N
 
 | Crystal structure of a rigid four spectrin repeat fragment of the human desmoplakin plakin domain | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Desmoplakin | Authors: | Choi, H.-J, Weis, W.I. | Deposit date: | 2011-03-22 | Release date: | 2011-05-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of a rigid four-spectrin-repeat fragment of the human desmoplakin plakin domain. J.Mol.Biol., 409, 2011
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4R0Z
 
 | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | Descriptor: | FORMIC ACID, Protein humpback-2 | Authors: | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | Deposit date: | 2014-08-03 | Release date: | 2015-04-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
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4R10
 
 | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | Descriptor: | 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ... | Authors: | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | Deposit date: | 2014-08-03 | Release date: | 2015-04-29 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
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4R11
 
 | A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo | Descriptor: | Cadherin-related hmr-1, IODIDE ION, Protein humpback-2 | Authors: | Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. | Deposit date: | 2014-08-03 | Release date: | 2015-04-29 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.789 Å) | Cite: | A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
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1PRX
 
 | HORF6 A NOVEL HUMAN PEROXIDASE ENZYME | Descriptor: | HORF6 | Authors: | Choi, H.-J, Kang, S.W, Yang, C.-H, Rhee, S.G, Ryu, S.-E. | Deposit date: | 1998-04-03 | Release date: | 1998-06-17 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution. Nat.Struct.Biol., 5, 1998
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3IFQ
 
 | Interction of plakoglobin and beta-catenin with desmosomal cadherins | Descriptor: | E-cadherin, SULFATE ION, plakoglobin | Authors: | Choi, H.-J, Gross, J.C, Pokutta, S, Weis, W.I. | Deposit date: | 2009-07-24 | Release date: | 2009-09-15 | Last modified: | 2024-11-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes. J.Biol.Chem., 284, 2009
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8W77
 
 | Human Consensus Olfactory Receptor OR52c in apo state, OR52c only | Descriptor: | Human Consensus Olfactory Receptor OR52c in apo state, receptor only,Soluble cytochrome b562 | Authors: | Choi, C.W, Bae, J, Choi, H.-J, Kim, J. | Deposit date: | 2023-08-30 | Release date: | 2023-12-20 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family. Nat Commun, 14, 2023
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8HTI
 
 | Human Consensus Olfactory Receptor OR52c in Complex with Octanoic Acid (OCA) and G Protein | Descriptor: | Consensus Olfactory Receptor OR52c, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Choi, C.W, Bae, J, Choi, H.-J, Kim, J. | Deposit date: | 2022-12-21 | Release date: | 2023-12-20 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family. Nat Commun, 14, 2023
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9IPY
 
 | Structure of JR14a-bound human C3aR | Descriptor: | (2~{S})-5-[bis(azanyl)methylideneamino]-2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-thiophen-2-yl]carbonylamino]pentanoic acid, C3a anaphylatoxin chemotactic receptor,Soluble cytochrome b562 | Authors: | Kim, J, Ko, S, Choi, H.-J. | Deposit date: | 2024-07-12 | Release date: | 2025-04-23 | Last modified: | 2025-07-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into small-molecule agonist recognition and activation of complement receptor C3aR. Embo J., 44, 2025
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9ISI
 
 | Structure of human C3aR in apo state | Descriptor: | C3a anaphylatoxin chemotactic receptor,Soluble cytochrome b562 | Authors: | Kim, J, Ko, S, Choi, H.-J. | Deposit date: | 2024-07-17 | Release date: | 2025-04-23 | Last modified: | 2025-07-16 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structural insights into small-molecule agonist recognition and activation of complement receptor C3aR. Embo J., 44, 2025
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9IPV
 
 | Structure of JR14a-C3aR-Gi-scFv16 complex | Descriptor: | (2~{S})-5-[bis(azanyl)methylideneamino]-2-[[5-[bis(4-chlorophenyl)methyl]-3-methyl-thiophen-2-yl]carbonylamino]pentanoic acid, C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Kim, J, Ko, S, Choi, H.-J. | Deposit date: | 2024-07-11 | Release date: | 2025-04-23 | Last modified: | 2025-06-04 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Structural insights into small-molecule agonist recognition and activation of complement receptor C3aR. Embo J., 44, 2025
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8J46
 
 | Human Consensus Olfactory Receptor OR52c in apo state, OR52c-bRIL | Descriptor: | Olfactory receptor OR52c,Soluble cytochrome b562 | Authors: | Choi, C.W, Bae, J, Choi, H.-J, Kim, J. | Deposit date: | 2023-04-19 | Release date: | 2023-12-20 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family. Nat Commun, 14, 2023
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7YON
 
 | Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Kang, H, Park, C, Kim, J, Choi, H.-J. | Deposit date: | 2022-08-01 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
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7YOO
 
 | Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Kang, H, Park, C, Kim, J, Choi, H.-J. | Deposit date: | 2022-08-01 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
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8HTG
 
 | Crystal structure of Golf in complex with GTP-gamma S and Mg | Descriptor: | 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(olf) subunit alpha, ... | Authors: | Kang, H, Choi, H.-J. | Deposit date: | 2022-12-21 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family. Nat Commun, 14, 2023
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3S2K
 
 | Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ahn, V.E, Chu, M.L.-H, Choi, H.-J, Tran, D, Abo, A, Weis, W.I. | Deposit date: | 2011-05-16 | Release date: | 2011-11-02 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6. Dev.Cell, 21, 2011
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9JFY
 
 | Cryo-EM structure of Neuropeptide FF receptor 2 in complex with hNPSF and Gi | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Kim, J, Choi, H.-J. | Deposit date: | 2024-09-05 | Release date: | 2025-04-09 | Last modified: | 2025-06-18 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structural insights into the selective recognition of RF-amide peptides by neuropeptide FF receptor 2. Embo Rep., 26, 2025
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9JG0
 
 | Cryo-EM structure of neuropeptide FF receptor 2 in the ligand-free state with BRIL fusion, anti-BRIL Fab, and nanobody | Descriptor: | Anti-BRIL fab heavy chain, Anti-BRIL fab light chain, Anti-fab nanobody, ... | Authors: | Kim, J, Choi, H.-J. | Deposit date: | 2024-09-05 | Release date: | 2025-04-09 | Last modified: | 2025-07-02 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Structural insights into the selective recognition of RF-amide peptides by neuropeptide FF receptor 2. Embo Rep., 26, 2025
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8JWS
 
 | ePHD domain of PHD Finger Protein 7 (PHF7) | Descriptor: | 1,2-ETHANEDIOL, PHD finger protein 7, ZINC ION | Authors: | Bang, I, Lee, H.S, Choi, H.-J. | Deposit date: | 2023-06-29 | Release date: | 2023-12-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for PHF7-mediated ubiquitination of histone H3. Genes Dev., 37, 2023
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8JWJ
 
 | PHD Finger Protein 7 (PHF7) in complex with UBE2D2 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHD finger protein 7, ... | Authors: | Lee, H.S, Bang, I, Choi, H.-J. | Deposit date: | 2023-06-29 | Release date: | 2023-12-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Molecular basis for PHF7-mediated ubiquitination of histone H3. Genes Dev., 37, 2023
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8JWU
 
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