Author results

1FHI
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SUBSTRATE ANALOG (IB2) COMPLEX WITH THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT
分子名称:FRAGILE HISTIDINE TRIAD PROTEIN, P1-P2-METHYLENE-P3-THIO-DIADENOSINE TRIPHOSPHATE
著者Pace, H.C., Garrison, P.N., Barnes, L.D., Draganescu, A., Rosler, A., Blackburn, G.M., Siprashvili, Z., Croce, C.M., Huebner, K., Brenner, C.
登録日1997-12-11
公開日1998-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
Proc.Natl.Acad.Sci.USA, 95, 1998
1KTG
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CRYSTAL STRUCTURE OF A C. ELEGANS AP4A HYDROLASE BINARY COMPLEX
分子名称:Diadenosine Tetraphosphate Hydrolase, PHOSPHATE ION, HYDROXIDE ION, ...
著者Bailey, S., Sedelnikova, S.E., Blackburn, G.M., Abdelghany, H.M., Baker, P.J., McLennan, A.G., Rafferty, J.B.
登録日2002-01-16
公開日2002-05-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms
Structure, 10, 2002
2FHI
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SUBSTRATE ANALOG (IB2) COMPLEX WITH THE HIS 96 ASN SUBSTITUTION OF THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT
分子名称:FRAGILE HISTIDINE TRIAD PROTEIN, P1-P2-METHYLENE-P3-THIO-DIADENOSINE TRIPHOSPHATE
著者Pace, H.C., Garrison, P.N., Robinson, A.K., Barnes, L.D., Draganescu, A., Rosler, A., Blackburn, G.M., Siprashvili, Z., Croce, C.M., Heubner, K., Brenner, C.
登録日1998-04-01
公開日1998-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
Proc.Natl.Acad.Sci.USA, 95, 1998
1EMH
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CRYSTAL STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE BOUND TO UNCLEAVED SUBSTRATE-CONTAINING DNA
分子名称:DNA (5'-D(*TP*GP*TP*(P2U)P*AP*TP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*A)-3'), URACIL-DNA GLYCOSYLASE
著者Parikh, S.S., Slupphaug, G., Krokan, H.E., Blackburn, G.M., Tainer, J.A.
登録日2000-03-16
公開日2000-05-16
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EMJ
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URACIL-DNA GLYCOSYLASE BOUND TO DNA CONTAINING A 4'-THIO-2'DEOXYURIDINE ANALOG PRODUCT
分子名称:DNA (5'-D(*TP*GP*TP*(ASU)P*AP*TP*CP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*A)-3'), URACIL-DNA GLYCOSYLASE, ...
著者Parikh, S.S., Walcher, G., Jones, G.D., Slupphaug, G., Krokan, H.E., Blackburn, G.M., Tainer, J.A.
登録日2000-03-16
公開日2000-05-16
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects.
Proc.Natl.Acad.Sci.USA, 97, 2000
1F3Y
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SOLUTION STRUCTURE OF THE NUDIX ENZYME DIADENOSINE TETRAPHOSPHATE HYDROLASE FROM LUPINUS ANGUSTIFOLIUS L.
分子名称:DIADENOSINE 5',5'''-P1,P4-TETRAPHOSPHATE HYDROLASE
著者Swarbrick, J.D., Bashtannyk, T., Maksel, D., Zhang, X.R., Blackburn, G.M., Gayler, K.R., Gooley, P.R.
登録日2000-06-06
公開日2001-06-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of the Nudix enzyme diadenosine tetraphosphate hydrolase from Lupinus angustifolius L.
J.Mol.Biol., 302, 2000
1H3I
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CRYSTAL STRUCTURE OF THE HISTONE METHYLTRANSFERASE SET7/9
分子名称:HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE, MAGNESIUM ION
著者Wilson, J.R., Jing, C., Walker, P.A., Martin, S.R., Howell, S.A., Blackburn, G.M., Gamblin, S.J., Xiao, B.
登録日2002-09-04
公開日2002-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9
Cell(Cambridge,Mass.), 111, 2002
1J98
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THE 1.2 ANGSTROM STRUCTURE OF BACILLUS SUBTILIS LUXS
分子名称:AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION
著者Ruzheinikov, S.N., Das, S.K., Sedelnikova, S.E., Hartley, A., Foster, S.J., Horsburgh, M.J., Cox, A.G., McCleod, C.W., Mekhalfia, A., Blackburn, G.M., Rice, D.W., Baker, P.J.
登録日2001-05-24
公開日2001-06-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The 1.2 A Structure of a Novel Quorum-Sensing Protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
1JQW
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THE 2.3 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/HOMOCYSTEINE COMPLEX
分子名称:Autoinducer-2 production protein luxS, ZINC ION, 2-AMINO-4-MERCAPTO-BUTYRIC ACID
著者Ruzheinikov, S.N., Das, S.K., Sedelnikova, S.E., Hartley, A., Foster, S.J., Horsburgh, M.J., Cox, A.G., McCleod, C.W., Mekhalfia, A., Blackburn, G.M., Rice, D.W., Baker, P.J.
登録日2001-08-09
公開日2001-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
1JVI
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THE 2.2 ANGSTROM RESOLUTION STRUCTURE OF BACILLUS SUBTILIS LUXS/RIBOSILHOMOCYSTEINE COMPLEX
分子名称:Autoinducer-2 production protein luxS, ZINC ION, SULFATE ION, ...
著者Ruzheinikov, S.N., Das, S.K., Sedelnikova, S.E., Hartley, A., Foster, S.J., Horsburgh, M.J., Cox, A.G., McCleod, C.W., Mekhalfia, A., Blackburn, G.M., Rice, D.W., Baker, P.J.
登録日2001-08-30
公開日2001-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS
J.Mol.Biol., 313, 2001
1KT9
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CRYSTAL STRUCTURE OF C. ELEGANS AP4A HYDROLASE
分子名称:Diadenosine Tetraphosphate Hydrolase
著者Bailey, S., Sedelnikova, S.E., Blackburn, G.M., Abdelghany, H.M., Baker, P.J., McLennan, A.G., Rafferty, J.B.
登録日2002-01-15
公開日2002-05-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms
Structure, 10, 2002
1MH5
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THE STRUCTURE OF THE COMPLEX OF THE FAB FRAGMENT OF THE ESTEROLYTIC ANTIBODY MS6-164 AND A TRANSITION-STATE ANALOG
分子名称:IMMUNOGLOBULIN MS6-164, SULFATE ION, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE
著者Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W.
登録日2002-08-19
公開日2003-09-23
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
1MIE
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS5-393
分子名称:IMMUNOGLOBULIN MS5-393
著者Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W.
登録日2002-08-23
公開日2003-09-23
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
1MJ7
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS5-393 AND A TRANSITION-STATE ANALOG
分子名称:IMMUNOGLOBULIN MS5-393, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE
著者Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W.
登録日2002-08-27
公開日2003-09-23
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
1MJ8
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF THE ESTEROLYTIC ANTIBODY MS6-126
分子名称:IMMUNOGLOBULIN MS6-126, PHOSPHATE ION, GLYCEROL
著者Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W.
登録日2002-08-27
公開日2003-09-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
1MJJ
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12 AND A TRANSITION-STATE ANALOG
分子名称:IMMUNOGLOBULIN MS6-12, SULFATE ION, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE
著者Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W.
登録日2002-08-28
公開日2003-09-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
1MJU
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1.22 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12
分子名称:IMMUNOGLOBULIN MS6-12, GLYCEROL
著者Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W.
登録日2002-08-28
公開日2003-09-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
1O9S
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE SET7/9
分子名称:HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, GENE FRAGMENT FOR HISTONE H3, ...
著者Xiao, B., Jing, C., Wilson, J.R., Walker, P.A., Vasisht, N., Kelly, G., Howell, S., Taylor, I.A., Blackburn, G.M., Gamblin, S.J.
登録日2002-12-18
公開日2003-02-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9
Nature, 421, 2003
1RZY
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CRYSTAL STRUCTURE OF RABBIT HINT COMPLEXED WITH N-ETHYLSULFAMOYLADENOSINE
分子名称:Histidine triad nucleotide-binding protein 1, 5'-O-(N-ETHYL-SULFAMOYL)ADENOSINE
著者Krakowiak, A.K., Pace, H.C., Blackburn, G.M., Adams, M., Mekhalfia, A., Kaczmarek, R., Baraniak, J., Stec, W.J., Brenner, C.
登録日2003-12-29
公開日2004-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors
J.Biol.Chem., 279, 2004
1X7N
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THE CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS PHOSPHOGLUCOSE ISOMERASE WITH BOUND 5-PHOSPHO-D-ARABINONATE AND MANGANESE
分子名称:Glucose-6-phosphate isomerase, MANGANESE (II) ION, 5-PHOSPHOARABINONIC ACID
著者Berrisford, J.M., Akerboom, J., Brouns, S., Sedelnikova, S.E., Turnbull, A.P., van der Oost, J., Salmon, L., Hardre, R., Murray, I.A., Blackburn, G.M., Rice, D.W., Baker, P.J.
登録日2004-08-16
公開日2004-10-12
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X82
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CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE FROM PYROCOCCUS FURIOSUS WITH BOUND 5-PHOSPHO-D-ARABINONATE
分子名称:Glucose-6-phosphate isomerase, 5-PHOSPHOARABINONIC ACID
著者Berrisford, J.M., Akerboom, J., Brouns, S., Sedelnikova, S.E., Turnbull, A.P., van der Oost, J., Salmon, L., Hardre, R., Murray, I.A., Blackburn, G.M., Rice, D.W., Baker, P.J.
登録日2004-08-17
公開日2004-10-12
最終更新日2014-09-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X8E
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CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS PHOSPHOGLUCOSE ISOMERASE FREE ENZYME
分子名称:Glucose-6-phosphate isomerase
著者Berrisford, J.M., Akerboom, J., Brouns, S., Sedelnikova, S.E., Turnbull, A.P., van der Oost, J., Salmon, L., Hardre, R., Murray, I.A., Blackburn, G.M., Rice, D.W., Baker, P.J.
登録日2004-08-18
公開日2004-10-12
最終更新日2014-09-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
2AIO
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METALLO BETA LACTAMASE L1 FROM STENOTROPHOMONAS MALTOPHILIA COMPLEXED WITH HYDROLYZED MOXALACTAM
分子名称:Metallo-beta-lactamase L1, ZINC ION, SULFATE ION, ...
著者Spencer, J., Read, J., Sessions, R.B., Howell, S., Blackburn, G.M., Gamblin, S.J.
登録日2005-07-30
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Antibiotic Recognition by Binuclear Metallo-beta-Lactamases Revealed by X-ray Crystallography
J.Am.Chem.Soc., 127, 2005
2EU2
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, (R)-1-AMINO-1-[5-(DIMETHYLAMINO)-1,3,4-THIADIAZOL-2-YL]METHANESULFONAMIDE
著者Fisher, S.Z., Govindasamy, L., Boyle, N., Agbandje-McKenna, M., Silverman, D.N., Blackburn, G.M., McKenna, R.
登録日2005-10-28
公開日2006-07-11
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes.
Acta Crystallogr.,Sect.F, 62, 2006
2EU3
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH NOVEL INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, 1-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1,1-DIFLUOROMETHANESULFONAMIDE
著者Fisher, S.Z., Govindasamy, L., Boyle, N., Agbandje-McKenna, M., Silverman, D.N., Blackburn, G.M., McKenna, R.
登録日2005-10-28
公開日2006-07-11
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes.
Acta Crystallogr.,Sect.F, 62, 2006
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