5ADP

Crystal structure of the A.17 antibody FAB fragment - Light chain S35R mutant

Summary for 5ADP

• Entry DOI: 10.2210/pdb5adp/pdb
• Related: 5ADO
• Descriptor: FAB A.17 (3 entities in total)
• Functional Keywords: immune system, enzyme reprogramming, antibodies, ig superfamily, in silico antibody maturation
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 54077.62

Authors

Chatziefthimiou, S.D.,Smirnov, I.V.,Golovin, A.V.,Stepanova, A.V.,Peng, Y.,Zolotareva, O.I.,Belogurov, A.A.,Ponomarenko, N.A.,Blackburn, G.M.,Gabibov, A.A.,Lerner, R.,Wilmanns, M. (deposition date: 2015-08-21, release date: 2016-11-09, Last modification date: 2024-01-10)

• Primary citation: Smirnov, I.V.,Golovin, A.V.,Chatziefthimiou, S.D.,Stepanova, A.V.,Peng, Y.,Zolotareva, O.I.,Belogurov, A.A.,Kurkova, I.N.,Ponomarenko, N.A.,Wilmanns, M.,Blackburn, G.M.,Gabibov, A.G.,Lerner, R.A.; Robotic Qm/Mm-Driven Maturation of Antibody Combining Sites.; Sci.Adv., 2:01695-, 2016; PubMed: 27774510; DOI: 10.1126/SCIADV.1501695

Experimental method

X-RAY DIFFRACTION (2.13 Å)