Author results

3SRY
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ENGINEERED HIGH-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: HALIDE-FREE
Descriptor:Green fluorescent protein
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-07
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.159 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3ST0
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ENGINEERED MEDIUM-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: HALIDE-FREE
Descriptor:Green fluorescent protein, 1,2-ETHANEDIOL, FORMIC ACID
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
3SSH
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ENGINEERED HIGH-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: CHLORIDE COMPLEX
Descriptor:Green fluorescent protein, CHLORIDE ION
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.277 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SVB
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ENGINEERED MEDIUM-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: FLUORIDE COMPLEX
Descriptor:Green fluorescent protein, 1,2-ETHANEDIOL
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SVC
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ENGINEERED MEDIUM-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: CHLORIDE COMPLEX
Descriptor:Green fluorescent protein, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
2HPH
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HIGH RESOLUTION STRUCTURE OF E. COLI GLUCOSE/GALACTOSE BINDING PROTEIN BOUND WITH GLUCOSE
Descriptor:D-galactose-binding periplasmic protein, BETA-D-GLUCOSE, CALCIUM ION
Authors:Cuneo, M.J., Hellinga, H.W.
Deposit date:2006-07-17
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:High resolution structure of E. coli glucose/galactose binding protein bound with glucose
To be Published
3SSK
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ENGINEERED HIGH-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: BROMIDE COMPLEX
Descriptor:Green fluorescent protein, BROMIDE ION
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.361 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
2FN9
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THERMOTOGA MARITIMA RIBOSE BINDING PROTEIN UNLIGANDED FORM
Descriptor:ribose ABC transporter, periplasmic ribose-binding protein
Authors:Cuneo, M.J., Changela, A., Tian, Y., Beese, L.S., Hellinga, H.W.
Deposit date:2006-01-10
Release date:2007-01-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Ligand-induced conformational changes in a thermophilic ribose-binding protein.
Bmc Struct.Biol., 8, 2008
3SST
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ENGINEERED LOW-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: CHLORIDE COMPLEX
Descriptor:Green fluorescent protein, CHLORIDE ION
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.403 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SSL
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ENGINEERED HIGH-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: IODIDE COMPLEX
Descriptor:Green fluorescent protein, IODIDE ION
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be published
4L9P
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CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE FII ANALOG, FPT-II, AND THE KCVVM PEPTIDE
Descriptor:CaaX farnesyltransferase alpha subunit Ram2, CaaX farnesyltransferase beta subunit Ram1, LYS-CYS-VAL-VAL-MET (CAAX peptide), ...
Authors:Mabanglo, M.F., Hast, M.A., Beese, L.S.
Deposit date:2013-06-18
Release date:2014-01-01
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.
Protein Sci., 23, 2014
3SS0
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ENGINEERED HIGH-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: FLUORIDE COMPLEX
Descriptor:Green fluorescent protein
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-07
Release date:2012-07-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SVE
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ENGINEERED LOW-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: BROMIDE COMPLEX
Descriptor:Green fluorescent protein, BROMIDE ION
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
2H6F
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PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYLATED DDPTASACVLS PEPTIDE PRODUCT AT 1.5A RESOLUTION
Descriptor:Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein farnesyltransferase beta subunit, farnesylated peptide, ...
Authors:Terry, K.L., Beese, L.S.
Deposit date:2006-05-31
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2O7I
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THE X-RAY CRYSTAL STRUCTURE OF A THERMOPHILIC CELLOBIOSE BINDING PROTEIN BOUND WITH CELLOBIOSE
Descriptor:Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, CELLOBIOSE
Authors:Cuneo, M.J., Hellinga, H.W.
Deposit date:2006-12-11
Release date:2007-03-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold.
J.Biol.Chem., 284, 2009
3I5O
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THE X-RAY CRYSTAL STRUCTURE OF A THERMOPHILIC CELLOBIOSE BINDING PROTEIN BOUND WITH CELLOPENTAOSE
Descriptor:Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, BETA-D-GLUCOSE
Authors:Cuneo, M.J., Hellinga, H.W.
Deposit date:2009-07-06
Release date:2009-07-21
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold.
J.Biol.Chem., 284, 2009
4YFU
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CRYSTAL STRUCTURE OF OPEN BACILLUS FRAGMENT DNA POLYMERASE BOUND TO DNA AND DTTP
Descriptor:DNA polymerase, Primer DNA, Template DNA, ...
Authors:Wu, E.Y.
Deposit date:2015-02-25
Release date:2015-07-22
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Closing Mechanism of DNA Polymerase I at Atomic Resolution.
Structure, 23, 2015
3PV8
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CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT BOUND TO DNA AND DDTTP-DA IN CLOSED CONFORMATION
Descriptor:DNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(2DT))-3'), DNA (5'-D(*C*AP*TP*AP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2010-12-06
Release date:2011-10-19
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SV5
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ENGINEERED MEDIUM-AFFINITY HALIDE-BINDING PROTEIN DERIVED FROM YFP: IODIDE COMPLEX
Descriptor:Green fluorescent protein, 1,2-ETHANEDIOL, IODIDE ION, ...
Authors:Wang, W., Grimley, J.S., Beese, L.S., Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
3TAN
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CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT BOUND TO DUPLEX DNA WITH CYTOSINE-ADENINE MISMATCH AT (N-1) POSITION
Descriptor:DNA polymerase I, 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*C)-3', 5'-D(*GP*AP*CP*GP*T*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', ...
Authors:Wang, W., Beese, L.S.
Deposit date:2011-08-04
Release date:2011-10-19
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
2HHV
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T:O6-METHYL-GUANINE IN THE POLYMERASE-2 BASEPAIR POSITION
Descriptor:5'-D(*GP*CP*GP*AP*TP*CP*AP*GP*CP*TP*TP*G)-3', 5'-D(*GP*TP*AP*CP*(6OG)P*AP*GP*CP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ...
Authors:Warren, J.J., Forsberg, L.J., Beese, L.S.
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The structural basis for the mutagenicity of O6-methyl-guanine lesions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2B3F
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THERMUS THERMOPHILUS GLUCOSE/GALACTOSE BINDING PROTEIN BOUND WITH GALACTOSE
Descriptor:glucose-binding protein, BETA-D-GALACTOSE
Authors:Cuneo, M.J., Changela, A., Warren, J.J., Beese, L.S., Hellinga, H.W.
Deposit date:2005-09-20
Release date:2006-07-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites.
J.Mol.Biol., 362, 2006
4F3O
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DNA POLYMERASE I LARGE FRAGMENT COMPLEX 5
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(2DT))-3'), DNA (5'-D(*C*AP*TP*GP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-05-09
Release date:2013-07-24
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structures of a High-fidelity DNA Polymerase
to be published
4E0D
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BINARY COMPLEX OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT E658A AND DUPLEX DNA
Descriptor:DNA polymerase, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2012-03-02
Release date:2012-06-06
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
3PX4
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CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I LARGE FRAGMENT BOUND TO DNA AND DDCTP-DA MISMATCH (WOBBLE) IN AJAR CONFORMATION
Descriptor:DNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
Authors:Wang, W., Beese, L.S.
Deposit date:2010-12-09
Release date:2011-10-19
Last modified:2011-11-09
Method:X-RAY DIFFRACTION (1.582 Å)
Cite:Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011