Author results

2O93
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CRYSTAL STRUCTURE OF NFAT BOUND TO THE HIV-1 LTR TANDEM KAPPAB ENHANCER ELEMENT
Descriptor:kappaB enhancer element, DNA 25-mer, actor of activated T-cells, ...
Authors:Bates, D.L., Chen, L.
Deposit date:2006-12-13
Release date:2007-06-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
Structure, 16, 2008
3DFV
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ADJACENT GATA DNA BINDING
Descriptor:DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3'), DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L., Kim, G.K., Guo, L., Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
3DFX
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OPPOSITE GATA DNA BINDING
Descriptor:DNA (5'-D(*DTP*DTP*DGP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DGP*DAP*DGP*DAP*DTP*DAP*DAP*DCP*DC)-3'), DNA (5'-D(*DAP*DAP*DGP*DGP*DTP*DTP*DAP*DTP*DCP*DTP*DCP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L., Kim, G.K., Guo, L., Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
3QB7
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INTERLEUKIN-4 MUTANT RGA BOUND TO CYTOKINE RECEPTOR COMMON GAMMA
Descriptor:Interleukin 4, Cytokine receptor common subunit gamma, SULFATE ION, ...
Authors:Bates, D.L., Junttila, I.S., Creusot, R.J., Moraga, I., Lupardus, P., Fathman, C.G., Paul, W.E., Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.245 Å)
Cite:Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines.
Nat.Chem.Biol., 8, 2012
1P7H
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STRUCTURE OF NFAT1 BOUND AS A DIMER TO THE HIV-1 LTR KB ELEMENT
Descriptor:5'-D(*AP*AP*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*A)-3', 5'-D(*TP*TP*TP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*CP*A)-3', Nuclear factor of activated T-cells, ...
Authors:Giffin, M.J., Stroud, J.C., Bates, D.L., von Koenig, K.D., Hardin, J., Chen, L.
Deposit date:2003-05-01
Release date:2003-09-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element
Nat.Struct.Biol., 10, 2003
2A07
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CRYSTAL STRUCTURE OF FOXP2 BOUND SPECIFICALLY TO DNA.
Descriptor:5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3', 5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3', Forkhead box protein P2, ...
Authors:Stroud, J.C., Wu, Y., Bates, D.L., Han, A., Nowick, K., Paabo, S., Tong, H., Chen, L.
Deposit date:2005-06-16
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Forkhead Domain of FOXP2 Bound to DNA.
Structure, 14, 2006
2AS5
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STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.
Descriptor:5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', Nuclear factor of activated T-cells, ...
Authors:Wu, Y., Stroud, J.C., Borde, M., Bates, D.L., Guo, L., Han, A., Rao, A., Chen, L.
Deposit date:2005-08-22
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126, 2006
2H8N
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STRUCTURE OF A GLUTAMINE-RICH DOMAIN FROM HISTONE DEACETYLASE 4
Descriptor:Histone deacetylase 4
Authors:Guo, L., Han, A., Bates, D.L., Chen, L.
Deposit date:2006-06-07
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2O94
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THE 97H/F MUTANT STRUCTURE OF A GLUTAMINE-RICH DOMAIN FROM HISTONE DEACETYLASE 4
Descriptor:Histone deacetylase 4
Authors:Guo, L., Han, A., Bates, D.L., Chen, L.
Deposit date:2006-12-13
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3GUT
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CRYSTAL STRUCTURE OF A HIGHER-ORDER COMPLEX OF P50:RELA BOUND TO THE HIV-1 LTR
Descriptor:Transcription factor p65, Nuclear factor NF-kappa-B p105 subunit, HIV-LTR Core Forward Strand, ...
Authors:Stroud, J.C., Oltman, A.J., Han, A., Bates, D.L., Chen, L.
Deposit date:2009-03-30
Release date:2009-09-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.
J.Mol.Biol., 393, 2009
3QAZ
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IL-2 MUTANT D10 TERNARY COMPLEX
Descriptor:Interleukin-2, Interleukin-2 receptor subunit beta, Cytokine receptor common subunit gamma, ...
Authors:Levin, A.M., Bates, D.L., Ring, A.M., Lin, J.T., Su, L., Krieg, C., Bowman, G.R., Novick, P., Pande, V.S., Khort, H.E., Boyman, O., Gathman, C.G., Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-11
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (3.802 Å)
Cite:Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
3QB1
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INTERLEUKIN-2 MUTANT D10
Descriptor:Interleukin-2
Authors:Levin, A.M., Bates, D.L., Ring, A.M., Lin, J.T., Su, L., Krieg, C., Bowman, G.R., Novick, P., Pande, V.S., Khort, H.E., Boyman, O., Fathman, C.G., Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
4HC7
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CRYSTAL STRUCTURE OF THE FULL DNA BINDING DOMAIN OF GATA3-COMPLEX 2
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HC9
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 3
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HCA
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 1
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
3FYL
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GR DNA BINDING DOMAIN:CGT COMPLEX
Descriptor:Glucocorticoid receptor, DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*TP*TP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*AP*AP*AP*AP*TP*GP*TP*TP*CP*T)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-01-22
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6P
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GR DNA BINDING DOMAIN:FKBP5 COMPLEX, 18BP
Descriptor:DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*TP*G)-3'), Glucocorticoid receptor, ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-07
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.985 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6Q
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GR DNA BINDING DOMAIN:FKBP5 BINDING SITE COMPLEX-9
Descriptor:Glucocorticoid receptor, DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*T)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-08
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6R
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GR DNA BINDING DOMAIN:FKBP5 COMPLEX-52, 18BP
Descriptor:DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*TP*G)-3'), Glucocorticoid receptor, ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-08
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6T
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GR GAMMA DNA-BINDING DOMAIN:FKBP5 16BP COMPLEX-34
Descriptor:Glucocorticoid receptor, DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*T)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-08
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6U
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GR DNA-BINDING DOMAIN:FKBP5 16BP COMPLEX-49
Descriptor:Glucocorticoid receptor, DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*T)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-08
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G8U
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DNA BINDING DOMAIN:GILZ 16BP COMPLEX-5
Descriptor:Glucocorticoid receptor, DNA (5'-D(*TP*GP*GP*AP*AP*CP*CP*CP*AP*AP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*GP*GP*GP*TP*TP*CP*C)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-12
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G8X
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GR DNA BINDING DOMAIN:GILZ 16BP COMPLEX-65
Descriptor:Glucocorticoid receptor, DNA (5'-D(*TP*GP*GP*AP*AP*CP*CP*CP*AP*AP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*GP*GP*GP*TP*TP*CP*C)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-12
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G97
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GR DNA-BINDING DOMAIN:GILZ 16BP COMPLEX-9
Descriptor:Glucocorticoid receptor, DNA (5'-D(*TP*GP*GP*AP*AP*CP*CP*CP*AP*AP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*GP*GP*GP*TP*TP*CP*C)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-13
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G99
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GR DNA BINDING DOMAIN:PAL COMPLEX-9
Descriptor:Glucocorticoid receptor, DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*AP*AP*AP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*TP*TP*GP*TP*TP*CP*T)-3'), ...
Authors:Pufall, M.A., Yamamoto, K.R., Meijsing, S.H.
Deposit date:2009-02-13
Release date:2009-04-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
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