3QAZ

IL-2 mutant D10 ternary complex

Summary for 3QAZ

Entry DOI	10.2210/pdb3qaz/pdb
Related	1Z92 2B5I
Descriptor	Interleukin-2, Interleukin-2 receptor subunit beta, Cytokine receptor common subunit gamma, ... (4 entities in total)
Functional Keywords	cytokine receptor signaling complex, signaling protein-cytokine complex, signaling protein/cytokine
Biological source	Homo sapiens (human) More
Total number of polymer chains	36
Total formula weight	791555.45
Authors	Levin, A.M.,Bates, D.L.,Ring, A.M.,Lin, J.T.,Su, L.,Krieg, C.,Bowman, G.R.,Novick, P.,Pande, V.S.,Khort, H.E.,Boyman, O.,Gathman, C.G.,Garcia, K.C. (deposition date: 2011-01-12, release date: 2012-04-11, Last modification date: 2020-07-29)
Primary citation	Levin, A.M.,Bates, D.L.,Ring, A.M.,Krieg, C.,Lin, J.T.,Su, L.,Moraga, I.,Raeber, M.E.,Bowman, G.R.,Novick, P.,Pande, V.S.,Fathman, C.G.,Boyman, O.,Garcia, K.C. Exploiting a natural conformational switch to engineer an interleukin-2 'superkine' Nature, 484:529-533, 2012 Cited by PubMed: 22446627 DOI: 10.1038/nature10975 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.802 Å)

Structure validation