2A07

Crystal Structure of Foxp2 bound Specifically to DNA.

Summary for 2A07

Descriptor5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3', 5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3', Forkhead box protein P2, ... (5 entities in total)
Functional Keywordsforkhead, double-helix, swapping, homodimer, monomer, winged-helix, magnesium, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
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Cellular locationNucleus  O15409
Total number of polymer chains10
Total molecular weight92060.44
Authors
Stroud, J.C.,Wu, Y.,Bates, D.L.,Han, A.,Nowick, K.,Paabo, S.,Tong, H.,Chen, L. (deposition date: 2005-06-16, release date: 2006-01-31, Last modification date: 2011-07-13)
Primary citation
Stroud, J.C.,Wu, Y.,Bates, D.L.,Han, A.,Nowick, K.,Paabo, S.,Tong, H.,Chen, L.
Structure of the Forkhead Domain of FOXP2 Bound to DNA.
Structure, 14:159-166, 2006
PubMed: 16407075 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2005.10.005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.250160.8%1.8%10.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2a07
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Molmil generated image of 2a07
rotated about x axis by 90°
Molmil generated image of 2a07
rotated about y axis by 90°